godfather of surgery

Chapter 286 Genetic Testing

The next day, Wei Danian was completely out of danger.

The blood pH value returned to the normal range, 7.40; blood lactic acid also dropped to the normal range, 1.0mmol/l, and other electrolytes potassium, sodium, chloride and calcium all returned to the normal range.

As long as the acid-base imbalance and electrolyte imbalance are corrected and the patient returns to a stable internal environment, life will be out of danger.

The internal environment of human cells, like the human living environment, must be maintained within certain parameters, otherwise survival will be threatened.

Wei Danian's tracheal intubation was successfully removed, but just to be on the safe side, he still needs to be monitored in the ICU for a day before being transferred to the general ward.

In the ICU ward, there are all patients who are seriously ill, and patients who cannot be rescued will die at any time. Wei Danian can only lie on the bed, with various tubes and lines connected to his body. He is naturally terrified. Shout out.

Doctors and nurses kept persuading him. The 25-year-old man was as stubborn as a child. There was nothing he could do. Dr. An contacted Dr. Jin and planned to transfer to the trauma orthopedics department.

But before the phone was hung up, Wei Danian fell asleep again, snoring like thunder, and there was a burst of snoring. Suddenly, there was no movement again, and the ECG monitor actually showed that he had stopped breathing. Dr. An hurriedly approached his nose to listen to his breathing, and it was really breathing. Stop, for a moment, Wei Danian opened his eyes, looked around in a daze, then snored like thunder again, and his breathing resumed.

Obstructive Sleep Apnea Hypopnea Syndrome is a near-miss. This disease is common in obese men. Often at night, the upper airway collapses and obstructs, leading to apnea. Then the patient wakes up and resumes breathing.

"Let's record the course of the disease. After being transferred to the orthopedics department, it is recommended to consult the respiratory department and do sleep apnea monitoring." Dr. An instructed Gui Peisheng who was beside him.

Dr. Jin asked Wei Danian's parents about the number of attacks each year and the specific month in detail, and drew a statistical chart. According to the statistical law shown in the statistical chart, the attack will not occur within three months.

Before the internal law is found, this superficial law can also play a predictive role, at least it can guide the patient which season and which month are the most dangerous in each year.

Dr. Jin will report the results of Wei Danian's inspection in the group once a day for everyone to analyze and discuss how to check next.

The blood sugar is controlled very well, and the increase of blood lactic acid caused by diabetes can be ruled out. According to the test results, acquired diseases have also been ruled out one by one. Everyone focuses on genetic diseases. Although they have been checked in other hospitals, it is very helpful to check again necessary.

Wei Danian's parents agreed to investigate the cause of the disease, and the dead horse is a living horse doctor. The doctor is so enthusiastic, of course they are willing to cooperate. With such an only child, he is worried every day. This curse.

"Can you contact the genetic laboratory of Southern Metropolis Medical University for gene sequencing?" Yang Ping suggested to Dr. Jin.

Considering genetic diseases, it is necessary to conduct gene sequencing to find the cause at the genetic level, investigate family medical history, and draw family genetic pedigree.

"Contacting the genetic laboratory of Nandu Medical University? It's a bit difficult!" Dr. Jin responded.

"I'll get in touch!" Yang Ping responded.

"There is a problem with the conversion of pyruvate, an enzyme defect, or abnormal function of the mitochondria that process lactic acid, which can only be understood by gene sequencing." Yang Ping analyzed.

"Congenital lactic acidosis is the deficiency of the enzyme structure or activity of pyruvate conversion. It was first reported by Hartmann et al. in 1962. It is transmitted by X-linked inheritance. The mutant gene is on Xpz. Patients generally have mental and motor function development retardation. He also has hepatomegaly, heart enlargement, cataract, etc. It is recommended to use the intelligence test scale to test intelligence and evaluate motor function. It is strange that this patient does not have hepatomegaly, no cataract, and the heart size and body shape also match." A doctor of endocrinology Views.

Contacting Nandu Medical University, looking for Su Nanchen is the best way. Yang Ping contacted Su Nanchen on WeChat, explained his thoughts, and sent him the medical records. Su Nanchen was very interested and immediately recommended a young female doctor in the genetic laboratory of Nandu Medical University- ——Wen Yulin.

Efficiency is high in the Internet era. Soon, Su Nanchen and Dr. Wen were pulled into the group. Dr. Jin reposted Wei Danian's information so that they could see it. He also sent the screenshot of the discussion just now to the group. Keep them updated on how the discussion is going.

Dr. Wen was very interested in the case and quickly responded: "Our laboratory can detect gene fragments and detect whether there is a mutation in Xpz."

"How to collect and store specimens, do they need ethical approval? Also, the cost?"

The discussion speeches in the group began to flood the screen like snowflakes. The discussion has been upgraded from clinical to genetic testing level, and everyone is extremely excited.

This is a challenging cooperation. Clinicians and basic medical researchers rarely meet each other. When doctors are studying for postgraduate research, they may also deal with basic medical researchers. Once they enter the clinic, they will never communicate with each other.

"I'll send you the detailed specimen collection and ethical procedures later—" Dr. Wen was very active.

From a patient's clinical symptoms, follow the clues, gradually deepen, and enter the level of genetic testing, all kinds of knowledge that are usually isolated are connected in series.

This is destined not to be an ordinary case. Yang Ping faintly felt that this case would create a new diagnostic model, and it was very possible to find an unknown disease.

Because none of the existing known diseases can match Wei Danian's condition.

Medicine needs this group of passionate and courageous people to challenge the unknown, without paranoia, without madness, and it is difficult to move forward on the road of overcoming obstacles.

As the Spring Festival approached, the festive atmosphere became more and more intense. The hospital also began to hang red lanterns in advance. The leaders of the hospital inspected various departments and departments, issued three orders and five orders, and arranged holiday schedules to ensure medical safety during holidays.

Usually at this time, everyone is discussing the Spring Festival holiday or grabbing tickets, but the doctors and nurses are very calm, because no one is on vacation, so there is no such thing.

Zhang Lin made out the duty schedule for everyone to look at. If there is no special event, this schedule will be implemented during the Spring Festival.
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Luo Jin participated in the recording of the hospital's promotional video, and also participated in the recording of a comprehensive orthopedic documentary. The TV station specially added an episode for him to record his injury, surgery and recovery process.

Hermes was discharged from the hospital, and he went to the outpatient clinic to continue treatment. The emaciated camel was bigger than a horse. He sold a house near the hospital, a duplex house of more than 200 square meters, and received more than 1000 million in cash after the sale.

This guy is very economical. He used cash to buy another 140-square-meter house near the hospital for himself to live in. With the remaining 400 million cash, he bought a small investment house near the Nandu high-speed rail station. I still hold 100 million in cash in my hand, and use it to treat illnesses, looking for opportunities to make a comeback.

With such an operation, although the house has become smaller, there are still houses, cash, and a small house that can appreciate in value.

When Hermès was hospitalized, it was at the peak of the price increase in the community next to the hospital. Unexpectedly, now that he made a move, he not only earned back the medical expenses, but also made a lot of money.

Fortunately, Hermès just went bankrupt, and other worries, such as going to jail, did not happen for the time being.

I just heard that he went bankrupt and was at risk of being imprisoned. Those relatives and friends lost contact with Hermes, including relatives who were often helped by Hermes.

The rich live in the mountains and have distant relatives, but the poor live in the busy city and no one cares about them.

In the past, although he traveled far away to G City to seek medical treatment, relatives and friends kept sending condolence calls, there were messages of concern on WeChat from time to time, and people often sent various precious medicinal materials to the hospital.

Now, overnight, it seems that the mobile phone has been disconnected from the Internet, and there are no calls. It is surprisingly quiet. Occasionally, Hermès wants to inquire about news, calls relatives and friends, and sends WeChat, but there is no response, and some simply block.

After this accident, my eldest brother went to the oncology department again, and he has a deeper understanding of life. He no longer struggles with the huge gap and faces life calmly.

As Yang Ping told him: "If there is no obvious abnormality on these checklists, it is your greatest happiness."

Hermès bought a good set of stereos, and every day when he had nothing to do, he asked his wife to push him on the flyover next to the hospital, and sang an old song "Broad Sea and Sky" at the top of his voice. The eldest brother may have experienced ups and downs by himself, and he sang this song with sincerity and heart. .

The passers-by burst into tears, and although there was no bowl in front of them to beg for money, the kind passers-by generously donated money, throwing one yuan and ten yuan in change in front of him.

But they were all picked up by Hermès and returned to passers-by. The eldest brother sang, just looking for freedom. Although he was down and out, he was not short of this money.

With the cash from selling the house in hand, you can go in and out of the stock market on your mobile phone every day, and you can also earn money to support your family. The investment mind is also a survival skill at this time.

Sisi's surgery is in the third phase, dealing with lung tumors. Because of the obstruction of the ribs, it is very difficult to focus high-frequency ultrasound on the lungs. Ultrasound can only pass through the narrow rib gap.

However, Yang Ping has repeatedly simulated in the system space and obtained accurate data, which can be used to complete the operation.

Medicine, iron and fire!The energy represented by fire will definitely shine in the future.

Perhaps one day, many surgical operations do not even need minimally invasive small incisions, and the use of these energies can be used to remove the lesion.

That will be a brand new era.

(End of this chapter)