I can see health
Chapter 579
Chapter 579 Dilemma
After dealing with Li Wenqian's "heart discomfort" patient, Lu Chen continued to look for clues to his other patients' diagnosis.
He also gradually liked this process.
Just like a detective solving a case, gather all the details together, and finally pull out the cocoons to make a reasonable reasoning diagnosis.
In addition to clinical training, another main purpose of Lu Chen's trip to Kyoto this time is to cooperate with the third heart area of the First Affiliated Hospital of Kyoto University to conduct clinical research experiments.
"Lu Chen, Director Wan asked you to come to the third area of your heart tomorrow to discuss the experiment."
When getting off work, Ke Yue suddenly sent Lu Chen a WeChat message.
"Okay, received." Lu Chen replied immediately.
As the sub-center of scientific research in Kyoto, the third heart area also undertakes many tasks.
Tomorrow happens to be the weekend, this time it should be to discuss specific matters with Director Wan.
……
The next day.
Lu Chen got up early, and several roommates in the dormitory went to the library to study, while he went to the third area of the heart.
The third heart area is two floors above the first heart area.
There were also many people waiting for the elevator on weekends, so Lu Chen climbed the stairs.
As soon as he entered the third area of his heart, he saw Ke Yue and Gu Xinyue chatting in front of the nurse's station.
"Lao Gu is usually so cold, today is a bit unusual!" Lu Chen smiled secretly, and then walked forward.
Because the two were facing Lu Chen with their backs, even if Lu Chen approached, the two hadn't noticed Lu Chen's arrival.
Lu Chen got closer and heard Gu Xinyue say.
"Ke Yue, what are the statistical methods involved in your overall experimental procedures? I've been looking at it for a long time, but I don't really understand it."
Ke Yue paused, and said: "The main thing is survival curve analysis, COX regression analysis, more specific needs to ask Lu Chen, other I am also learning statistics now, this is too difficult."
"Oh, okay." Gu Xinyue nodded.
At this moment, Ke Yue glimpsed Lu Chen from the corner of his eye.
"Hey, Lu Chen, you're here."
Lu Chen stopped hiding, stood up and said with a smile, "What are you two doing sneaking around?"
When Gu Xinyue heard Lu Chen's voice, she immediately stood up straight.
"Lao Gu said that he would come to study with us, so I brought him here." Ke Yue blushed, she was already thin-skinned and couldn't stand being teased by others.
"Oh... really?" Lu Chen glanced at Gu Xinyue.
"Well, don't get me wrong." Gu Xinyue cleared her throat, "We are discussing the experiment."
Lu Chen looked at the embarrassment of the two, and stopped teasing them, "Is Director Wan here?"
"Here." Ke Yue nodded, "He comes to the department at seven every day."
"It's so early, Director Wan!" Lu Chen sighed.
None of these director-level figures sleep late.
"Let's go to the office."
Led by Lu Chen, the three came to the director's office.
bang bang...
Lu Chen gently knocked on the door.
"go ahead!"
There was a deep voice in the room, and Lu Chen pushed the door open and entered.
In the director's office, Director Wan Jingshui was discussing something with Fang Ruzhang.
Seeing Lu Chen walk in, Wan Jingshui quickly stood up with a smile on his face.
"Classmate Lu Chen is here!"
Fang Ruzhang also stood up immediately, "Lu Chen, you are here!"
Lu Chen walked into the office with a smile, "Director Wan, Teacher Fang, long time no see!"
"Come on, there's no need to greet, Fang Ruzhang and I are discussing some experimental issues, and you came just in time." Wan Jingshui didn't even smudge, and directly pulled Lu Chen to sit on the sofa, with Ke Yue and Fang Ruzhang also sitting beside him.
"You should know about the recent AstraZeneca incident, right?" Wan Jingshui looked serious.
Lu Chen nodded slightly, "AstraZeneca announced an experimental protocol similar to ours."
"Hey, after all, they are the original research company of Dapagliflozin." Wan Jingshui sighed, "Although we started the experiment early and have certain advantages, but facing a giant multinational company like AstraZeneca, I don't know. I still feel stuck!"
When Wan Jingshui first heard about Lu Chen's clinical research project, he had particularly high expectations for it.
Once the research results are finally removed, it may change the clinical guidelines!
Hearing this, Lu Chen fell silent.
Wan Jingshui's words are very reasonable. In a scientific research competition with AstraZeneca, the winning rate will not be too high!
"Director Wan, do you think there is any way to break the situation now?" Lu Chen paused, then looked up at Wan Jingshui and Fang Ruzhang.
In terms of clinical scientific research, his experience is still inexperienced, far inferior to those at the director level.
Wan Jingshui glanced at Fang Ruzhang who was at the side.
Fang Ruzhang understood, and said slowly: "There are two options, first, that is to withdraw from the competition, we can only publish the experimental results in China, just ensure that your national nature project is completed, as for how much influence it will have in the world , then resign to fate.”
To put it bluntly, the first option is to lie flat!
As long as you can publish a few SCI papers, you don't need to be too high-quality, and you don't need to publish papers faster than Oscars, as long as you can pass the National Natural Science Papers.
This is not the same as Lu Chen's original idea.
"Teacher Fang, what about the second type?" Lu Chen stared at Fang Ruzhang closely.
"As for the second one..." Fang Ruzhang paused, and a gleam flashed in his eyes, "That is to expand the scale of the experiment and compete with AstraZeneca!"
Clinical scientific research experiments are different from basic scientific research experiments, the most needed is the experimental scale!
The larger the experimental sample size, the more convincing the experimental results will be!
With a sample of 100 people and a sample of 1 people, it is obvious which paper is of high quality.
"As far as I know, the number of people in AstraZeneca's first batch of experiments is around 1000." Lu Chen said.
With a sample size of 1000 people, it is not a small sum to bear the inspection costs of the experimenters, drug usage fees, etc.
For Lu Chen's current clinical trials, the total number of people in Jinghua and other places has never been more than 400!
Four hundred and one thousand, the difference is not small!
What's more, this is still the first round of competition.
This competition is manpower, material and financial resources!
It is far from enough to rely solely on the scientific research funds of the National Natural Science Foundation of China!
"Hey, that's why it's difficult!" Wan Jingshui shook his head slightly, "Your supervisor, Professor Li Yao, has also contacted me, and she can't make a decision yet, so let me discuss it with you."
Wan Jingshui values Lu Chen's scientific research project very much, and believes that some achievements will be made, so he is willing to run around.
Lu Chen thought for a while, and now he was in a dilemma.
If you give up, you will lose such a good opportunity.
Persistence, the price paid is several times higher than it is now.
The most important thing is that he is only a student now, what method can he continue to expand the scale of the experiment?
(End of this chapter)
After dealing with Li Wenqian's "heart discomfort" patient, Lu Chen continued to look for clues to his other patients' diagnosis.
He also gradually liked this process.
Just like a detective solving a case, gather all the details together, and finally pull out the cocoons to make a reasonable reasoning diagnosis.
In addition to clinical training, another main purpose of Lu Chen's trip to Kyoto this time is to cooperate with the third heart area of the First Affiliated Hospital of Kyoto University to conduct clinical research experiments.
"Lu Chen, Director Wan asked you to come to the third area of your heart tomorrow to discuss the experiment."
When getting off work, Ke Yue suddenly sent Lu Chen a WeChat message.
"Okay, received." Lu Chen replied immediately.
As the sub-center of scientific research in Kyoto, the third heart area also undertakes many tasks.
Tomorrow happens to be the weekend, this time it should be to discuss specific matters with Director Wan.
……
The next day.
Lu Chen got up early, and several roommates in the dormitory went to the library to study, while he went to the third area of the heart.
The third heart area is two floors above the first heart area.
There were also many people waiting for the elevator on weekends, so Lu Chen climbed the stairs.
As soon as he entered the third area of his heart, he saw Ke Yue and Gu Xinyue chatting in front of the nurse's station.
"Lao Gu is usually so cold, today is a bit unusual!" Lu Chen smiled secretly, and then walked forward.
Because the two were facing Lu Chen with their backs, even if Lu Chen approached, the two hadn't noticed Lu Chen's arrival.
Lu Chen got closer and heard Gu Xinyue say.
"Ke Yue, what are the statistical methods involved in your overall experimental procedures? I've been looking at it for a long time, but I don't really understand it."
Ke Yue paused, and said: "The main thing is survival curve analysis, COX regression analysis, more specific needs to ask Lu Chen, other I am also learning statistics now, this is too difficult."
"Oh, okay." Gu Xinyue nodded.
At this moment, Ke Yue glimpsed Lu Chen from the corner of his eye.
"Hey, Lu Chen, you're here."
Lu Chen stopped hiding, stood up and said with a smile, "What are you two doing sneaking around?"
When Gu Xinyue heard Lu Chen's voice, she immediately stood up straight.
"Lao Gu said that he would come to study with us, so I brought him here." Ke Yue blushed, she was already thin-skinned and couldn't stand being teased by others.
"Oh... really?" Lu Chen glanced at Gu Xinyue.
"Well, don't get me wrong." Gu Xinyue cleared her throat, "We are discussing the experiment."
Lu Chen looked at the embarrassment of the two, and stopped teasing them, "Is Director Wan here?"
"Here." Ke Yue nodded, "He comes to the department at seven every day."
"It's so early, Director Wan!" Lu Chen sighed.
None of these director-level figures sleep late.
"Let's go to the office."
Led by Lu Chen, the three came to the director's office.
bang bang...
Lu Chen gently knocked on the door.
"go ahead!"
There was a deep voice in the room, and Lu Chen pushed the door open and entered.
In the director's office, Director Wan Jingshui was discussing something with Fang Ruzhang.
Seeing Lu Chen walk in, Wan Jingshui quickly stood up with a smile on his face.
"Classmate Lu Chen is here!"
Fang Ruzhang also stood up immediately, "Lu Chen, you are here!"
Lu Chen walked into the office with a smile, "Director Wan, Teacher Fang, long time no see!"
"Come on, there's no need to greet, Fang Ruzhang and I are discussing some experimental issues, and you came just in time." Wan Jingshui didn't even smudge, and directly pulled Lu Chen to sit on the sofa, with Ke Yue and Fang Ruzhang also sitting beside him.
"You should know about the recent AstraZeneca incident, right?" Wan Jingshui looked serious.
Lu Chen nodded slightly, "AstraZeneca announced an experimental protocol similar to ours."
"Hey, after all, they are the original research company of Dapagliflozin." Wan Jingshui sighed, "Although we started the experiment early and have certain advantages, but facing a giant multinational company like AstraZeneca, I don't know. I still feel stuck!"
When Wan Jingshui first heard about Lu Chen's clinical research project, he had particularly high expectations for it.
Once the research results are finally removed, it may change the clinical guidelines!
Hearing this, Lu Chen fell silent.
Wan Jingshui's words are very reasonable. In a scientific research competition with AstraZeneca, the winning rate will not be too high!
"Director Wan, do you think there is any way to break the situation now?" Lu Chen paused, then looked up at Wan Jingshui and Fang Ruzhang.
In terms of clinical scientific research, his experience is still inexperienced, far inferior to those at the director level.
Wan Jingshui glanced at Fang Ruzhang who was at the side.
Fang Ruzhang understood, and said slowly: "There are two options, first, that is to withdraw from the competition, we can only publish the experimental results in China, just ensure that your national nature project is completed, as for how much influence it will have in the world , then resign to fate.”
To put it bluntly, the first option is to lie flat!
As long as you can publish a few SCI papers, you don't need to be too high-quality, and you don't need to publish papers faster than Oscars, as long as you can pass the National Natural Science Papers.
This is not the same as Lu Chen's original idea.
"Teacher Fang, what about the second type?" Lu Chen stared at Fang Ruzhang closely.
"As for the second one..." Fang Ruzhang paused, and a gleam flashed in his eyes, "That is to expand the scale of the experiment and compete with AstraZeneca!"
Clinical scientific research experiments are different from basic scientific research experiments, the most needed is the experimental scale!
The larger the experimental sample size, the more convincing the experimental results will be!
With a sample of 100 people and a sample of 1 people, it is obvious which paper is of high quality.
"As far as I know, the number of people in AstraZeneca's first batch of experiments is around 1000." Lu Chen said.
With a sample size of 1000 people, it is not a small sum to bear the inspection costs of the experimenters, drug usage fees, etc.
For Lu Chen's current clinical trials, the total number of people in Jinghua and other places has never been more than 400!
Four hundred and one thousand, the difference is not small!
What's more, this is still the first round of competition.
This competition is manpower, material and financial resources!
It is far from enough to rely solely on the scientific research funds of the National Natural Science Foundation of China!
"Hey, that's why it's difficult!" Wan Jingshui shook his head slightly, "Your supervisor, Professor Li Yao, has also contacted me, and she can't make a decision yet, so let me discuss it with you."
Wan Jingshui values Lu Chen's scientific research project very much, and believes that some achievements will be made, so he is willing to run around.
Lu Chen thought for a while, and now he was in a dilemma.
If you give up, you will lose such a good opportunity.
Persistence, the price paid is several times higher than it is now.
The most important thing is that he is only a student now, what method can he continue to expand the scale of the experiment?
(End of this chapter)
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