Big Doctor Live Room
Chapter 1261 Reverse Gene Therapy
Chapter 1261 Reverse Gene Therapy
Chen Qun nodded, directly acknowledging Dean Schneider's opinion.
"Yes, the danger of polio virus is that it can easily infiltrate nerve tissue, so this is the best vector!"
"Then how do you do it? Put the genetic code on the virus!"
Dean Schneider pointed straight to the core. Many things are very easy to say, but it is extremely difficult to realize them.Since Chen Qun came up with a plan, there must be a perfect plan.The last time he performed remote heart surgery on Thomas, he only had half an hour to think about it before he came up with a perfect solution.
Now they have been discussing for several days, and there will definitely be a big surprise.
"It seems that five or six years ago, a doctor tried to use gene editing technology to treat Parkinson's disease, but the result was a failure. This experiment was also conducted by a research institute under the name of Neo, although A few years have passed, and it is considered outdated for the ever-growing medical technology, but this experiment has inadvertently provided us with an idea, so we have improved it on the basis of this technology, and perhaps we can do it this time. There is a certain effect in the reversal therapy of
Dean Schneider looked at Chen Qun in surprise, not knowing what he meant by saying this.However, he was very clear in his heart that the surgeon Chen was talking about was himself. He joined the experiment anonymously, hoping to achieve some results, but it failed.
He also wrote a stinky and long paper on this at the time, explaining the entire failure process, hoping that other latecomers will not make the same mistakes as their experimental group.Chen can openly find this paper from some old journals and websites, but it is almost impossible to know that he was also a participant back then.
After all, he participated under a pseudonym at that time. He was mostly responsible for the theoretical part, so he did not go to the institute for field operations. In fact, there was no need for him to go there.At that time, he was busy competing for the position of director of Charlotte Hospital and was extremely busy, so he adopted this last resort method to participate in normal academic research.
Seeing that Chen Qun had found out his failed plan, Schneider became more curious, and after careful consideration, it is impossible for the Chinese to know about this very low-key and secretive affair, even his own daughter, who just went to college. Naturally, Chen Qun couldn't hear it from his daughter.
As for Neo Company, except for the leader of the project team who was in charge of this research, no one else knew his true identity.Now that old friend has passed away due to an accident, it is even less likely that there will be any information left, and it is naturally impossible for Chen Qun to know who he is.
Besides, the young man Chen didn't show any strange expression to himself when he narrated just now, which shows that he was just explaining an academic paper.
Dean Schneider stared at Chen Qun, and continued to question Chen Qun pretending not to understand.
"What exactly do you mean by improvement, can you be more specific?"
Chen Qun has mastered the "black material" of this old man from the system space, and seeing his indifferent appearance, he also admires that these old guys are indeed the elite among the elites, and they are indeed the heads of the top ten hospitals in the world , his little trick is naturally ineffective for him.Even if he exposes his background, it will have no effect on him, and he will even win praise.
Since everyone is pretending to be confused, then being confused together is really stupid.
"The delivery mechanism in that experiment was varicella zoster virus. The reason why it failed was because the first choice was herpes simplex virus. The technology at that time could not deliver DNA to herpes simplex virus, but now the technology has improved. , can do this.”
"You mean the new application of mRNA technology?"
"Yes, although the technical details are a little different, it is not wrong to think that it is similar to the messenger RNA technology. This time we encoded the messenger RNA on the poliovirus. reversing gene editing in patients."
"How can you be sure that this virus will not cause other harm to the patient?"
"Of course, we first culture human cells in vitro, and then infect the virus to determine whether it is effective. We only need to achieve effective target positioning, the more we can ensure that the virus cells will not damage other human cells, and finally achieve the effect. If If conditions permit, we can even allow large animals to repeat the patient's gene editing first, and then give drug treatment. Although it will take more than half a year, it is better than letting the patient die."
Dean Schneider tapped the table twice with his finger, and asked the last question again.
"If such a rigorous medical experiment is to be carried out, it will cost hundreds of thousands or even millions of euros. Is it too expensive?"
Chen Qun looked at Dean Schneider, and suddenly understood that the old gentleman had already agreed to his idea, and now he was just helping himself to convince others, and gave the answer directly.
"On the contrary, Mr. Dean, I think this kind of investment is a once-in-a-lifetime opportunity. It allows us to move from theory to practical application in the field of genetics in modern medicine. If we only treat one person, it does cost too much." It’s big, but the results of this experiment should benefit more people, and the investment of several million euros is really worth it!”
"Aren't you afraid to open Pandora's Box?"
"In fact, this is not a Pandora's box at all. This box has long been opened. Transcription gene technology has been used on a large scale in many fields. Now it is used for the first time in reverse transgene technology. This is very groundbreaking. .If the patient gives up treatment because the cost is too high, then our Meiling Medical Research Center is willing to continue to provide all treatment and development. We will bring the patient back to China, and perhaps we can also cooperate with Charlotte Hospital. We provide drugs. You conduct tests and monitor each other to ensure patients receive the best care."
Dean Schneider's eyes immediately lit up. As a doctor, he certainly supports the treatment of patients, but as the president of Europe's leading famous hospital, he needs to consider the interests of the hospital.If Chen Qun is willing to be taken advantage of and pay for treatment, as long as the patient stays in Charlotte Hospital, then the success will be half as good as Charlotte's.
Of course, the form of cooperation is not important, what is important is that Chen Qun is more likely to cure the patient, which is also a very important support for him, after all, this is also the field he is involved in.If he had a more vigorous partner, then he, the dean, would have more confidence in the face of a cross-border medical group like Neo Company.
Chen Qun's surgical technique alone can be said to be No. 1 in the field of surgery in the world, including the field of minimally invasive surgery. Charlotte Hospital must cooperate with Chen Qun to treat those top figures. This is the relationship between him and Chen Qunguang. Already share a common interest base.Now coupled with Chen Qun's scientific research ability, even if he is not the world's best, his luck is also the world's number one, which is enough to use this cover to bargain from other multinational medical groups and get more benefits.
The reason why Chen Qun did this was to lead the Xiangyun Hospital he worked for to become a world-class hospital. Even with a genius like Chen Qun and a talented team, with the medical level of the Far East, if he wanted to catch up with and surpass Xia Lute, at least needs Chen to fight for a lifetime, and there is no threat to him now and in the future, so he naturally raised his hand in favor.
(End of this chapter)
Chen Qun nodded, directly acknowledging Dean Schneider's opinion.
"Yes, the danger of polio virus is that it can easily infiltrate nerve tissue, so this is the best vector!"
"Then how do you do it? Put the genetic code on the virus!"
Dean Schneider pointed straight to the core. Many things are very easy to say, but it is extremely difficult to realize them.Since Chen Qun came up with a plan, there must be a perfect plan.The last time he performed remote heart surgery on Thomas, he only had half an hour to think about it before he came up with a perfect solution.
Now they have been discussing for several days, and there will definitely be a big surprise.
"It seems that five or six years ago, a doctor tried to use gene editing technology to treat Parkinson's disease, but the result was a failure. This experiment was also conducted by a research institute under the name of Neo, although A few years have passed, and it is considered outdated for the ever-growing medical technology, but this experiment has inadvertently provided us with an idea, so we have improved it on the basis of this technology, and perhaps we can do it this time. There is a certain effect in the reversal therapy of
Dean Schneider looked at Chen Qun in surprise, not knowing what he meant by saying this.However, he was very clear in his heart that the surgeon Chen was talking about was himself. He joined the experiment anonymously, hoping to achieve some results, but it failed.
He also wrote a stinky and long paper on this at the time, explaining the entire failure process, hoping that other latecomers will not make the same mistakes as their experimental group.Chen can openly find this paper from some old journals and websites, but it is almost impossible to know that he was also a participant back then.
After all, he participated under a pseudonym at that time. He was mostly responsible for the theoretical part, so he did not go to the institute for field operations. In fact, there was no need for him to go there.At that time, he was busy competing for the position of director of Charlotte Hospital and was extremely busy, so he adopted this last resort method to participate in normal academic research.
Seeing that Chen Qun had found out his failed plan, Schneider became more curious, and after careful consideration, it is impossible for the Chinese to know about this very low-key and secretive affair, even his own daughter, who just went to college. Naturally, Chen Qun couldn't hear it from his daughter.
As for Neo Company, except for the leader of the project team who was in charge of this research, no one else knew his true identity.Now that old friend has passed away due to an accident, it is even less likely that there will be any information left, and it is naturally impossible for Chen Qun to know who he is.
Besides, the young man Chen didn't show any strange expression to himself when he narrated just now, which shows that he was just explaining an academic paper.
Dean Schneider stared at Chen Qun, and continued to question Chen Qun pretending not to understand.
"What exactly do you mean by improvement, can you be more specific?"
Chen Qun has mastered the "black material" of this old man from the system space, and seeing his indifferent appearance, he also admires that these old guys are indeed the elite among the elites, and they are indeed the heads of the top ten hospitals in the world , his little trick is naturally ineffective for him.Even if he exposes his background, it will have no effect on him, and he will even win praise.
Since everyone is pretending to be confused, then being confused together is really stupid.
"The delivery mechanism in that experiment was varicella zoster virus. The reason why it failed was because the first choice was herpes simplex virus. The technology at that time could not deliver DNA to herpes simplex virus, but now the technology has improved. , can do this.”
"You mean the new application of mRNA technology?"
"Yes, although the technical details are a little different, it is not wrong to think that it is similar to the messenger RNA technology. This time we encoded the messenger RNA on the poliovirus. reversing gene editing in patients."
"How can you be sure that this virus will not cause other harm to the patient?"
"Of course, we first culture human cells in vitro, and then infect the virus to determine whether it is effective. We only need to achieve effective target positioning, the more we can ensure that the virus cells will not damage other human cells, and finally achieve the effect. If If conditions permit, we can even allow large animals to repeat the patient's gene editing first, and then give drug treatment. Although it will take more than half a year, it is better than letting the patient die."
Dean Schneider tapped the table twice with his finger, and asked the last question again.
"If such a rigorous medical experiment is to be carried out, it will cost hundreds of thousands or even millions of euros. Is it too expensive?"
Chen Qun looked at Dean Schneider, and suddenly understood that the old gentleman had already agreed to his idea, and now he was just helping himself to convince others, and gave the answer directly.
"On the contrary, Mr. Dean, I think this kind of investment is a once-in-a-lifetime opportunity. It allows us to move from theory to practical application in the field of genetics in modern medicine. If we only treat one person, it does cost too much." It’s big, but the results of this experiment should benefit more people, and the investment of several million euros is really worth it!”
"Aren't you afraid to open Pandora's Box?"
"In fact, this is not a Pandora's box at all. This box has long been opened. Transcription gene technology has been used on a large scale in many fields. Now it is used for the first time in reverse transgene technology. This is very groundbreaking. .If the patient gives up treatment because the cost is too high, then our Meiling Medical Research Center is willing to continue to provide all treatment and development. We will bring the patient back to China, and perhaps we can also cooperate with Charlotte Hospital. We provide drugs. You conduct tests and monitor each other to ensure patients receive the best care."
Dean Schneider's eyes immediately lit up. As a doctor, he certainly supports the treatment of patients, but as the president of Europe's leading famous hospital, he needs to consider the interests of the hospital.If Chen Qun is willing to be taken advantage of and pay for treatment, as long as the patient stays in Charlotte Hospital, then the success will be half as good as Charlotte's.
Of course, the form of cooperation is not important, what is important is that Chen Qun is more likely to cure the patient, which is also a very important support for him, after all, this is also the field he is involved in.If he had a more vigorous partner, then he, the dean, would have more confidence in the face of a cross-border medical group like Neo Company.
Chen Qun's surgical technique alone can be said to be No. 1 in the field of surgery in the world, including the field of minimally invasive surgery. Charlotte Hospital must cooperate with Chen Qun to treat those top figures. This is the relationship between him and Chen Qunguang. Already share a common interest base.Now coupled with Chen Qun's scientific research ability, even if he is not the world's best, his luck is also the world's number one, which is enough to use this cover to bargain from other multinational medical groups and get more benefits.
The reason why Chen Qun did this was to lead the Xiangyun Hospital he worked for to become a world-class hospital. Even with a genius like Chen Qun and a talented team, with the medical level of the Far East, if he wanted to catch up with and surpass Xia Lute, at least needs Chen to fight for a lifetime, and there is no threat to him now and in the future, so he naturally raised his hand in favor.
(End of this chapter)
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