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Chapter 186 Methyl Ethyl Ketone Inhibitors
Chapter 186 Methyl Ethyl Ketone Inhibitors

Although she had been stabbed with several needles, Qi Hong was still full of energy, and directly rejected Liang Shaoming's suggestion to continue to rest and observe, and followed Huang Haitao with Chen Qun and the others, and rushed towards the laboratory together.

Due to the identification of the toxin, other requirements have been greatly reduced. Although the hospital's first-level emergency response has not been lifted, all medical staff are no longer so worried.

After all, any unknown toxins and viruses are the most dangerous, and the known ones are not so terrible.Because there are mature solutions.

When Chen Qun and the others came to the laboratory, they saw several colleagues who had not rested and were busy in the room, using zebrafish as a live experimental carrier to conduct target pathological verification of the mutated gene.

Seeing that Huang Haitao's complexion improved a lot, the boys immediately came up to him and reported on the progress. They even forgot to inquire about Huang Haitao's condition.

"Mr. Huang, after we identified the toxin, we contacted the records of gold poisoning and cesium poisoning, speculating that the gene mutation that has appeared now leads to respiratory failure. The main reason is the production of an enzyme called kinase, which leads to the excessive growth of human cells and produces A lot of fluid."

"At the same time, gold and sodium sulfide will lead to the decline of the human immune system, stimulate the lymphatic system to swell, block the respiratory tract, and the lesions caused by kinases will make the condition very serious. However, there are also successful treatment options abroad. Now we need to What we do is to find out a suitable material medicine to prescribe the right medicine.”

Huang Haitao frowned slightly, "For those who don't know much about genetics, can you simply tell me what the correct solution is?"

Qi Hong answered this question with a look of embarrassment, "Using methyl ethyl ketone inhibitors is the most common method today."

Huang Haitao waved his hand, "Just use it right away. Could it be that the hospital here doesn't have this kind of inhibitor? That's easy to handle. I'll figure out a way."

Tie Jun quickly added next to him, "Mr. Huang, it's not that our lab doesn't have any, but that there are too many of them, a total of 43 types. Each type targets different gene segments and has different consequences. The same. Each will cause different side effects, as long as the wrong use, the patient's condition will be exacerbated immediately, and even death."

Huang Haitao tilted his head and asked strangely. "Then let's screen them all, won't we be able to find the right antidote?"

"Theoretically speaking, the gene mutation caused by each patient is different, that is, the gene mutation of Mr. Huang may be of a completely different type from the gene mutation of Chen Qun. In other words, every patient, More than 40 experiments are required, and if the target is not in these 43 types, we have to continue to synthesize new inhibitors to cope with new gene mutations."

Qi Hong quickly added an explanation at the side, so that the young experts in intractable diseases who are not strong in genetics can understand the troublesome and serious nature of the matter.

"Show me your 43 inhibitors, what are the side effects?"

Huang Haitao rubbed his head, looking at the vats of medicinal zebrafish in front of him with great nerves.Knowing that if each patient undergoes 43 kinds of pathological tests at the same time, it is very likely that the patient will die early before the results come out.

Qi Hong quickly passed the tablet over, Huang Haitao looked at it twice, feeling more and more headache. Most of the 43 medicines are not translated, they are all written in English, only a few of them have been translated.It seems that it was Qi Hong's impromptu translation, and the grammar and sentence structure are still a bit messy, but I can barely understand it.

After carefully scanning the translated eight or nine medicines, Huang Haitao handed the tablet to Chen Qun, "Xiao Chen, if you choose one of these 43 medicines, which one is the most suitable?"

Chen Qun glanced at it, then used the time-pause skill at once, entered the system space again, and looked at the results of the genetic mutation analyzed by the system. What answer did it give?
As soon as he entered the system space, he saw a structural formula with more than 300 genomes appearing on the big screen, and three corresponding drug names were given next to it.

But what reassured Chen Qun the most was that this broken system was taking the first patient as a sample to extract the immune antibodies in his body, and the molecular formula had already analyzed more than ten groups of structural molecular components.

Sure enough, targeted drugs are the kingly way. Otherwise, one patient should be analyzed once. With the modern technology level, it would not be possible to analyze hundreds of patients separately before prescribing the right medicine.

He withdrew from the space system in a blink of an eye, pointing to the first medicine on the tablet.

"My foundation is worse than that of Mr. Huang. If I were to choose. Then I would choose the first drug, selumetinib. After all, it has the least side effects. Besides, this is a clinical trial that has been translated into Chinese. medicine, which means that it has the widest applicability and can be effective for most situations.”

Sometimes it is so simple to prescribe the right medicine. It is very likely that the first medicine that comes to mind is an effective medicine for treating the condition.Of course, Chen Qun would not disclose the inside story that he cheated and knew the truth, so he could only make up and find reasons to explain things as always.

Huang Haitao did not have any doubts about Chen Qun's luck, so he waved his hand immediately,
"Well, you two, Zhou Lin and Ouyang Yang, went to the intensive care unit, first used selumetinib for patient zero, and also used this drug for several other critically ill patients who failed to respond to specific drugs, just the dose Halved. You continue to conduct experiments, Qi Hong and Chen Qun will join me first to report the progress to Dean Liu."

Tie Jun, who was observing under a microscope, suddenly said, "Cross SL-327 off the drug list, I saw two, no, three tumors on the zebrafish."

Chen Qun glanced at dozens of cheerful zebrafish swimming in a large tank in the distance, and asked in surprise.

"Are these samples or test items to be injected with drugs?"

"No, that's a sample of a mild patient's serum antibody test, and the results will be known in two hours. We injected the patient's serum not only on zebrafish, but also on five mice, two rabbits, and four pigeons. I took the same serum to see if there is any effect. But looking at the symptoms now, at least it shows that the serum of the recovered patient has a good immune effect."

Qi Hong answered Chen Qun's question beside her. It turned out that after seeing two poisoned patients recover, all symptoms disappeared.Knowing that their bodies had developed antibodies against the radioactive element cesium, their serum was immediately extracted and injected into zebrafish for pathological experiments.Of course, this was done by her own initiative and commanding the three boys.

(End of this chapter)