I Don’t Want to Win Lying Down

The following two special guests are invited!

A pioneer in the field of gene editing, Professor Burton Richard of the Department of Biology at Stanford University.

moment,

Professor Burton Richard came to the stage, but he was angry that he was asked to come on stage first. Basically, the more important the person on this occasion, the more he would appear at the end. However, he never expected that he would be in Xu Mang's In front, there are only two guests.

Next is an authority in the field of physics, a Nobel Prize winner in physics...Professor Xu Mang!

As soon as the voice fell,

Xu Mang came to the stage with his own smile, and his seat was next to Professor Burton Richard, a few meters away from the supporters. It was a very standard conversation mode. It seemed that the organizers were very careful. , Of course... There may be ulterior motives, who knows what tricks the United States is playing.

Looking at Xu Mang with a calm face on the stage, and a group of foreign experts in the field of gene editing under the stage, he felt very uncomfortable all over. At the forefront of gene editing.

After that, there was a very boring greeting session. Xu Mang was completely indifferent to this session. He asked and answered each sentence, and the whole state was incompatible with this elite forum meeting. For a while, the smell of salty fish permeated the entire venue.

Professor Burton Richard...what's your view on the future of the gene editing field? the supporter asked.

The current situation is pretty good. In this field of fierce global competition, American scientists have begun to lead the world. Professor Burton Richard said seriously: Recently, our research team at Stanford University discovered that the existing gene editing technology While modifying the DNA, a large number of ribonucleic acids will be accidentally injured.

Based on this discovery, we have invented a gene editing technology that does not cause accidental injury, with a success rate of over 97%, making gene editing safer and more efficient, and providing an important safety guarantee for its clinical application.

words fall,

Professor Burton Richard glanced at the silent Xu Mang, and asked curiously, Does Professor Xu Mang have any opinion on this technology we discovered?

ah?

Oh...it's a pretty good technology. Xu Mang nodded with a confused face, but his tone was extremely serious: Work hard and strive to be on an equal footing with us in the past two years. I will be number one in the world. Watching you work hard.

Professor Burton Richard: @#￥%...!

furious!

So arrogant!

Not only was Professor Burton Richard very angry, but many European and American gene editing experts present felt burning pain on their faces.

Ahem!

Then what...Professor Burton Richard, can you tell me more about this technology? The host hastily changed the topic. He talked about the possible situations, including Xu Mang mocking others.

good!

At present, we have applied for a patent for it and promoted its clinical and industrial transformation. Professor Burton Richard said earnestly: Venture investment has been involved, hoping to accelerate the transformation of basic research to clinical and industrial.

Yeah?

May I ask which diseases are the clinical aspects? the supporter asked.

Professor Burton Richard coughed lightly, and said seriously: There are more than 7,000 rare diseases plaguing human beings around the world, and about 80% of them are single-gene genetic diseases, such as thalassemia, blood Friendship disease, macular degeneration, hereditary deafness, etc.”

Theoretically, gene editing technology can easily correct these natural mistakes and restore health to hundreds of millions of patients. Professor Burton Richard continued: But so far, due to the uncertainty of safety, , only a handful of two or three gene editing technologies have reached the stage of clinical trials.

At this time,

Xu Mang raised his head and glanced at Burton Richard beside him. Although this guy was very annoying, his ideals were noble.

To cure a genetic disease, it is often necessary to edit the genes of trillions of adult cells. If the editing is not precise enough, cell errors will cause risks such as cancer. Professor Burton Richard said seriously: Most genes Editing techniques use viruses as carriers, and then send editing tools to the inside of cells.

Although there are navigation molecules, there will still be off-target phenomena. Even the latest editing tool discovered by Professor Xu Mang will also off-target, although he himself said that it will not. Professor Burton Richard smiled lightly: I A fatal flaw of the CRISPR-C2c1 gene editing system has been discovered.

!!!

!!!

!!!

moment,

The scene became lively, and everyone's eyes widened, looking at Professor Burton Richard expectantly.

As for the fatal flaw of Professor Xu Mang's CRISPR-C2c1 gene editing system, I will mention it later, and now I will continue to talk about the technology we discovered at Stanford University. Professor Burton Richard said with a smile: Please be patient and don't be impatient. .”

Xu Mang: (﹃_﹃)

What the hell,

Whether his ideals are lofty or not is none of my business... I will kill you later!

Human DNA has a total of more than three billion bases, one percent of which are gene fragments, and many of the rest record information about non-coding ribonucleic acid and other molecules involved in life activities. Burton Rich Professor De said: We have established a detection system.

And then the single-base gene editing technology that was supposed to be safe can cause 20 times the normal gene mutation. Professor Burton Richard said: We have developed a gene editing technology that will not cause accidental injury.

Coding ribonucleic acid can directly produce protein, and it is also a second delivery tool for turning DNA into protein. The change may directly affect life activities. Professor Burton Richard continued: Now the progress is very impressive.

words fall,

There was applause everywhere, and almost everyone was excited about it. Finally, there is a technology comparable to the CRISPR-C2c1 gene editing system, and...the CRISPR-C2c1 gene editing system has huge flaws, basically Huaguo The number one in the world cannot be kept.

if only...

Professor Burton Richard declared that there was absolutely no room for redemption.

Professor Xu Mang?

Do you have any opinion on the technology developed by Professor Burton Richard's team? the host asked.

view?

What can you think.

Xu Mang said listlessly: It's not bad, but...I really want to know what is the fatal flaw of the CRISPR-C2c1 gene editing system.

good!

Since Professor Xu Mang wants to know so much, I will announce it. Professor Burton Richard said with a smile on his face: Although the success rate of the CRISPR-C2c1 gene editing system is very high, and it can be done with AI 100% success rate, but... some individual genomes will have errors, even AI can't detect it.

Our technology must be used!

words fall,

Professor Burton Richard took out a data disk, handed it to the host, and said, Please use the display on the back to display the contents inside.

just for a moment,

Everyone, including Xu Mang, saw the following sets of data.

This is based on the data calculated by our team based on the existing public CRISPR-C2c1 gene editing system. In the face of premature aging syndrome and hematuria, the failure rate is as high as 15%, which is intolerable. !

But please don't worry!

The technology developed by our Stanford University has a very significant effect on genetic diseases and can make up for the defects caused by the CRISPR-C2c1 gene editing system. Professor Burton Richard said seriously.

at this time,

Xu Mang turned his back to everyone, looked up at the huge display screen in front of him, and fell into a moment of confusion.

Why?

How did you forget these two?

Xu Mang frowned and kept thinking about why these two genes were forgotten. Finally, he thought of the reason. It was a problem with the database... It seemed that the data of these two genes had not been recorded.

Professor Xu?

Professor Xu?

Seeing Xu Mang staring at the screen in a daze, the host hurriedly asked him, Are you surprised that the CRISPR-C2c1 gene editing system you developed has such an error?

Well...

No.

Science is continuous exploration and self-denial. The database relied on by the CRISPR-C2c1 gene editing system does not include these two genes. After all, these two genes are too rare, but... this is not a reason. Xu Mang said seriously: I admit that the CRISPR-C2c1 gene editing system has huge defects in front of these two genes.

...

...

at this time,

Xiao Zheng and Xiao Yi were particularly unconvinced. Sure enough, Professor Xu Mang followed the advice of others. This group of hateful Americans pointed to the flaws in Professor Xu Mang's discovery with their only mistake. What are you kidding about? Why don't they think about the significant improvement in other genes besides these two.

hateful!

It's disgusting!

This group of people is shameless! Xiao Zheng said angrily: Professor Xu Mang's CRISPR-C2c1 gene editing system, after our experimental test, has a very, very high success rate. Just take these two special genes as an example. thing, damn it... damn it!

No!

Stanford University's technology is still under development, so you dare to show it off? Xiao Yi said angrily, I'm so pissed off!

angry to angry,

But what to do after that?

Xiao Zheng and Xiao Yi were quite worried about Xu Mang. At present, Professor Xu Mang had been torn open, and these people would definitely sprinkle salt on the wound.

Ahem!

host?

Should it be me next? Xu Mang said blankly, Should I show it to everyone?

???

???

???

Everyone looked at Xu Mang at the same time, with worry and anticipation in their eyes.

 …

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