I Have a Research Support System

In Zhang Jiang's laboratory, Han Jiaying stood by the metal medicine cabinet, Brother, the solvent we used for the reaction is imidazole, where is it, why can't I find it?

Xu Qiu was preparing the glass instrument for the experiment. He recalled it and said, Before the holiday, I seem to have put it on the left side of the second floor of the reagent cabinet.

But isn't the second layer a solid reagent? Imidazole is a solvent, so it should be a liquid, right? Han Jiaying asked suspiciously.

Solid medicine can also be used as a solvent. If I remember correctly, imidazole should be packaged in a 100-gram box of Sinopharm. Xu Qiu said, he ordered this medicine before, so he still has some impressions.

Hmm... I'll look for it, Han Jiaying continued to rummage while searching, Imidazole, imidazole, I found it. It's really a solid. Its melting point is 89-91 degrees Celsius.

Just find it, Xu Qiu explained: Although imidazole is solid at room temperature, it can be turned into a liquid as long as it is heated to melt. It can be used as a solvent. The temperature for this reaction is set at 120 degrees Celsius, which is why. Although the task of summarizing the experiment was given to the school girl before, the preparation work that should be done has not been left behind.

Afterwards, Xu Qiu said solemnly: Before the experiment, if unfamiliar reagents are involved, you must go to the MSDS to check the basic physical properties, such as whether it is toxic, melting point, boiling point, etc., and whether there are other dangers, such as explosive, strong oxidation. , strong corrosiveness, etc., even if it saves trouble, you can check Qiandu Encyclopedia, for example, imidazole is toxic to a certain extent, but it cannot volatilize, as long as it is not eaten by mistake, it will be fine.”

Yeah, I know. Han Jiaying nodded like a chicken pecking at rice.

After the two prepared the glass instruments and medicines in place, they started the experiment.

The raw materials are perylenetetracarboxylic dianhydride and various amines, and the solvent is imidazole, which are relatively low-cost chemical raw materials.

For example, perylene tetracarboxylic dianhydride costs more than a hundred for 25 grams, so Xu Qiu bought two bottles at once.

After calibrating the balance, he carefully weighed the red solid powdered perylenetetracarboxylic dianhydride, and complained: This time, 5 grams of raw materials can be added to each reaction, and finally there is no need to dig and search like the previous polymerization reaction. Search, only one or two hundred milligrams of reactants are injected each time.

Yes, Han Jiaying was operating in front of another balance, and I think the reaction yield is quite high, about 90%. One synthesis should last for a long time.

If you use it directly, it can be used for a long time, and you can even use it after graduation. After all, we only need about 10 mg of the solution for the device at a time. Xu Qiu smiled and said:

But if the synthesis continues as a raw material, it is not necessarily true. Even if the yield is 90% each time, the total yield after the five-step reaction is only 60%, not to mention that the yield of most steps cannot Maintain more than 90%, and some may be less than 50%.

Han Jiaying hummed, and then said: By the way, brother, we will do post-reaction processing later, shall we use liquid chromatography?

Of course, for small molecule materials, we can't spare the 'passing through the column', which is the step of liquid chromatography. Xu Qiu said.

It's so troublesome to say that in the previous synthetic chemistry experiment class, the most annoying experiment was going through the pillar. Han Jiaying said.

Chen Wanqing interjected: Our liquid chromatograph is quite advanced. Teacher Wei bought it for the purpose of making a PDI system. It cost more than 100,000 yuan. However, it fell to dust after only a few times of use... The more she spoke, the lower her voice was, obviously thinking of a dark history before.

One hundred thousand yuan? It's so expensive, so it should have a higher degree of automation. Xu Qiu glanced at the senior sister, her experiment progress was a little slower, a beat slower than theirs.

Yes, it's fully automatic. At that time, Mr. Wei bought it according to his preparation in the beautiful country laboratory. Chen Wanqing also walked to the side of the scale and continued:

It will run by itself after setting the program, but people can't leave during the process of passing the pillars, which is quite troublesome.

Xu Qiu nodded. He copied the senior sister's proficiency, liquid chromatography, only the third-order 50%, and he spent some points to upgrade to the fifth-order 0%.

Then he focused on two tasks, while continuing to do experiments, while watching the system video to learn the operation method of this liquid chromatograph.

The response to today's submission is not as strict as the previous polymerization reaction.

You only need to put the two raw materials and the solvent together, find a clean round bottom flask, heat and stir, and because the boiling point of the solvent imidazole is very high, above 200 degrees Celsius, there is no need to set up a reflux device, so even the condenser, circulation Water is not needed.

In addition, this reaction has relatively loose requirements on the ratio of materials. It is not necessary to strictly abide by 1:1, as long as the amine reagent in it is excessive, of course, it must also be excessive, otherwise there may be two main products in the final reaction, which can be separated. It will be more troublesome.

After Xu Qiu weighed two solid reagents, perylenetetracarboxylic dianhydride and imidazole, he took the two amine reagents, 3-aminopentane and 6-aminoundecane, into the fume hood.

The several amines they used were liquid at normal temperature, and were volatile and toxic. Therefore, he chose to operate in a fume hood, and used a syringe to measure the volume to estimate its mass, and directly added it to the reaction bottle.

Since one perylenetetracarboxylic dianhydride molecule can react with two amine molecules, Xu Qiu set the material ratio at 1:2.5 and the reaction time at 24 hours, so that the two can fully react.

Xu Qiu did not forget to remind the school girl: Add amine reagents in the fume hood, and pull the door of the fume hood to the bottom to prevent leakage. After all, none of the three of them wore gas masks, and the protection of ordinary disposable activated carbon masks Ability is relatively limited.

Okay. Han Jiaying followed suit.

...

Soon, Xu Qiu voted for two responses. ‘I feel that the response time is very fast this time, but the reaction time is 24 hours. It would be great if it could be accelerated like in the simulation laboratory in reality, but unfortunately it cannot. '

After starting the heating and stirring function, as the temperature rises, you can see that the solid matter in the round bottom flask is melting and glowing red, as if something indescribable is being refined.

After a while, Han Jiaying's two responses were completed, and she called out: Brother, come and help me, my responses are okay.

How can you see it with the naked eye? Even though he said that, Xu Qiu still walked over. The state of the school girl's reaction container was similar to his. Test you, what is the core of this reaction, what do you think?

Hmm... Han Jiaying thought for a while, and then said, Is it the material ratio?

That's right, as long as the amines are added in excess, basically there will be no problem with this reaction, Xu Qiu glanced at Chen Wanqing who was still doing the experiment, and continued: Let's go, let's tidy up the laboratory, and then put the The glass instruments accumulated in the laboratory alkali tanks are all cleaned.

Okay, Han Jiaying nodded, Then I'll clean up the lab.

Yeah. Xu Qiu walked towards the sink, and he put the alkali tank in the cabinet under the sink. He first turned on the faucet, and then put a basin under the running water.

Then take out the alkali tank, carefully take out the various glass instruments soaked in it with long tweezers, pour out the lye inside, and then rinse it under the running water, and finally transfer all kinds of bottles and jars to ultrasonic cleaning instrument.

The next step is to wash with detergent for two rounds and tap water for one round. After rinsing, drain the water and put it in an oven to dry.

In this way, most of the glass instruments can be washed clean, and a few of them that are not cleaned can be brushed with a brush and thrown back to the alkali tank for remaking. After another round, if it is really not clean, it is discarded directly.

This cleaning process lasted for a long time, but it took up the scattered time of the experiment, and it was not in a hurry, even if it could not be finished in a day, it was not very important.

...

After finishing today's experiment, the three returned to A501 to rest.

Xu Qiu had left his mobile phone in the office before, and there was a missed call at this time.

It was an unfamiliar number, but it was not marked as a nuisance call, so he called back, and the call was connected soon.

Hello.

Hello, I am Qiu Heming, the sales manager of HORIBA Company. Mr. Wei contacted me before, saying that your research group intends to purchase a TRPL instrument, let me contact you, or we can add a WeChat to talk about it, and I can give it to you. Send me the brochures and quotations of our company's products.

Okay, I have the same WeChat account as my mobile phone.

Then I won't bother you any more, bye.

Bye-Bye.

According to the voice, Qiu Heming is a middle-aged uncle, and he speaks in a leisurely manner.

Not long after, Xu Qiu received Qiu Heming's WeChat verification message, and the WeChat name used was his real name.

After passing, the other party sent a few PDF files, Xu Qiu downloaded them, then sat on the sofa, called the seniors and juniors over, and sat next to him to study together.

Seeing the picture of the instrument on the home page, Han Jiaying said: The TRPL instrument sent by Dr. Qiu looks much smaller than the one we used for testing at Sioux City University last time. I remember that Mr. Hou Kaihua's is also from HORIBA. .”

Well, maybe theirs is an early product, and the technology has been iterated now. Xu Qiu paused and said: It's not important, such an expensive instrument, they must have adjusted it well, and then the data is normal after we test it. They will be paid, and if there is a problem with the equipment, they will not receive money.

He flipped through the PDF file backwards. The whole TRPL instrument is composed of three parts: the sample chamber, the detector, and the laser generator.

The detector is fixed. We don't need to worry about that. Now there are two issues to consider. One is the sample compartment and the other is the laser. Let's look at the sample compartment first. Xu Qiu said:

My suggestion is to choose a larger one, such as this one with a side length of 60 cm, because it may involve modification of the optical path, such as adding filters, light reduction mirrors, etc. If it is larger, the operating space will be larger. What do you think?

Chen Wanqing quickly raised an objection: There is not much space in our Handan laboratory. I just saw that TRPL's detector has three parts, each about 15*30*40 cubic centimeters. If the sample compartment is also about 30 centimeters in length , you can also find a corner and place it vertically, but if the sample compartment is too large, there is a high probability that it won’t fit, so you can’t buy it and put it in Zhang Jiang’s laboratory, it’s so inconvenient.”

That's a problem. Xu Qiu was lost in thought.

The minimum size in the manual is 45 cm side length, and the 30 cm square sample cabin is not listed in the manual. Whether it can be made or not is a question.

Do you want to make do with 45 cm?

But the 60cm sample cabin looks more and more pleasing to the eye.

But it is indeed as the senior sister said, such a large instrument cannot fit in the Handan Laboratory, and there are two glove boxes and more than a dozen instruments, large and small, squeezed into the space of more than 20 square meters.

The available space on the spare test bench is only about 30 centimeters in depth, mainly because most of the experiments are performed in the glove box, which is not as demanding as the synthetic laboratory for the test bench.

what can we do about it?

Suddenly, Xu Qiu had an idea and said:

I remember that there is a utility room over Teacher Wei's office. There seems to be an empty desk. You say...

If you go to mention it, I agree with both hands and feet, and choose a 60cm sample cabin.

Me too.

Hey, what's the use of you two, I'll go back and talk to him later. Xu Qiu sighed and continued:

Then there is the problem of lasers, ranging from more than 300 nanometers to more than 700 nanometers. I think you should buy two, one is about 500 nanometers, and the other is about 700 nanometers.

This can just take into account the light absorption range of most organic photovoltaic materials, and the light absorption range of perovskite materials is similar, so they can be used together.

I have no objection to that. Chen Wanqing nodded and said, Why don't you take a look at the quotation before making a decision?

Okay, Xu Qiu saw that the junior had no other opinions, so he opened the quotation directly and said, There is no problem with the wavelength difference of tens of nanometers. Try to choose the cheapest one, and save some money for the team.

The three finally chose 465nm and 695nm lasers. The price of one is 70,000 and the other is 52,000. The price of the sample chamber and the detector is fixed, which adds up to a little over 70,000. Of course, the most valuable thing is the detector. , The sample compartment is an iron lump.

Afterwards, Xu Qiu sent the results of their discussion to Qiu Heming and asked for some discounts.

In the end, the whole equipment added up to a total of 188,000. Qiu Heming's efficiency was very high, and the quotation was made in less than half an hour, and now we are waiting for Teacher Wei to make a final decision.

Chen Wanqing's response was to shut down at night, but Xu Qiu's and Han Jiaying's didn't. The three of them made up their minds and decided to stay in Zhangjiang, write a review together, and take the last school bus back at night.

At about 5:30, Chen Wanqing received a call from Teacher Wei, mainly asking about their experiments.

‘Perhaps it’s because Handan suddenly lost three people, and Teacher Wei misses them a little bit? '

Xu Qiu was speculating about Mr. Wei's intention to investigate the post, when he suddenly heard Chen Wanqing say, About TRPL, Xu Qiu has something to report.

Then he had a mobile phone in his hand.

Confused.

Thank you Lord Fengyun for rewarding 1800 starting coins, and book friend 160817091132751 for rewarding 100 starting coins. There is no manuscript saved, and the second update today will be postponed.