I Have a Research Support System

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Xu Qiu and Han Jiaying had a wonderful Saturday.

On Sunday, the two switched back to work mode again, eating in the cafeteria at noon while chatting about the experimental plan.

Han Jiaying took the initiative to open the topic: The monomer units of the PBDB-T series have been notified by Shencheng that they are in stock. I bought a total of 500 mg. It has been shipped and should arrive this week.

After a pause, the school girl continued: My second-generation H22 series donor materials, combined with the school sister's system, have a maximum efficiency of 7.3%. Compared with the first-generation H series donor materials, the improvement in efficiency is average. Generally speaking, I will consider developing the third generation of H-series molecules.

Xu Qiu gave a hmm and replied: There are already fluorine atoms on the FTAZ unit, and there are no other sites that can be introduced. At present, it can only be optimized for the BDT unit. Let's continue to optimize the side chain...

Xu Qiu picked up a dry-pot chicken nugget, put it into his mouth, thought for a moment, and said, The thiophene unit on the side chain remains. For heteroatoms, sulfur and oxygen have been tried. You can try the silane side chain, of course. It is also possible to introduce fluorine atoms on the BDT unit.

Okay~ Han Jiaying nodded and said, I only thought of introducing fluorine atoms before, because there are corresponding units sold in Shencheng, but they are a little more expensive. For silane side chains, we need to synthesize them ourselves. It’s not difficult, these two structures are tentatively designated as H3x and H4x systems.”

From the perspective of synthesis, it is really not difficult. I should have given you the literature before. It is necessary to use tin reagents and low-temperature reactions of n-butyllithium. Trimethyltin on both ends of BDT has a certain Dangerous. Xu Qiu continued:

Similarly, for the PBDB-T system, if you want to develop new materials in the later stage, you also need to synthesize monomer units yourself. This structure can introduce more group sites and can be optimized to be more perfect.

I will pay attention to the safety of the experiment. Han Jiaying patted her chest to reassure, and after a while, she suddenly said: By the way, senior brother, have you heard that the AM article by senior sister is the opinion of the IDT-ICIN system? I came back and said that it is recommended to switch from AM to AEM.

When did it happen? Xu Qiu asked in surprise. He really didn't know about this matter. Usually, the news in the article was that he was more informed than the junior girl. Unexpectedly, it was the junior sister who told him the news this time.

When I went to ask my sister about the performance of the device this morning, she casually mentioned it to me. Han Jiaying explained.

It turned out to be like this. Senior sister's luck is a little bit bad. Xu Qiu stroked the non-existent beard on his chin, and analyzed: It is estimated that Teacher Wei probably agreed to the editor's request to resubmit. Modifications can be accepted directly without reviewing the manuscript again.

In the afternoon, material one 216.

Xu Qiu confirmed his previous thoughts from Chen Wanqing's mouth. Sure enough, Wei Xingsi compromised and directly agreed to the request to switch without appealing to the editor.

I came back with comments on Friday, and that night, the senior sister corrected the comments and text of the article and returned to the editor.

In fact, as a sub-journal of AM, AEM is similar to the big sub-journals of Nature and Nature. Although the grade is slightly lower, it is not too low. It is still acceptable for AM to AEM, if If it's AFM or even AELM, it's a bit of a loss, and Teacher Wei probably won't follow.

It's just that the AM that my senior has been thinking about all the time, now it's done again.

The key point is that Chen Wanqing is currently in her second year of PhD, and she will officially enter her third year of PhD in the new semester. She needs to sort out her graduation thesis and look for a job at the same time. The time for doing experiments is definitely not as long as it is now. Time is running out.

Now in the field of organic photovoltaics, because the beautiful country has reduced the relevant research funding, it is somewhat difficult to go abroad to find a postdoctoral fellow.

Chen Wanqing is still debating whether to look for a postgraduate degree in another direction, or to develop in the industry, or to change careers, looking for opportunities to go to a big factory like Warwick. Every year, there are many people from the Materials Department of Shanghai University of Magic who go to Warwick. Hard work is still very promising, of course, overtime is definitely inevitable.

However, the work intensity of Mr. Wei's research group should theoretically exceed that of Warwick...

In the academic circle, 996+ has long been commonplace in research groups with a relatively PUSH atmosphere, and it is still legal 996+.

Reporter: How can you let your students 996?

Mentor: Oh, they're all voluntary.

Reporter: It doesn't work voluntarily, according to the Labor Law, blah blah blah...

Tutor: Oh, you said Labor Law, they are students, they are studying, not working, if you don't believe me, look at the current high school students, the morning self-study starts at 6:30 in the morning, and the evening self-study ends at 10:00 in the evening. Make up classes on Sunday, which is more serious than 996, isn't it a normal phenomenon?

Reporter: It seems to make sense, but there is something wrong...

Instructor: It must make sense, how can the student's 996 be called 996?

Two days later, Chen Wanqing has accepted the fact that the article has been transferred to AEM. After all, AEM is also a good journal in the first district, and she can finally wash away her past nickname of killer in the second district.

As a result, the senior sister regained her fighting spirit and discussed with Xu Qiu the next experimental plan.

Xu Qiu first made an opinion: The name of IDT-T(EH)-ICIN is really too long, how about an abbreviation?

Chen Wanqing smiled and said: I have already noticed this when I was writing the article. I have already thought of its abbreviation. It is called IEIC, where IDT is abbreviated as 'I' and T(EH) is abbreviated as 'E'. ICIN is called 'IC' for short, what do you think, Xu Qiu?

I have no objection. Xu Qiu nodded and said, Sister, you can decide for yourself. Anyway, we are the only group working on the subdivision of ICIN, and we are not afraid of duplication with other people's names.

Chen Wanqing opened a PPT file on the desktop and said, Help me see the three molecules I designed.

The three molecules of the senior sister were named IEICF, IEICO, and IEICS by her.

Xu Qiu looked at the reaction steps and commented: The first IEICF is to introduce fluorine atoms into the thiophene unit. This is relatively simple. You can directly purchase the corresponding units and then synthesize them. However, in this case, the fluorine atoms occupy The position of the original alkyl side chain is lost, it is difficult to introduce side chains, and the solubility may be poor... I am not very optimistic about this molecule.

Yeah, Chen Wanqing nodded, changed it on the PPT, and said, Then I'll make this system at the end. Let's see how the other two structures look.

Xu Qiu continued to check and found that IEICO and IEICS have similar structures. Oxygen and sulfur heteroatoms were respectively introduced into thiophene. The synthesis route is slightly more complicated and requires five steps of reaction.

In the first step, methoxy/methylthio substituted thiophene, under the conditions of isooctyl alcohol and p-toluenesulfonic acid, introduces the side chain of 2-ethylhexyl (EH) to replace the methyl position to form T (OEH ) and T(SEH) units.

In the second step, the brominated reagent, N-bromosuccinimide (NBS), reacts with the product of the first step to obtain monobromosubstituted products, T(OEH)-Br and T(SEH)-Br.

The third step is to react with n-butyllithium and DMF in two steps, and form an aldehyde group on the other side of thiophene to obtain Br-T(OEH)-CHO and Br-T(SEH)-CHO.

In the fourth step, a Stille reaction occurs with the IDT substituted with bistrimethyltin to generate two OHC-T-IDT-T-CHO structures with different side chains.

The fifth step is to react with ICIN to generate the final products IEICO and IEICS.

There is nothing wrong with the overall route, only the first and second reactions are new, and they are not too difficult. Xu Qiu commented, it seems that the senior has grown a lot.

That's good. I'll do the synthesis when the IEIC system data at hand is complete. After listening to Xu Qiu's words, Chen Wanqing felt very at ease, and asked casually: By the way, Xu Qiu, your synthesis last week was pretty smooth. ?”

Although the product has not been characterized by NMR and elemental analysis, judging from the properties of the product, it should all be successful. Xu Qiu paused and said:

Now we have obtained three derivatives of ICIN, which are dichloro, difluoro and dimethyl substituted, and the output is more than 5 grams. You can also use these kinds of ICIN derivatives in your IEIC system, IDTT, FND The unit has also been synthesized, followed by the formylation reaction and the final D/A conjugation reaction.

The progress is pretty fast. Chen Wanqing said with a smile.

After chatting with the senior sister again, Xu Qiu sat in his seat and began to think about today's experiment arrangements.

If you go to Zhangjiang, the experiment time is too short, and you have to come back for a group meeting on Monday...

The new material has not yet been synthesized, and it seems that Handan has no experiments to do...

No articles to write either...

It seems to be a good day for fishing!

Just as Xu Qiu was thinking, he suddenly saw Mr. Wei appearing at the door of 216, staring at him with burning eyes.