Science and Technology Library

Chen Mo's question made everyone on the field quiet and a little embarrassed.They want to treat patients quickly, but they ignore that they are doing research now.

They all know that researching this kind of thing may suddenly succeed tomorrow, or it may not be successful after they enter the coffin. It mainly depends on whether the researchers can find the node of the technological breakthrough.

If you can't find the key, no matter how much time you give it, it will be in vain. If you can find it, the road ahead will be smooth.

"Customized vaccine technology is not yet mature, and the development speed may be slower than other drugs." A gray-haired expert said: "Why don't you continue to study HX3, academician Chen, the improved HX3 drug has successfully suppressed Redman virus, and then do it again." Improvements may not necessarily eliminate the virus.”

This remark made other medical experts nod their heads.

The improved HX3 agent has achieved good results, at least it has an effect on Reedman virus, which is a sure direction.

"HX3 is just a protease inhibitor. Its effect is limited to inhibiting the replication of viral proteins and allowing the virus to enter a dormant period. It cannot inactivate the virus itself, otherwise its function is not to reduce the activity of the virus. If it can really clear the virus, one From the beginning, the direction of my improvement is not to suppress its metabolism." Chen Mo said.

HX3 was developed by him with the information provided to Haixing Company. He knows all the functions and effects clearly. No matter how it is modified, its function is to reduce the activity of the virus, and its essence cannot be changed.

"But custom vaccine technology, this technology is full of too many uncertainties."

"You have determined the research direction of the special drug for Redman virus. Which direction is correct?" Chen Mo asked.

All the researchers on the field were breathless and unable to answer.

"Are you really determined to study a customized vaccine?" Shi Hongtu asked.

He is the team leader of the medical team, and his main task is to find a specific medicine against Reedman virus as soon as possible. Although he does not agree with Chen Mo's research on customized vaccines, he cannot influence Chen Mo's thoughts.

"Yes." Chen Mo nodded.

The scene fell into silence again, and they had no good solution to Chen Mo's insistence.

"Let me tell you what I think."

Wu Bing spoke, and everyone on the field looked at her.As one of the youngest researchers in the medical team, Wu Bing's ability is not inferior to others, so his words still have a lot of weight.

"Academician Chen formed an independent team to research customized vaccine technology, while others researched reverse enzyme inhibitors. In this way, they were divided into two groups and went hand in hand. At least there was one more possibility in the selection, so as not to have a dead end."

Shi Hongtu sighed. Judging by Chen Mo's posture, it is impossible to give up the research direction of customized antibodies. No matter how much they say, it will be useless.Chen Mo has the right to freely choose any direction of research without restriction, which was agreed when Chen Mo joined the group.

Now Chen Mo is just informing them, not asking for their opinions.

"Since Academician Chen insists, according to what Academician Wu said, the team led by Academician Chen will study customized vaccine technology, and the others will study reverse enzyme inhibitors according to the original research plan."

Shi Hongtu made the final conclusion.

"Who is willing to join Academician Chen's group to study customized vaccine technology?"

Many experts on the field did not speak. Customized vaccines are usually researched. If they come out, this is a cross-age vaccine technology.But in the time of the virus outbreak, this is not a good choice.

"It's still the same as before. My team and I will join Academician Chen's group for research." Wu Bing said.

Chen Mo was not surprised by this situation, as he expected, he just nodded slightly to Wu Bing.

"Okay, today's meeting is over. Everyone continues to carry out research. If there is any progress, report it and discuss it immediately. The current epidemic situation outside is not optimistic."

Shi Hongtu's last sentence made the atmosphere heavy.

……

In a small office of the institute, six researchers sat quietly.

The six members are members of Wu Bing's team, four men and two women, all of whom look young, all around 30 years old, and are the team with the youngest average age in the medical team.They are all some outstanding students of the medical academicians of the Academy of Sciences, or members of the medical research project group, and the minimum qualifications are all doctors of medicine.

At this time, Chen Mo and Wu Bing were also in the laboratory, and Chen Mo had some documents in his hands.

"Now I will assign you your own tasks. The subject of our group is customized vaccine technology. This subject is a bit difficult. If you want to speed up the research and development, you must cooperate with me in the research."

When Chen Mo opened his mouth, several people cheered up.Although Chen Mo did not graduate from medical school, he has proved his strength in pharmaceutical research from the VFV virus to the success of the improved HX3 medicine, which is enough to be a mentor for any of them.

"You are divided into two groups of three or three. The first group, together with Academician Wu, is responsible for isolating the protective antigen gene of the virus and determining the gene sequence. The second group, together with me, builds a system platform for customizing vaccines. This is your project information. "

Chen Mo handed over the information in his hand to several people.

"This is an epoch-making technology. If it succeeds, it will have a revolutionary effect on the medical field. Medical scientists can quickly produce infectious disease vaccines for certain diseases, or even mixed vaccines carrying multiple antigens."

The six people were awe-inspiring, and their hearts were hot for a while.

The country is not a hard-hit area and is relatively calm.However, the international medical community is not peaceful. Almost all famous immunology doctors have been summoned to set up a special research team.

The improved HX3 medicament treats the symptoms but not the root cause.

The patient's condition is special, like severe schizophrenia, and it is also contagious. The countries in the hardest-hit areas are under unprecedented pressure.

Medical facilities and anti-epidemic supplies are already in urgent need.

Protective clothing, masks, and gloves are all disinfected and reused after use, and used repeatedly.The chances of some medical personnel being infected are rising. In some of the most serious countries, due to the extreme lack of medical facilities, patients have been detained in a quarantine area, which is controlled by military chemical defense forces.

Now using the HX3 drug, the patient regains consciousness and the management is relatively simple.But one month later, the backlog of patients has not been cured, the medicines have failed, and the medical facilities are insufficient. When the time comes, the patients lose their minds again, and no one knows what the consequences will be.

As time went by, there was no good news of breakthroughs in specific drugs in the medical community.Those who fight against the frontline of medical treatment began to cast a shadow over their hearts.Because the first batch of patients using the improved HX3 drug will soon face the consequences of drug failure.

Chapter 498 Disaster

Lindsay sat on the hospital bed, glanced at the opening of the window, and put away the newspaper in her hand.

He regained his consciousness with medication, and one hand was fixed on the hospital bed. In order to prevent him from getting sick, the hospital did not allow them to be free at all.

The hospital bed not far from him is the patient who was sent in shortly after he was sent to this isolation room.He was also infected with Redman virus, and used the improved HX3 drug to restore his mind.

This is the hardest-hit area in Belgium. There are two patients in one isolation room. Because there are too many patients, the isolation area here is already overcrowded. Before there is no specific medicine to treat it, I am afraid that this situation will continue for an unknown period of time.

"When did you say that the special medicine will come out?" Lindsay said, his voice was not tired, but also a little uneasy.This kind of waiting for death is not easy for anyone.

"I don't know." The patient opposite Lindsay shook his head, and his mental state was not very good.His name was Maud, and he had introduced himself to Lindsay before. The two were friends in need. In this closed isolation room, they chatted when they were bored, and they had already known each other.

"I don't know how long this medicine can last." Lindsay said.

"Hehe, it's almost time, I feel something is wrong now." Maud smiled wryly, but didn't speak.

Lindsay came back to his senses, his pupils shrank, and when he looked at Maud again, the other party was already shaking his head, as if he wanted to shake off the things in his head.

"Go away, go away!!"

"Ghost, ghost, don't come here."

"Go to hell."

Suddenly when Maud saw Lindsay, panic appeared on his face, he kept pulling his hands tied to the bed, retracted his body to the corner of the bed, and kept waving his other hand, as if seeing and its scary stuff.

Seeing this scene, Lindsay's pupils shrank, and fear floated in his heart.

This is the state after the onset, completely without self-awareness, like a mentally ill lunatic.I'm afraid that when I get sick, it won't be much better than this.

A feeling of despair welled up in his heart, making him completely flustered.

……

"The injection was successful, let him go."

In the Los Angeles quarantine area, Tiven pulled out the syringe in the patient's body, quickly retreated one meter away from the hospital bed, and stared at the patient who was struggling crazily on the bed.

Five minutes passed, and the patient on the hospital bed didn't show any intention of stopping. He still looked at him with crazy eyes, as if seeing an enemy.

This scene made the medical staff next to them heartbroken.

"Doctor Steven, why is the patient still not well?"

"The HX3 potion has failed." Tiven's voice was extremely heavy, and the haze in his heart became thicker.

"Then what should we do?" The voice of the medical staff was a little panicked.

"Fix him like this, don't let him go." Steven said: "The other isolation rooms should pay attention, and if the medicine fails, please notify me immediately."

"Okay." The medical staff hurriedly agreed.

After leaving the isolation room, Steven felt his heart was heavy, and he was a little flustered, but he had to force himself to remain calm.

The HX3 potion has failed.

The worst has come.

Once the medicine fails for the patient, it means that the first batch of users will become delirious again, and it will be a disaster for the whole world at that time.

And the catastrophe has come.

……

Tokai, Tokyo, New York, Ottawa, Paris, London, Berlin, Amsterdam...

Similar things are happening in every corner of the world.

The improved HX3 drug failed for the first batch of patients, and more and more patients, the virus in the body recovered, and the disease relapsed.In just one day, 227 people worldwide died due to disease recurrence.

The news plunged the world into unprecedented panic.

Seeing the relapsed patient, many infected people have collapsed mentality and despair, crying for doctor's treatment, but the response they get is only a sigh of regret.

Death, despair, fear, these are the themes of the quarantine area, all kinds of negative emotions, as if the hand of death is in their hearts, ready to take their lives away.

The first batch of medicines failed, and the one-month delay has passed.However, there is still no good news of drug breakthroughs in various medical groups around the world, which has caused many front-line medical staff to collapse.

……

"Dean, there are more and more out-of-control patients. There are not enough isolation rooms and beds, and there are not enough medical personnel. There are not enough masks, protective clothing, gloves, syringes, sedatives, ambulances, etc. Urgently needed medical equipment is already in short supply. , we need a lot of medical supplies, is there any new news from above?"

Luo Xie looked at the middle-aged and elderly people wearing glasses in front of him. He was Matt, the director of Victoria Hospital.Seeing that Matt didn't speak, Luo Xie was anxious and continued to ask.

"The HX3 medicine can only last for one month. Is there any new medicine at the research institute?"

"No." Matt shook his head with a sullen face: "There is no such thing in the whole world. According to the World Health Organization, research teams around the world have tried more than 4290 drugs, and all of them are ineffective against the virus. This virus is horribly overbearing."

"Then what should we do now? The hospital can no longer accommodate so many patients. There are still a steady stream of confirmed diagnoses. If this continues, once the critical point is exceeded, it will be completely finished. The medical staff in the entire hospital will be under the virus environment. The probability of infection And if the medical staff is infected, this vicious circle will open, and the entire hospital will become a dead building."

Luo Xie's voice was anxious.

Since the outbreak of the virus, many medical staff have been infected and died, which has put a lot of psychological pressure on the front-line medical staff.If there are other problems, I am afraid that this virus will really get out of control.

The air fell into a dead silence, except for Roger and Matt, everyone else felt heavy.

After a long time, Matt spoke slowly.

"Jointly ask the Center for Disease Control and Prevention to establish a centralized isolation area, which is convenient for management and does not need to be too scattered. Before there is no specific drug, single isolation of patients will have no effect, it will only increase manpower and workload."

The other doctors nodded in agreement.

As one of the hardest-hit areas in the UK, the number of sick people across the country has exceeded 5000. This does not include the number of people who have died and the number of patients who died of violence. There are more than 15 people in isolation. This is only the number in the UK. Some are even scarier.

The number of confirmed cases and deaths is setting a new high every day, which is already a very dangerous number.

If any isolation point goes out of control, it will really be a catastrophe.Centralized management of all patients is more convenient.At present, there is no specific medicine for treatment, even if it is isolated alone, it will not be of much use.In special circumstances, we can no longer take care of other issues, otherwise the epidemic will get out of control and it will be even more terrifying.

The UK Centers for Disease Control and Prevention announced the establishment of three centralized isolation areas to isolate and manage all confirmed patients.

The news shocked the medical world.

The epidemic has reached the point where it is about to get out of control. If this continues, no one can guarantee that this disaster will bring about a terrible ending.

Not long after the United Kingdom established a centralized isolation zone, other hardest-hit areas in Europe and the United States also announced the establishment of centralized isolation points in the hardest-hit areas, sending all confirmed patients to the isolation area, and centralized isolation and management by the military's chemical defense forces.

At this time, the number of confirmed cases worldwide has reached 7, and the death toll is refreshing every day. There are as many as 200 million quarantined people worldwide. Every time a patient is found, everyone who has come into contact with him will be quarantined.

Under various strict restrictive measures, the momentum of the crazy spread of Redman virus has begun to ease, but the death toll is also increasing.In the centralized isolation area, people die, despair, and collapse every day.Some patients who were still awake, some chose to commit suicide and died with dignity.

The news one after another makes everyone feel heavy. If there is no specific medicine, it means that all infected people will die, which will be a catastrophic number.

Chapter 499 Dawn of Victory

Hughes Medical Institute.

Headed by world-renowned immunologists such as Qiu Xiang and Judson, everyone is waiting for the medication situation in the isolation room.

Now that the Reedman virus epidemic is serious and the situation is special, the WHO and the Centers for Disease Control and Prevention of various countries have issued a notice that the medical team that studies the specific drug of Reedman can seek the consent of the family members of the awake patients and directly use it on the patients who have lost consciousness. Nontoxic and slightly toxic drugs tested.

This notification is very important. It saves them the process of testing new drugs on animals and can greatly shorten the drug development cycle.

Now all their medicines are administered directly to patients who have lost their minds.If they are not treated, they will definitely die, and if they are treated with new drugs, there is still a chance of recovery.

It was the 32nd attempt and all members were praying that it would pass.They were divided into eight groups and carried out drug exploration research from nine different directions. Until now, there is still not much progress.

Redman virus is too overbearing.

During the onset, except for mental hallucinations, all other body functions of the patient are much stronger than those of healthy people.After half a month, the patient will experience internal bleeding and eventually die.