Conscientious enterprises: all went bankrupt and donated money to the disaster area

Talking all over the place.

"Director Chen, his daughter has been cured, what about my father?"

"Director Chen, where is my lover? How is my lover?"

"Where is my husband? Director Chen, is my husband better? He is the pillar of our family. If he falls, our family will be over."

"..."

Chen Siyi immediately signaled everyone to be quiet, and explained: "Families, listen to me."

After the family members calmed down, Chen Siyi continued: "Luo Tongtong is the youngest and the lightest in this group of volunteers.

The time to culture CAR-T cells is the shortest.

So, her results came out the earliest.

The current examination results show that all cancer cells have been eliminated.

Your family members are still in the observation period, and the specific situation has to wait for the results of the inspection.

Please wait patiently for a few more days. "

"Director Chen, how many days are you waiting for?" A family member of the patient asked anxiously.

"Seeing other people come out, I can understand your worries." Chen Siyi replied: "However, you must also be clear that each individual is different.

The likelihood of adverse reactions varies.

These will affect whether they can leave the laboratory.

So, I can't give you an exact time.

However, please rest assured that my team and I will definitely do our best to heal. "

"Thank you Professor Chen!"

"Professor Chen has worked hard!"

"Everyone, don't embarrass Professor Chen, we have to think about it. You see, the daughter of the Luo family has recovered, and our relatives will definitely recover as well."

"That's right, the daughters of the Luo family have all come out, the possibility of our family members surviving must be higher."

Professor Chen did not respond to this.

Although, he knew that the results of the first inspection of the remaining nine people showed that the cancer cells had been eliminated.

He still didn't take the initiative to disclose.

As a doctor, the most taboo thing is to make some positive guarantees to family members.

Changes in the condition are sometimes out of human control.

Especially for CAR-T cell therapy, a new type of therapy, its side effects are still uncertain.

If there are too many guarantees, once something goes wrong, unnecessary medical disputes will occur.

During this period of time, Su Mu asked Gao Hai to send a test report every day.

He must know the content of the clinical trial as soon as possible.

At this time, he no longer cares about the wealth transformation system.

But has another peculiar mood.

Every time a clinical trial briefing is opened, it is like opening a blind box.

Seeing that the results of the experiment went well, he would smile knowingly.

He can't help but worry when he sees adverse reactions in patients.

Sometimes I really don't want to read the briefing, but I can't help but open it.

Always so nervous.

So far, clinical trials are going well.

However, there is also bad news.

Among the ten volunteers who participated in the experiment, three experienced adverse reactions.

It is mainly cytokine release syndrome, which basically occurs 2 to 3 days after the injection of CAR-T cells.

The good thing is that two patients with cytokine release syndrome were cured after a week of treatment.

In another patient, although the cytokine release syndrome was in remission, some body loss still occurred.

In this way, after 45 days of clinical trials, the first phase of clinical trials ended.

10 patients achieved a 100% cure rate, 30% had adverse reactions, and 10% of them had serious adverse reactions, causing certain physical damage.

Although, Xue Zhongnian and Gao Hai said, this result is already very good.

Out of ten people, only one was injured.

However, compared with the cured cancer, this damage is still insignificant.

At least, the patient's life has increased from less than half a year to at least five years, or even longer.

But Su Mu still felt a little uncomfortable.

He really hopes that patients treated with CAR-T cell therapy can fully recover.

Although, this hope is somewhat unrealistic.

The success of the first phase of the clinical trial caused an uproar in Long Country and even the world.

Dawu Hospital has received unprecedented attention.

Gao Hai, the little old man, sneaks out from his busy schedule.

While helping the biological laboratory of Dawu Hospital to deal with logistical problems, it did not relax the development of Dawu Health.

Then this wave of enthusiasm expanded wildly.

Not only has reached cooperation with many large pharmaceutical companies, but also some foreign pharmaceutical brands have actively approached Dawu Health for cooperation.

At the same time, the layout of the Dawu Health Examination Center has also begun.

The former Dawu Health, because of the financial constraints of the Dawu Biological Laboratory, could not develop with all its strength.

It is different now, the research and development of Dawu Biological Laboratory has basically been completed.

Funding requirements are greatly reduced.

The vacated part of the funds, taking advantage of the success of the research and development of Dawu Biolabs, happened to be used by Dawu Health for expansion.

The speed of development is no different from riding a rocket.

Chapter 178 The Desperate Cost

With the rapid development of Dawu Health, the second phase of clinical practice in Dawu Hospital is also on the right track.

The number of participants in the second phase has increased compared with the first phase.

From ten people in the first phase to 100 people.

Because of the increase in the number of people, Dawu Hospital temporarily allocated a building and transformed it into a sterile ward.

This barely meets the needs of patients.

At the same time, due to the increase in the number of patients, the staff of Chen Siyi's team has begun to be stretched.

The professionalism of CAR-T cell therapy is relatively strong, and a group of corresponding doctors from Dawu Hospital has been added.

But there is still no way to meet the needs of phase II clinical trials.

The general practice is to extend the time of phase II clinical trials.

Doing it several times can effectively relieve the pressure on doctors.

But the situation is different now, and most of these patients are numbered.

The longer the delay, the higher the danger to life.

Therefore, after Su Mu personally discussed with Zhang Mingyuan, the director of the Department of Health, he decided to temporarily recruit a group of doctors from Kyoto Concord Hospital, Kyoto No. 1 People's Hospital and other hospitals to participate in the experiment.

Hospitals such as Kyoto Concord have shown great interest in such matters.

The most powerful doctors have been sent to help.

Of course, by the way, learn related technologies, and later, you can set up your own CAR-T cell therapy related team.

In this regard, Su Mu naturally chose to acquiesce.

You must know that cancer has a huge patient group in Longguo, and Dawu Hospital alone can only play a very limited role.

It is necessary for the medical workers of the Longguo system to work together to study and master relevant technologies.

In order to better serve the Dragon Kingdom society.

These people entering the laboratory in advance can shorten their study time later, and after leaving the biological laboratory of Dawu Hospital, they can serve patients as soon as possible.

While they were busy with the second phase of the experiment, Su Mu asked Gao Hai to start preparing for the third phase of the experiment.

Su Mu's goal is to increase the number of patients in the Phase III trial to 500.

For 500 people, at least [-] sterile wards are needed.

Fortunately, Dawu Hospital was built in the direction of the largest private hospital.

At the beginning of its establishment, there were more than 3000 beds.

There are also a large number of vacant buildings.

This makes the modification a little easier now.

Everything is developing steadily.

Time soon came to July.

The third phase of the experiment is over.

The summary of the experimental results has appeared on Su Mu's desk.

Downstairs is the carnival of the patient's family members.

During this period of time, many family members of patients have expressed their gratitude to Dawu Hospital.

Seeing their laughter from the bottom of his heart, Su Mu felt an indescribable sense of accomplishment.

After all, he was the one who firmly supported Chen Siyi when everyone opposed CAR-T cell therapy.

This is where CAR-T cell therapy is today.

Even though, the original intention of investing in CAR-T cell therapy is not so noble.

But before the result, everything is secondary.

Open the "Summary of Experimental Report on Phase III CAR-T Cell Therapy at Dawu Hospital" that Chen Siyi compiled overnight.

After the hard work of Chen Siyi's team.

Of the 12 patients in the Phase III clinical trial, only [-]% experienced adverse reactions.

10% of them experienced mild adverse reactions and returned to normal life after short-term treatment.

The remaining 2% had serious adverse reactions, but after long-term treatment, they all got better.

The results of such clinical trials are already considered good.

After the third phase of the clinical trial, Zhang Mingyuan brought relevant experts from the Department of Health and academicians from the School of Biology of the Long National Academy of Sciences to conduct relevant reviews.

These expert teams and academicians carefully reviewed the patient cases of the Phase III clinical trials of Dawu Hospital.

At the same time, patients who have been discharged from the hospital were also investigated.

Luo Tongtong, who was hospitalized for the first term, has already returned to his hometown with his father.

It should have been almost half a year since she was cured and discharged from the hospital.

In the past six months, she has returned to school classes, and her life has completely returned to normal.

The expert team took Luo Tongtong for another half-year inspection.

No cancer cells were found, and the patient recovered well after the illness.