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Chapter 153 Looking for medicine materials, glucose (1)

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In the same year, four French scientists, Louis Jacquesthénard, Joseph Louis Gaylussac, Jean-Baptiste Biot and Jean-Baptiste André Dumas, jointly published an article on the post- A review of Mr. Perigo's collection of academic papers entitled Studies into Nature and the Chemistry of Sugars

French "rapportsurunmémoiredem.péligiot,intitulé:recherchessurlanatureetlespropriétéschimiquesdessucres".

On page 109 it reads: “Those substances derived from grapes, starch, honey and even those that cause diabetes have the same composition and properties, naming this single substance glucose.

"Ilrésultés paraisons faites parm.péligot, quelesucrederaisin, celuidamidon, celuidediabètesetceluidemielontparfaitementlamêmepositionetlesmêmespropriétés, et constituentunseulcorpsquenousproposonsdappelerglucose1.1γλeuxo,mot,vindoux."

Due to the important position of glucose in living organisms, understanding its chemical composition and structure became an important topic in organic chemistry in the 19th century.

In 1884, Emil Fischer began studying sugars.

There were only four kinds of monosaccharides known at that time: two kinds of aldohexose glucose, galactose, two kinds of ketohexose sugar, and sorbose. They have the same molecular formula c4h6o12. Giannini, a chemist at the University of Munich, initially discovered that glucose Galactose and galactose are linear five-hydroxy aldehydes, and fructose and sorbose are linear five-hydroxy ketones.

Fisher discovered that glucose, fructose, and mannose formed the same vein as benzene, and therefore concluded that these three sugars had the same configuration below the second carbon atom.

Based on the stereoisomerism theory of vanthoff and elebl, Fisher deduced that aldohexose has 16 possible configurations.

Using oxidation, reduction, degradation, addition and other methods, by 1891, he determined the configurations of all members of the d series of aldohexoses.

In 1892, the German chemist Fischer determined the chain structure of glucose and its stereoisomers, and won the 1902 Nobel Prize in Chemistry for his great achievements in stereochemistry.

Physical properties of glucose:

Glucose is colorless crystal or white crystalline or granular powder, odorless, sweet, hygroscopic, and easily soluble in water.

1 Optical activity

The specific optical rotation value of ad glucose under light at 20 degrees Celsius is 52.2.

2Solubility

The maximum concentration of a single glucose solution is 20 at 50 degrees Celsius.

3 sweetness

The specific sweetness of ad glucose is 0.7.

4 viscosity

The viscosity of glucose increases with increasing temperature.

Density: 1.544gcm3.

Melting point: 153158c.

Boiling point: 410.797cat760mmhg.

Chapter 154 Preview: Looking for Glucose 2

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