Rebirth of the God-level Xueba

Anyone who came over to lobby Yang Rui at random, Yang Rui was ready to go back directly.

If it doesn't help, you can also turn on the "I don't listen, I don't listen, I just don't listen" mode.

However, Yang Rui couldn't even listen to what Professor Cai said.

Cao Baoming and Wang Guohua, who would follow him, were left behind, and they were walking around in the laboratory. Yang Rui invited Professor Cai into the office.

Professor Cai did not conceal his purpose. He sat down and first mentioned the Jingxi Pharmaceutical General Factory. Then, he talked about the investment of the Jingxi Pharmaceutical General Factory in biological experiments over the years. Then, the conversation changed. "The Jingxi General Pharmaceutical Factory will not be able to sustain it anymore. They used to produce tablets and powders. Now the southern factories are opening one after another. The price is lower than their cost. Customers were rushed over. Qin Hanchi’s agent for Miki’s medicine was the last fight. If it fails, the thousands of workers at the Jingxi Pharmaceutical General Factory and the raw material factory for them will be in trouble. ."

"Do you know Qin Hanchi?" Yang Rui asked.

"I have seen it, but this time it was Lao Zhang who entrusted me to my place." Professor Cai went on to explain: "Lao Zhang belongs to the GMP Preparatory Committee. He also supported the by-election before. In addition, several old friends from the Ministry of Health , Also called."

When Yang Rui ran projects and results appraisal with Professor Cai before, he saw that Professor Cai has a vast network, but from the other side, a broad network also means that he has to bear the cost of making friends.

Yang Rui nodded silently and continued to listen.

Professor Cai saw this and said, "If you have any thoughts, just tell me. If you can tell, I will tell them. If you can't, let's discuss it together."

Then, Professor Cai smiled and said, "Although I'm here to help Qin Hanchi speak, I can also help you speak."

Yang Rui smiled bitterly: "Why everyone thinks I have ulterior motives."

"Yep?"

"I didn't trust the drug, so I asked them to supplement the safety test." Yang Rui reluctantly said: "The publicly published research report of the law is very inadequate. It is very risky to rashly produce and promote it in China. Big."

"Risier than proprietary Chinese medicine?"

Yang Rui was speechless. In this discussion, he and Professor Cai are not of the same order of magnitude.

After thinking about it for a moment, Yang Rui said: "The scale of use of Lubboding is larger than that of proprietary Chinese medicines. In addition, the design of Lubbing is designed for long-term medication. Therefore, if there are safety issues, its risks will continue to accumulate. , I think it’s not wrong to be more rigorous."

Professor Cai looked at Yang Rui for a while, and suddenly said, "This doesn't look like your style."

"What is my style?" Yang Rui was dumbfounded.

"Go ahead." Professor Cai gave his own answer.

Yang Rui recalled that when he was working on potassium ion channels, he was indeed advancing. What PCR did was relatively simple, but the subsequent lawsuits amounted to millions of dollars. He also didn't want any reconciliation. He tried to fight forever, and the subtext of "one forever" is not a huge risk.

Yang Rui was quite embarrassed. Thinking about it this way, he did have some "one moment and another moment" questions.

"Everyone is talking about me now. Isn't my reputation unpleasant?" Yang Rui brushed his face a lot, and he could guess how the people think of him.

When "this time, another time" is linked to power, there is never any good talk.

Professor Cai nodded and said, "The scale of the Jingxi Pharmaceutical General Factory ranks first in the country. Qin Hanchi has been the director of the factory for nearly ten years, and he is not a bad person."

Yang Rui sighed and said, "I don't want to be a bad person either."

"Then let Jingxi Pharmaceutical General Factory pass the customs."

"Liu Bo must have a problem." Yang Rui stopped talking around and answered straightforwardly.

Professor Cai naturally asked a question that Yang Rui did not want to answer further: "What is the problem?"

Yang Rui could not answer.

As a kind of anti-arrhythmic drug, the foundation of its academic research is actually very solid. Identify premature beats as a disease, and then associate premature beats with more serious heart diseases, and then determine that inhibiting premature beats is beneficial to reduce the risk of heart disease—this entire academic chain is not a day or two, nor is it a person Two people make it. This is an academic research that has been established by hundreds of scholars over a decade ago, and Lübolding is just one of the star products.

Antiarrhythmic drugs are more than just one drug. In the 1980s, almost all major pharmaceutical companies were involved.

In the past ten years or so, in the process of the development of many drugs, hasn't anyone questioned the entire academic chain?

Of course there is.

However, academic discussions are only academic discussions after all. The most important problem is that anti-arrhythmic theory has no fundamental flaws.

Even Yang Rui could not say categorically that the anti-arrhythmic theory is wrong.

The anti-arrhythmic theory may not be wrong. In the simplest way of thinking, if the heart does not beat prematurely, it is better than premature heart beats. After all, premature heart beats are always an abnormal physiological phenomenon, and if they can be treated or suppressed at no cost, it seems to be a good thing.

Therefore, the key to the problem is back to the safety of Liberdine itself, or the safety of such drugs itself.

So, how to prove the safety of Lübolding?

Yang Rui knows that the problem with anti-arrhythmic drugs like Libertine lies in their impact on electrical pulses.

But there is no proof. The Miki company made a file cabinet file to prove its safety and efficacy tests.

For Yang Rui, the best way to prove it is through clinical trials, because the side effects of Liberdine are hidden and take a long time to manifest. Therefore, ordinary clinical trials with a small scale and short duration are not enough. You need to find hundreds of them. Even thousands of patients with arrhythmia undergo a double-blind test. Half of them take Liberdine and half take a placebo, which is equivalent to a large-scale clinical phase one.

Regarding Yang Rui’s experience in removing iron ketones, to get a more definite answer, it would cost about 40 million U.S. dollars, and it would be almost the same in half a year. Of course, the number of patients with possible heart damage must be somewhat. Say no more people will die.

Did Yang Rui get 40 million US dollars? Of course, I can't get it. I haven't seen much of the milestone payment for iron ketone. Besides, I can't do it like this. He has 40 million US dollars and can study a new drug.

And if you don't do clinical trials and engage in academic debates, Yang Rui's current status and status will be the first, and he won't be able to beat others.

There are also great talents in the research team that do the law and determination. They have been working on this medicine for nearly ten years, and they have memorized more information than Yang Rui has read. Even if Yang Rui can speak eloquently, it will not add to the ability of others to pass the FDA. .

To be reasonable, the FDA has always been criticized for being too inefficient and too demanding, but there are very few cases where the review is not strict.

There may be incomplete areas in the review of Lüberding, but in terms of the concealment and slowness of its side effects, the FDA has actually done well enough.

The FDA may have asked all the questions Yang Rui could verbally ask.

"The key now is not that I have to prove the problem of Luboding, but that the Jingxi Pharmaceutical General Factory has to prove to me that Luboding is okay." Yang Rui's eyebrows drooped, then raised quickly, and said: "Professor Cai, I'm sorry, I have to save your face, and I have to be responsible for my signature."

"Even if the Jingxi Pharmaceutical General Factory finds more people to put pressure on, you will not let it go, will you?" Professor Cai asked calmly.

Yang Rui nodded slightly.

"You know, Qin Hanchi didn't just find me. In order to pass the law, the whole Jingxi Pharmaceutical Factory is thinking of ways. And..." Professor Cai lowered his voice and said, "Their reason is also Very abundant."

"I know."

"Aren't you afraid?"

"I'm afraid, I'm afraid to die." Yang Rui smiled bitterly. If he was not afraid, how could he call both Wang Guohua and Cao Baoming over.

Even without violence, Yang Rui is actually not sure how long he can carry it. As the saying goes, when you arrive in Bei@京城, you know the official small, and the taxi drivers of Bei@京, who are all around, can know a cadre at the department and department level. Qin Hanchi himself is at the department and department level, and what level can he contact? cadre?

Yang Rui did not live in a vacuum when the officials crushed people to death.

But ~www.wuxiaspot.com~ Yang Rui asked himself, he may not be able to completely prevent Lü Bo Ding, but it would be good to delay it by one day. Libo Ding will enter China one day later, and the number of people affected by it may be tens of thousands, and there may be some people who will survive because of this, and there will definitely be many people, so it is free from the risk of heart damage. , And thus live a few more years, maybe even more than ten years.

Furthermore, the delay of the Jingxi Pharmaceutical General Factory’s commissioning of production may also reduce the supply of Liberdine in the global market. The supply of pharmaceutical factories has decreased, and pharmaceutical representatives will not be so hard to promote it. The number of patients in Boding might be reduced, and there will be fewer deaths. In any case, Americans are also human. It is too sad to die on a carefully developed drug in vain.

Professor Cai looked at Yang Rui's expression, but he realized Yang Rui's state of mind inexplicably, just like the one he saw Yang Rui in Tang Ji's laboratory.

"This is still your style." Professor Cai sighed.

Yang Rui looked at him.

"Your style." Professor Cai pointed at him with his finger, and said: "It's never going forward."

...