Ji Luo looked at Gong Qiyan uncertainly.
... He has also been rotated in the hospital, knowing that the family members are called to talk alone, and they may face some not-so-optimistic situations.
But Gong Qiyan's expression was normal, and even Ji Luo couldn't see any flaws in his expression.
... This made Ji Luo panic.
All the way in silence, the two came to Gong Qiyan's office.
Warm warm light, the floor-to-ceiling windows are dotted with the orange lights of the city that is about to enter the night.
The lights in many skyscrapers have already been turned on, and the shadows of people are vague. Everything shows the infinite vitality of the city.
Ji Luo wanted to ask Gong Qiyan what he asked him to do.
But the bottom of the throat is sour, unable to speak.
Such a road is very simple to walk, but in fact, in Ji Luo's heart, he has practiced many, many pessimistic situations several times.
Until the two stood facing each other across a desk, Ji Luo couldn't say a word.
What the hell do you mean...
If it's a good situation, why not just say it in the ward?
Why did you call me out alone to talk?
It was Gong Qiyan who looked at him for a while, then spoke in a deep voice.
"Ji Luo, how much do you know about lung cancer?"
Ji Luo raised his eyes, his eyes moving slightly.
Thinking of the medical foundation of the previous life, and the severe wheezing sound coming from the man's chest, and the smell of blood in the middle of the night, Ji Luo thought for a while and said, "I know something."
He actually 'probably' read some books on lung diseases later on.
The so-called "roughly" means that I didn't learn it especially for Ji Ling, but... the extremely efficient and focused Master Ji, when he is at home with nothing to do, puts the basic medical knowledge about lung diseases and special disease research, and then Plus a lot of cutting-edge Lancet articles, just look at them 'casually'.
Gong Qiyan nodded, turned on the computer at hand, tapped with his fingertips, and brought up various immunohistochemical reports about Ji Ling.
The molecular staining map of the sliced tissue is displayed on the screen.
It is so densely packed that it is difficult to identify, and there are obscure pathological analysis underneath, as well as many parameters and expression formulas of yin and yang values.
Gong Qiyan pointed to a line of words: "Do you understand what I read here? About the classification of lung cancer. Generally, there are four types: adenocarcinoma, squamous cell carcinoma, large cell lung cancer and small cell lung cancer."
Ji Luo glanced and saw the value belonging to Ji Ling.
After a while, his complexion suddenly relaxed.
Ji Luo: "Well, I know. What you show here is...5q33 loss of heterozygosity, cmyc amplification, tp53 mutation, lec, sclc, ki67...meaning, non-small?"
"Yes." A trace of surprise flashed across Gong Qiyan's pupils, but he quickly returned to normal. He seemed not surprised by Master Ji's medical level, "You can understand, then you can understand what I'm going to say next. It should be easy to understand."
Ji Luo focused his eyes on the report card.
"Non-small cell lung cancer accounts for the vast majority of lung cancer patients." Gong Qi spoke slowly, as if he was thinking about something, "Compared with small cell lung cancer, it is easier to treat with the current medical level."
"Yes."
Ji Luo raised his eyelids and thought of the data he had seen before.
Small cells are more likely to metastasize and relapse, are difficult to resolve, and have an extremely low five-year survival rate.
Gong Qiyan: "...But non-small cell does not mean good treatment. For advanced patients, the five-year survival rate is only more than ten percent."
It means that only a dozen percent of patients can survive for five years.
"...Well." Ji Luo's fingertips slid a little distance on his desk.
If it is based on this data, then the brother before wearing the book is very likely...
Ji Luo didn't dare to think about it, so he closed his eyes a little.
Gong Qiyan looked at Ji Luo, and continued: "...Ji Ling's part is a very early expression. According to the standard treatment plan, we expect the treatment to end after four rounds of chemotherapy. Ji Luo, you should relax first, Sit down and talk."
The clenched heart slowly relaxed a little.
Ji Luo didn't realize that he was so tense that he didn't even pay attention to his breathing, he was tense all the time, and now his head was a little dizzy due to lack of oxygen.
He took a step back, exhaled and exhaled several times, and finally sat down in the swivel chair.
Hearing Gong Qiyan say these words, Ji Luo felt much better.
Those pessimistic fantasies when I came here just now, such as 'How to pay for the death price of going through the book twice' and 'Is there no cure for early detection' and more serious thoughts gradually dissipated.
Ji Luo calmed down and asked Gong Qiyan: "Okay, um...then, since this is the case, why did you call me out alone? Just say no together in the ward? What is the chemotherapy plan? When will it start? "
Gong Qiyan tapped his finger on the screen, scrolled to another report card, looked at it for a while and didn't speak, as if he was considering his words.
Ji Luo looked over with his fingertips, and saw that this document was "Guidelines for Chemotherapy Medications"
It contained the chemotherapy plan prescribed by the oncology department for Ji Ling's illness.
Gong Qiyan tilted his head, thought for a long time, and said slowly: "Yes. But..."
Ji Luo: "..."
The heart seemed to be tightly squeezed by a hand again, and the breathing was restrained again.
but?
but what?
"Standard chemotherapy uses platinum-based drugs. For Ji Ling, there seems to be no problem. However, in many years of clinical practice, we found that his immunohistochemistry suggested that the disease category will be quite low. Resistance occurs."
The amber pupils in the peach blossom eyes trembled.
Not low drug resistance!
"You mean... the possibility of recurrence is high?"
Hearing the trembling voice of the young man in front of him, Gong Qiyan sighed and nodded silently.
Then the finger swipe the screen again to come to the third page of the report.
Gong Qiyan: "Look at this, other indicators are OK, and platinum drugs will play a role. But the question is whether there will be drug resistance in the later stage. If drug resistance occurs, the prognosis is not very good, because there is no other chemotherapy. The plan can keep up."
Ji Luo: "..."
Gong Qiyan: "Of course, high drug resistance does not mean that drug resistance will definitely occur."
There are no 100% certain events in medicine.
Ji Luo: "...Is that all? Then he will definitely not develop drug resistance, just... don't think about this for now..."
"and also."
Ji Luo: "?!"
Gong Qiyan looked at Ji Luo's ugly face, and it seemed difficult to say what to say next.
But there is no way.
As a doctor, I heard that such things happened in the family of family members, and I can understand their sadness, but... there is no good way.
Gong Qiyan clicked on another document.
"The problem of drug resistance is just one of them. The point is that Ji Ling's non-small pressure type indicates met amplification. As for met amplification, until now, the academic community has no good solution."
Ji Luo looked at Gong Qiyan in shock.
what happened.
What is Gong Qiyan talking about?
Why is it a very simple conversation, but now I suddenly can't understand it!
He felt his head buzzing, and his ears were filled with sharp noises.
"There is no good solution...?"
Ji Luo murmured.
Gong Qiyan nodded slightly, and answered Ji Luo patiently: "Met amplification will cause the activation of a cancer cell signaling pathway. The activation of the signaling pathway means that this type of cell will proliferate more easily."
Ji Luo's hands clenched into fists!
"What are you kidding! He, he only smoked for a short time, how come, how come!"
"..." Gong Qiyan frowned, "The source of cancer is not necessarily caused by smoking."
Ji Luo's brain was running fast, trying to digest these few paragraphs of Gong Qiyan's words.
But... so difficult.
Met amplification?
Non-small?
Platinum drugs?
why!
His breathing gradually became short of breath, the corners of his eyes were stained with a lot of blush, and his whole body began to tremble continuously. Would a person who had just gained everything soon face the helplessness of losing everything again? !
I do not accept--
Still thinking about what Ji Ling said just now.
'Luoluo, I love you so much and want to be with you forever. '
... so suffocating.
There was an uncontrollable growl in his chest, Ji Luo propped his hands on the table, and raised his head suddenly!
"Did I do something wrong! Do another immunohistochemistry!!!"
Gong Qiyan gently agreed: "Yes."
"There must be something wrong, how could it be like this! How could it be... like this..."
"..." Gong Qiyan quickly issued an instruction to recheck in the system.
But Gong Ci's medical treatment is very advanced.
In fact, before arranging the inspection, he has repeatedly emphasized that this report should be given great attention, so the probability of making mistakes is extremely small.
Even so, he still comforted Ji Luo, "Don't worry..."
"How could I not be in a hurry!" Ji Luo couldn't bear it, and raised his volume again.
Facing anyone, he can control himself well.
Only about lovers.
He, he can't...
"Met? Met amplification? Non-small? Platinum?"
With these words in his mouth, Ji Luo recalled his knowledge about lung cancer at super high speed!
But under extreme pressure and anxiety, only the word 'price' was played back and forth in my mind.
So the price of wearing a book...
The 'no small price' my brother paid was two unavoidable deaths, right? !
Ji Luo suddenly felt so desperate.
A glimmer of life is in sight, and the future where the two can be together for a long time is close at hand.
What nonsense, met——
Seeing Ji Luo's eyes turn red, Gong Qiyan put down the things in his hand, walked up to him and patted his shoulder to help him regain his senses and relax, "Although there is no good treatment method now , but maybe in the future? Let’s start with standard chemotherapy first, he’s young and in good health, so it doesn’t necessarily mean…”
Ji Luo couldn't listen.
It's all fucking futile consolation.
It will take at least several years to come up with a new diagnosis and treatment plan!Maybe in the future?The research and development of a new drug means research and development!
Ji Luo almost wanted to bite his lips to bleed, he tried his best to restrain his body from trembling, trying to calm down, but tossing and turning, only a few large words met were amplified in his mind.
Wait, met?
"Say it again? Met expansion?" Ji Luo's memory revolving door suddenly flashed, thinking of the articles he had written before he came here.
There is also Ji Ling's report in front of him.
[met14 exon]
- I remembered.
"Gong Qiyan! Fei Xiaomet has a mutation, what kind of platinum drug do you use!" Ji Luo raised his voice and slammed the table.
Gong Qiyan looked at Ji Luo in surprise.
With a trembling voice, Ji Luo's academic articles appeared in front of his eyes.
It was an article he read when he was bored not long ago.
"The new met treatment program for non-small lung cancer has passed the third phase of clinical trials!"Nearly one million patients are expected to benefit globally》…
What is written in it?
"Traditional chemotherapy with docetaxel, plus met inhibitor targeted therapy, Gong Qiyan!" Ji Luo grabbed Gong Qiyan's shoulder and shook wildly, "Who are you scaring at night, I was almost scared to death by you—— "
Gong Qiyan did not expect Ji Luo to say such a sentence, he was a little embarrassed: "You said... docetaxel plus met inhibitors? Ji Luo, although some people in the academic circles have suggested that docetaxel is good for Fei Xiao, but now It has not been clinically tested..."
Ji Luo was taken aback for a moment, and then understood.
This should be a small difference between the two worlds.
But it's okay.
This young master is here to hang up!
Ji Luo categorically said: "Do as I say."
Gong Qiyan stared at Ji Luo for a while, and said: "Although this behavior is not in compliance with the rules, but based on our friendship, and this is a matter of your own family, I can of course submit an application material for you. But Ji Luo , are you sure? Docetaxel? ... And, the met inhibitor you mentioned, what is that? I have never heard of it."
Ji Luo: "?"
He immediately rushed to the computer and searched for met inhibitors on professional websites.
impossible!
Why not!
I have seen it in my previous life, all of which have passed the third phase of clinical trials and are available to the public, but you don’t have any here!
——Not really.
An empty browser, prompting him 'there is no search result for this keyword'!
The conference room fell silent again.
……
Ji Luo sneered in his heart.
It's up to people to plan things.
What is the price of wearing a book.
The price means that there is a chance to survive, but the actual conditions are not satisfied?
Don't talk nonsense with Master Ben.
I know what to do, but can I be stopped by some vain price?
……
Master Ji relaxed his fingers and sat in the swivel chair.
Cross your legs and cross your hands over your knees.
Ji Luo is now extremely sober.
All the articles and knowledge learned, at this moment, all clearly appeared in front of my eyes.
He raised his chin slightly, calm and arrogant.
It seems to be back to the moment when he concentrated on working overnight and teamed up with Ji Ling to kill the business world.
Only this time, the battlefield has changed.
How much suffering has been experienced.
With my brother waiting for me, I am not afraid of anything.
"If this is an ordinary person, I really can't do anything about it, but I'm different—hey, let me use your Gong Ci's laboratory and scientific research team." Ji Luo hooked his lips, "Isn't it just an inhibitor? Small meaning. For Thank you for performing the operation on him, and I will send you a scientific research problem to solve."
... He has also been rotated in the hospital, knowing that the family members are called to talk alone, and they may face some not-so-optimistic situations.
But Gong Qiyan's expression was normal, and even Ji Luo couldn't see any flaws in his expression.
... This made Ji Luo panic.
All the way in silence, the two came to Gong Qiyan's office.
Warm warm light, the floor-to-ceiling windows are dotted with the orange lights of the city that is about to enter the night.
The lights in many skyscrapers have already been turned on, and the shadows of people are vague. Everything shows the infinite vitality of the city.
Ji Luo wanted to ask Gong Qiyan what he asked him to do.
But the bottom of the throat is sour, unable to speak.
Such a road is very simple to walk, but in fact, in Ji Luo's heart, he has practiced many, many pessimistic situations several times.
Until the two stood facing each other across a desk, Ji Luo couldn't say a word.
What the hell do you mean...
If it's a good situation, why not just say it in the ward?
Why did you call me out alone to talk?
It was Gong Qiyan who looked at him for a while, then spoke in a deep voice.
"Ji Luo, how much do you know about lung cancer?"
Ji Luo raised his eyes, his eyes moving slightly.
Thinking of the medical foundation of the previous life, and the severe wheezing sound coming from the man's chest, and the smell of blood in the middle of the night, Ji Luo thought for a while and said, "I know something."
He actually 'probably' read some books on lung diseases later on.
The so-called "roughly" means that I didn't learn it especially for Ji Ling, but... the extremely efficient and focused Master Ji, when he is at home with nothing to do, puts the basic medical knowledge about lung diseases and special disease research, and then Plus a lot of cutting-edge Lancet articles, just look at them 'casually'.
Gong Qiyan nodded, turned on the computer at hand, tapped with his fingertips, and brought up various immunohistochemical reports about Ji Ling.
The molecular staining map of the sliced tissue is displayed on the screen.
It is so densely packed that it is difficult to identify, and there are obscure pathological analysis underneath, as well as many parameters and expression formulas of yin and yang values.
Gong Qiyan pointed to a line of words: "Do you understand what I read here? About the classification of lung cancer. Generally, there are four types: adenocarcinoma, squamous cell carcinoma, large cell lung cancer and small cell lung cancer."
Ji Luo glanced and saw the value belonging to Ji Ling.
After a while, his complexion suddenly relaxed.
Ji Luo: "Well, I know. What you show here is...5q33 loss of heterozygosity, cmyc amplification, tp53 mutation, lec, sclc, ki67...meaning, non-small?"
"Yes." A trace of surprise flashed across Gong Qiyan's pupils, but he quickly returned to normal. He seemed not surprised by Master Ji's medical level, "You can understand, then you can understand what I'm going to say next. It should be easy to understand."
Ji Luo focused his eyes on the report card.
"Non-small cell lung cancer accounts for the vast majority of lung cancer patients." Gong Qi spoke slowly, as if he was thinking about something, "Compared with small cell lung cancer, it is easier to treat with the current medical level."
"Yes."
Ji Luo raised his eyelids and thought of the data he had seen before.
Small cells are more likely to metastasize and relapse, are difficult to resolve, and have an extremely low five-year survival rate.
Gong Qiyan: "...But non-small cell does not mean good treatment. For advanced patients, the five-year survival rate is only more than ten percent."
It means that only a dozen percent of patients can survive for five years.
"...Well." Ji Luo's fingertips slid a little distance on his desk.
If it is based on this data, then the brother before wearing the book is very likely...
Ji Luo didn't dare to think about it, so he closed his eyes a little.
Gong Qiyan looked at Ji Luo, and continued: "...Ji Ling's part is a very early expression. According to the standard treatment plan, we expect the treatment to end after four rounds of chemotherapy. Ji Luo, you should relax first, Sit down and talk."
The clenched heart slowly relaxed a little.
Ji Luo didn't realize that he was so tense that he didn't even pay attention to his breathing, he was tense all the time, and now his head was a little dizzy due to lack of oxygen.
He took a step back, exhaled and exhaled several times, and finally sat down in the swivel chair.
Hearing Gong Qiyan say these words, Ji Luo felt much better.
Those pessimistic fantasies when I came here just now, such as 'How to pay for the death price of going through the book twice' and 'Is there no cure for early detection' and more serious thoughts gradually dissipated.
Ji Luo calmed down and asked Gong Qiyan: "Okay, um...then, since this is the case, why did you call me out alone? Just say no together in the ward? What is the chemotherapy plan? When will it start? "
Gong Qiyan tapped his finger on the screen, scrolled to another report card, looked at it for a while and didn't speak, as if he was considering his words.
Ji Luo looked over with his fingertips, and saw that this document was "Guidelines for Chemotherapy Medications"
It contained the chemotherapy plan prescribed by the oncology department for Ji Ling's illness.
Gong Qiyan tilted his head, thought for a long time, and said slowly: "Yes. But..."
Ji Luo: "..."
The heart seemed to be tightly squeezed by a hand again, and the breathing was restrained again.
but?
but what?
"Standard chemotherapy uses platinum-based drugs. For Ji Ling, there seems to be no problem. However, in many years of clinical practice, we found that his immunohistochemistry suggested that the disease category will be quite low. Resistance occurs."
The amber pupils in the peach blossom eyes trembled.
Not low drug resistance!
"You mean... the possibility of recurrence is high?"
Hearing the trembling voice of the young man in front of him, Gong Qiyan sighed and nodded silently.
Then the finger swipe the screen again to come to the third page of the report.
Gong Qiyan: "Look at this, other indicators are OK, and platinum drugs will play a role. But the question is whether there will be drug resistance in the later stage. If drug resistance occurs, the prognosis is not very good, because there is no other chemotherapy. The plan can keep up."
Ji Luo: "..."
Gong Qiyan: "Of course, high drug resistance does not mean that drug resistance will definitely occur."
There are no 100% certain events in medicine.
Ji Luo: "...Is that all? Then he will definitely not develop drug resistance, just... don't think about this for now..."
"and also."
Ji Luo: "?!"
Gong Qiyan looked at Ji Luo's ugly face, and it seemed difficult to say what to say next.
But there is no way.
As a doctor, I heard that such things happened in the family of family members, and I can understand their sadness, but... there is no good way.
Gong Qiyan clicked on another document.
"The problem of drug resistance is just one of them. The point is that Ji Ling's non-small pressure type indicates met amplification. As for met amplification, until now, the academic community has no good solution."
Ji Luo looked at Gong Qiyan in shock.
what happened.
What is Gong Qiyan talking about?
Why is it a very simple conversation, but now I suddenly can't understand it!
He felt his head buzzing, and his ears were filled with sharp noises.
"There is no good solution...?"
Ji Luo murmured.
Gong Qiyan nodded slightly, and answered Ji Luo patiently: "Met amplification will cause the activation of a cancer cell signaling pathway. The activation of the signaling pathway means that this type of cell will proliferate more easily."
Ji Luo's hands clenched into fists!
"What are you kidding! He, he only smoked for a short time, how come, how come!"
"..." Gong Qiyan frowned, "The source of cancer is not necessarily caused by smoking."
Ji Luo's brain was running fast, trying to digest these few paragraphs of Gong Qiyan's words.
But... so difficult.
Met amplification?
Non-small?
Platinum drugs?
why!
His breathing gradually became short of breath, the corners of his eyes were stained with a lot of blush, and his whole body began to tremble continuously. Would a person who had just gained everything soon face the helplessness of losing everything again? !
I do not accept--
Still thinking about what Ji Ling said just now.
'Luoluo, I love you so much and want to be with you forever. '
... so suffocating.
There was an uncontrollable growl in his chest, Ji Luo propped his hands on the table, and raised his head suddenly!
"Did I do something wrong! Do another immunohistochemistry!!!"
Gong Qiyan gently agreed: "Yes."
"There must be something wrong, how could it be like this! How could it be... like this..."
"..." Gong Qiyan quickly issued an instruction to recheck in the system.
But Gong Ci's medical treatment is very advanced.
In fact, before arranging the inspection, he has repeatedly emphasized that this report should be given great attention, so the probability of making mistakes is extremely small.
Even so, he still comforted Ji Luo, "Don't worry..."
"How could I not be in a hurry!" Ji Luo couldn't bear it, and raised his volume again.
Facing anyone, he can control himself well.
Only about lovers.
He, he can't...
"Met? Met amplification? Non-small? Platinum?"
With these words in his mouth, Ji Luo recalled his knowledge about lung cancer at super high speed!
But under extreme pressure and anxiety, only the word 'price' was played back and forth in my mind.
So the price of wearing a book...
The 'no small price' my brother paid was two unavoidable deaths, right? !
Ji Luo suddenly felt so desperate.
A glimmer of life is in sight, and the future where the two can be together for a long time is close at hand.
What nonsense, met——
Seeing Ji Luo's eyes turn red, Gong Qiyan put down the things in his hand, walked up to him and patted his shoulder to help him regain his senses and relax, "Although there is no good treatment method now , but maybe in the future? Let’s start with standard chemotherapy first, he’s young and in good health, so it doesn’t necessarily mean…”
Ji Luo couldn't listen.
It's all fucking futile consolation.
It will take at least several years to come up with a new diagnosis and treatment plan!Maybe in the future?The research and development of a new drug means research and development!
Ji Luo almost wanted to bite his lips to bleed, he tried his best to restrain his body from trembling, trying to calm down, but tossing and turning, only a few large words met were amplified in his mind.
Wait, met?
"Say it again? Met expansion?" Ji Luo's memory revolving door suddenly flashed, thinking of the articles he had written before he came here.
There is also Ji Ling's report in front of him.
[met14 exon]
- I remembered.
"Gong Qiyan! Fei Xiaomet has a mutation, what kind of platinum drug do you use!" Ji Luo raised his voice and slammed the table.
Gong Qiyan looked at Ji Luo in surprise.
With a trembling voice, Ji Luo's academic articles appeared in front of his eyes.
It was an article he read when he was bored not long ago.
"The new met treatment program for non-small lung cancer has passed the third phase of clinical trials!"Nearly one million patients are expected to benefit globally》…
What is written in it?
"Traditional chemotherapy with docetaxel, plus met inhibitor targeted therapy, Gong Qiyan!" Ji Luo grabbed Gong Qiyan's shoulder and shook wildly, "Who are you scaring at night, I was almost scared to death by you—— "
Gong Qiyan did not expect Ji Luo to say such a sentence, he was a little embarrassed: "You said... docetaxel plus met inhibitors? Ji Luo, although some people in the academic circles have suggested that docetaxel is good for Fei Xiao, but now It has not been clinically tested..."
Ji Luo was taken aback for a moment, and then understood.
This should be a small difference between the two worlds.
But it's okay.
This young master is here to hang up!
Ji Luo categorically said: "Do as I say."
Gong Qiyan stared at Ji Luo for a while, and said: "Although this behavior is not in compliance with the rules, but based on our friendship, and this is a matter of your own family, I can of course submit an application material for you. But Ji Luo , are you sure? Docetaxel? ... And, the met inhibitor you mentioned, what is that? I have never heard of it."
Ji Luo: "?"
He immediately rushed to the computer and searched for met inhibitors on professional websites.
impossible!
Why not!
I have seen it in my previous life, all of which have passed the third phase of clinical trials and are available to the public, but you don’t have any here!
——Not really.
An empty browser, prompting him 'there is no search result for this keyword'!
The conference room fell silent again.
……
Ji Luo sneered in his heart.
It's up to people to plan things.
What is the price of wearing a book.
The price means that there is a chance to survive, but the actual conditions are not satisfied?
Don't talk nonsense with Master Ben.
I know what to do, but can I be stopped by some vain price?
……
Master Ji relaxed his fingers and sat in the swivel chair.
Cross your legs and cross your hands over your knees.
Ji Luo is now extremely sober.
All the articles and knowledge learned, at this moment, all clearly appeared in front of my eyes.
He raised his chin slightly, calm and arrogant.
It seems to be back to the moment when he concentrated on working overnight and teamed up with Ji Ling to kill the business world.
Only this time, the battlefield has changed.
How much suffering has been experienced.
With my brother waiting for me, I am not afraid of anything.
"If this is an ordinary person, I really can't do anything about it, but I'm different—hey, let me use your Gong Ci's laboratory and scientific research team." Ji Luo hooked his lips, "Isn't it just an inhibitor? Small meaning. For Thank you for performing the operation on him, and I will send you a scientific research problem to solve."
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