I reach the pinnacle of life by learning

The entire IBS is just a few days, and it is too extravagant to waste 1 minute.

At 3 o'clock in the afternoon, the two reached a consensus.By 7 o'clock in the evening, Qiao Yu was invited to the laboratory of the Merkel Group.

Munich is the third largest city in Germany. As a giant pharmaceutical company in Germany, Merkel spent huge sums of money to build a biological laboratory here in the last century.

Although it was established early, the laboratory is not dilapidated because of the large sum of money for renovation every year.

On the contrary, the overall design of the laboratory has a sense of technology that can only be seen in sub-movies.

Using this laboratory to simply conduct a cell tracing experiment is simply killing a chicken with a sledgehammer.

After Qiao Yu went through a simple security check, he changed into a white coat and acrylic gloves.

Among a group of Europeans, his Asian face stands out.

The C-kit+ cells and myocardial tissue just shipped from other laboratories are still in the frozen culture dish, waiting for inspection.

The staff of Merkel Millipore came to Qiao Yu's side.

"Sir," she hesitated for a moment, "Let me explain to you how to use the inducible recombinase Cre/loxp system..."

After Qiao Yu listened, he started to do it.

He picked up the pipette, took out a few milligrams of the sample solution from the centrifuge tube, and began to stain c-kit+ under the observation of the microscope.

Not far away, Charlie Michel stood in place, his expression alternately anxious and expectant.

Although he was a little anxious, he still restrained himself from taking a step forward, and only observed from a proper position to avoid disturbing Qiao Yu's operation.

Charlie Mitchell, chair of the Department of Biology at Berkeley University, was originally invited by Millipore to promote the experiment.

To be honest, as a scholar who often publishes papers on "Cell", his status in the world is not low.

However, the high academic level does not mean that the level of delivery is also high.

There are not so many brain-dead fans in the academic circle. A piece of equipment can cost hundreds of thousands or millions, and ordinary fans can't afford to write it off for the true love of scholars.

In short, except for the first day, when scholars and friends gave him some noodles, Millipore's booth was mostly empty.

This made Michelle feel very ashamed of the promotion funds she received.

Therefore, when the Merkel Group contacted him today, Michelle immediately abandoned the wine bureau and rushed over.

The staff told him that he only needed to make a judgment on the final result of one experiment.

It's just that Michelle didn't expect that he was asked to judge "whether the cardiac stem cell theory is fake".

Everyone is a mixed person in the academic circle. Michelle has had many friendly exchanges with Anvisa, the proposer of the "cardiac stem cell theory".

In his impression, Anvisa was a confident, enthusiastic and humble scholar, and he did not hold on to his identity because of many honors.

In addition, Piero Anvisa is also a tenured professor at Harvard.

He also has a laboratory named after him in San Francisco, which is used to study how to overcome the problem of heart disease. The sponsorship alone receives tens of millions of dollars every year.It is the ultimate dream of countless scholars.

"God." Michelle couldn't help drawing a cross on her chest.

Cardiac stem cell theory has been proposed for 13 years.

Before today, there have been many voices of doubt.

But Michelle is clear that these voices of doubt are just unwilling roars after numerous setbacks, and will not cause any real harm to Anvisa.

But this time, I'm afraid things will change.

When Millipore contacted him before, Michel had a deep understanding of this instant cell tracking system.

It has a creative advance over traditional cell-tracking methods in that it provides instant feedback.

In this system, the stained cells are not only colored themselves, but also the individuals that are subsequently divided will inherit the corresponding fluorescent color.

The movement process of the dyed cells in the organ will be explained clearly.

He didn't know whether to let God bless Anvisa.

Michelle opened her eyes, looking at Qiao Yu seriously and seriously.

He thought silently: "From the perspective of an acquaintance, I don't want him to have an accident. But if Anvisa is really academically fraudulent, then even if I gamble my life's honor, I will let this deceitful thief get the punishment he deserves." punishment."

"Of course, if in the end it is actually a young scholar who wants to make the elders criticized by the public opinion by clever words and tricks, so as to achieve the goal of becoming famous, I will not agree."

Michelle's will gradually became firmer.

Bernard didn't go in. As a non-professional, he didn't feel the need to conduct experiments.

He just needs to know the result.

In order to ensure the repeatability of the experiment, Qiao Yu will conduct five repeatable experiments in it at the same time.

Bernard looked at the people inside through a glass, thinking in a daze: Thomas is right, this Mr. Joe has a really good waist...

Unlike some scholars who are obsessed with theory, Qiao Yu himself often wanders around the laboratory.

Therefore, even if it is the first time to do an experiment, his operation is smooth and smooth.

Qiao Yu completed the experiment in one go, and when she put down the tweezers, she felt her arms were stiff and sore from being too focused.

Michelle took a step forward, an old face eagerly pasted on the display screen, and observed.

On the screen, the stained C-kit+ has been injected into the heart tissue of the mouse, and it starts to move.

According to Anvisa's theory, it will enter the differentiation of cardiomyocytes and begin to repair damaged heart tissue.

That's what they've observed in past experiments.

In these five groups of experiments, the heart tissues used included those in physiological steady state, those after myocardial infarction, and those with direct lesion hypertrophy.

In this system, different fluorescent labels are used for C-kit+, cardiomyocytes and other cells.

But without exception, after C-kit+ entered these hearts, there was no biochemical reaction with cardiomyocytes, and cardiomyocytes never actively accommodated C-kit+.

It is the coronary artery endothelial cells that react with C-kit+, but the repair effect is also very limited.

It is far from reaching the standard for medicinal use, let alone entering the step of human trials.

But, as far as Michelle knows.There are already desperate heart patients who have actively participated in Anvisa's human trial program.

This is not only academic fraud, but also using academic authority to kill people!

Michelle's eyes widened.

But the people around were all waiting for his reaction, not even daring to breathe too loudly.

Qiao Yu is confident in the experiment he designed, but under the infection of this kind of emotion at this time, it is inevitable to feel restrained.

"Professor." A Millipore researcher asked cautiously, "What do you think?"

It's not that he doesn't have eyes and can't see the result, it's just that he can't believe his own judgment.

Anvisa has been praised too highly, and ordinary scientific research dogs dare not question it.

Michelle took off her glasses, wiped the sweat from her temples, turned her head to look at Qiao Yu, and said in a deep voice, "Obviously, we need to expose this deception."

It has nothing to do with fame and fortune, but just the conscience of a biologist.

Today is the fifth day of the IBS conference.

The academic reports of the big cows were all sold out two days ago, and only some middle-level scholars were still shouting.

Sun Rui looked through the catalog given by the organizer, and found that today's lectures were all in fields he was not familiar with.

So, he simply lay down in the hotel until eating, and after waking up from a nap, he took Xiao Wang to the conference center.

With his hands behind his back, he stopped and walked, and those who didn't know thought it was the emperor who came to inspect his palace.

And Xiao Wang, who was following behind him with a bag, looked like a little maid in a landlord's house.

Sun Rui pretended to wander around casually, and as he walked, he came to the paper display area in the center of the hall.

The thesis books here are put away by subject. At this time, the paper books in the front row have already been taken.

The ones placed at the back also show signs of flipping.

Sun Rui's mind was moved, and after wandering for a long time, he finally arrived at the bookshelf where his papers were in full bloom.

In fact, on the first day of the conference, Professor Sun came here to see it.

At that time, he stood by his thesis, pretending to read other people's papers, and waited for someone who was destined to come here to study and discuss his masterpiece.

When the time comes, I will smile again and say, "It's just what I wrote below." I think I will surely gain a wave of admiration from international friends.

Unfortunately, Maxima is common, but Bole is not.

That day, Sun Ruizhan's legs hurt, and he didn't see anyone interested in his research.

There was even a young man who came with the professor, took it out, flipped through it casually, and inserted it back in again.

This seriously affected Professor Sun's good mood in the next few days.

The organizing committee printed a total of ten papers for him.

Now, Sun Rui counted, and there are still 10 copies left on it.

He wandered to Kou Yuhang's thesis again, and found that ten copies had also been printed, and the other party's thesis volume had already been taken.

Sun Rui couldn't help feeling sour in his heart, and couldn't help but think: what he's researching is a hot topic, and the ancestors in this field have all come to this IBS, why the organizing committee still put his thesis so biased.

However, Sun Rui regained his peace of mind when he remembered that among the participating scholars of Yanda University this time, there was another one who was not qualified to display a thesis.

He touched his hairstyle made with gel, and felt that the confidence that belonged to a straight Chinese man had returned to him.

"Xiao Wang, let's go and see where the senior brother is now. He has been here for five days, so it's time to exchange ideas." Sun Rui said.

However, at this moment, there was a sudden commotion at the entrance of the hall.

A middle-aged scholar with auburn hair rushed in, looked around, and shouted, "Where's the staff? Quick? Where's Joe's paper?!"

Sun Rui took a closer look and found that this person seemed to be an old acquaintance.

Last year, the International Symposium on Cardiac Stem Cells was held in the United States. As an expert in China, Sun Rui was invited by the organizer.There, he met the professor.The other party is from Tuao, and I heard that his ancestors have some French aristocratic blood, so he has always maintained his identity and behaved dignifiedly and elegantly. Why did he lose his composure today?

Behind him, a short bald-headed scholar quickly added: "It's not Joe, Michelle said, what I'm looking for is Zhang Kaiwei!"

It is indeed a big challenge for foreign scholars to speak Huaxia.

For example, Zhang Kaiwei's name became "Kevin Chang" in Sun Rui's ears.

So much so that he reacted for a long time before he realized that this group of people were actually looking for Zhang Kaiwei's thesis?

The staff members lowered their heads, clicked and clicked on the screen, and finally looked puzzled: "There is no search for Zhang Kaiwei's papers here, and the organizing committee may not have included them."

As soon as this remark came out, the scholars surrounding the staff suddenly let out a sigh of hatred.

The former brown-haired professor was even more frantic: "Why didn't you include such an important paper!"

Sun Rui was deeply puzzled, and said to Xiaowang, the scientific research dog beside him: "What's going on? Go and ask."

Xiao Wang rushed forward and chatted with the people standing on the edge in fluent English.

Although he was just an ordinary scientific research dog in front of Professor Sun, he had already reached the stage of a graduate student at Yanda University, so he was no different.

Looking at his peers, Xiao Wang is definitely a rare high-quality talent. He has always been the pride of his alma mater in high school, the kind who goes back to give speeches every year.

A few minutes later, Xiao Wang came back.

"Boss, they said... Millipore, the biotechnology research and development department of the Merkel Group, put up a banner at the exhibition today, saying... said..." Xiao Wang's expression was terrified, vaguely pale.

Sun Rui was impatient: "What did you say?!"

"It is said that cardiac stem cells are a scam of Anvisa, all of this is false." Xiao Wang just said this result, and his brain went blank for a moment.

He studied as a graduate student for two years and stayed in Sun Rui's laboratory all the time.

This means that he has devoted two years of his youth to the "cardiac stem cell" experiment.

This would have been a beautiful experience in his life history.

He stared at Sun Rui's face with a terrified expression: "Berkeley honorary professor Charlie Michel personally sat down and placed Zhang Kaiwei's thesis volume as a theoretical supplement...the paper volume over there has been snatched up. That's why they came here of."

"Boss, is this really fake?"

On the other side, Piero Anvisa is also facing the same doubts.

The windbreaker he was wearing today was very long, and the jacket had pockets, so he could hide his trembling hands.

In the crowd, someone yelled "Professor Anvisa is here!", and the scene that was originally full of excitement fell silent for a moment.

Familiar or unfamiliar faces around him made way for him.

Anvisa knew that he couldn't collapse yet.

As early as when he first manipulated the data, he dreamed about the coming of this day countless times in the middle of the night.

But maybe it is God's preference. In the past 13 years, although he has been questioned, he has received more honors.He also jumped from an ordinary professor to a myth in the field of cardiology today.

Anvisa's footsteps were smooth and calm.

He walked to the booth with a relaxed smile on his face: "I heard that someone questioned me again, so I'll take a look."

Anvisa stepped forward and gave Michelle a hug.

"Long time no see, my old friend. I didn't expect that the person who questioned this time turned out to be you."

Michelle's expression was still stern, but she did not refuse the hug: "Long time no see, Anvisa. Last night, I submitted the results to the editorial departments of "Cell" and "Nature". I reply, you have the last 16 hours to defend yourself."

The smile on Anvisa's face slowly faded.

At the beginning, his first paper on cardiac stem cells was published in Cell.

In 2003, the paper included in "Nature" established his status as the founder of the discipline.

He had encountered doubts before, but none of them were raised by a scholar like Michelle, and never once were the other party's evidence so convincing that he could directly ask the journal to withdraw the manuscript.

Anvisa suddenly felt bitter at the base of his tongue, and a thought vaguely appeared in his mind: this time, he might be in big trouble.

"Also, I'm not the one who discovered the problem this time." Michelle took a step back and let Qiao Yu walk in front of him, and even in front of the public, "Let me introduce, this is Qiao Yu from Huaguo Yu, you can call him Joe."