Escape From the Library

【Cell Factory-04】

The course of the School of Biological Sciences is to let them participate in the process of human birth as cells. Before that, everyone had no clear concept in their hearts, and their minds were all ignorant.Until this moment, when they heard the sound of the baby's heart beating, they finally felt the sacred feeling of "creating a new life".

In particular, the baby's heart was made by Xu Yishen himself!

The sound of regular heartbeats encouraged everyone.Yue Xingwen turned his eyes, looked at Jiang Pingce next to him, and said with a smile: "Our baby has a heartbeat!"

Jiang Pingce: "...um."

Everyone: "????"

Why is it strange to listen to the conversation between the two of you?

Ke Shaobin suddenly said: "Do you feel that the baby's heartbeat is so fast? It's more than 1 times in one minute, right?"

Liu Zhaoqing explained: "A normal adult's heart rate is 1 to 60 beats per minute, but a baby's heart rate will be very high. It is normal to exceed 70. The heart beats fast to supply blood to the baby's body and allow the cells to grow rapidly."

Ke Shaobin suddenly realized: "Oh, that's good, I'm still worried that the baby will have congenital heart disease."

Xu Yishen's voice came from the place where the heart was beating: "Don't worry, I will take care of the internal structure of the heart."

As soon as the voice fell, the mechanical voice sounded again in everyone's ears, saying: "6 weeks pregnant, the heart beats regularly, begins to divide the ventricles, and supplies blood to the fetus. The cells of the fetus divide rapidly, the embryonic form of the kidney develops, and the neural tube begins to connect to the brain. and the spinal cord begins to develop."

As the notification tone fell, a large number of pathways appeared in the "fetus" model space where everyone was located.

Xu Yishen asked: "The heart of the fetus is only divided into left atrium and right ventricle at the beginning, and it will gradually be divided into left and right atrium and left and right ventricle later on. Brother Liu, I remember correctly?"

Liu Zhaoqing said: "That's right, the atrium and ventricle are first divided, and the atrioventricular valve is formed between them to ensure that the blood can only flow in one direction without reverse flow; later, the atrium forms an atrial septum, which is divided into left and right; the ventricle forms an interventricular septum." , divided into left and right, the whole heart is considered to be fully developed. Note that the valve between the atrium and the ventricle is arched facing the atrium."

Xu Yishen said: "That is to ensure that the blood can only flow from the atrium to the ventricle?"

Liu Zhaoqing said: "Yes."

The special valve between the atrium and the ventricle is called the atrioventricular valve. It is like a switch that only opens toward the ventricle, ensuring that blood can only flow from the atrium to the ventricle. When it flows in the opposite direction, it will be blocked by the valve.

Xu Yishen quickly found the valve area, and quickly prepared the atrioventricular valve of the heart according to the area prompts.

The next moment, I heard the mechanical voice: "Please establish a whole-body blood circulation network, dredge the blood vessels in the whole body, and let the fetus form an independent blood circulation."

Xu Yishen is also responsible for the circulatory system.Hearing this, he couldn't help but said with a headache: "The blood vessels in the whole body? I can't even remember how many there are."

Liu Zhaoqing suggested: "Build the large blood vessels first, and then slowly build the capillaries later."

Yue Xingwen saw the spherical brother Xu Yishen rushing out from the heart, and began to repair blood vessels all over his body like a worker repairing a road.

Brother Xu said while practicing, "I remember that the blood circulation system is divided into pulmonary circulation and systemic circulation? I will do the pulmonary circulation first. The blood comes out of the right ventricle, flows to the pulmonary artery, passes through the arterial branches at all levels, and performs gas exchange in the alveolar capillary network. Then go to the pulmonary vein, and finally go back to the left atrium?"

Liu Zhaoqing praised: "Yes, the complete pulmonary circulation is like this: the right ventricle exits and the left atrium returns. You first repair the pulmonary artery and pulmonary vein, and the capillary network can be slowly repaired. The lung tissue of the fetus has not yet developed."

Xu Yishen let out a "huh" and began to work hard to repair the blood vessels.

Not far away, seeing Senior Brother Xu who was busy, Zhang Xiaonian couldn't help saying softly: "Building children is really a huge project, and we are about to become a human body construction team."

Ke Shaobin said seriously: "This child has condensed the hard work of 12 of us. Our child will definitely be beautiful, smart and healthy."

Xin Yan said indifferently: "And it's very edible."

Ke Shaobin: "..."

Xu Yishen quickly established the pulmonary circulation pathway, followed by the establishment of the "body circulation" pathway.

Liu Zhaoqing reminded at the side: "The systemic circulation comes out of the left ventricle, reaches the systemic blood vessels through the aorta, and then returns to the right atrium from the superior vena cava and inferior vena cava. First, repair these three main large blood vessels and reserve them later. The fetus must establish a complete The blood circulation system should be after the separation of the ventricles and atria."

Xu Yishen was busy for a while, and finally dredged all the main large blood vessels. He said with a smile, "It's really tiring to make a baby! The blood vessels are done. I will go back to the heart to split the blood cells and prepare to transport blood."

Liu Zhaoqing said, "What about the kidneys? Who is responsible for the urinary system?"

Everyone looked at each other in blank dismay - it seems that no one was assigned to be in charge of the kidneys just now, right?

Ke Shaobin whispered: "Hurry up, everyone, the baby cannot live without kidneys!"

Everyone: "..."

Xu Yishen said: "The urinary system belongs to the mesoderm. Xingwen and Ping Ce, which one of you will come?"

Jiang Pingce said calmly, "I'll do it."

The rudiments of the two kidneys are formed at the 6th week of fetal development. With the kidneys, the fetus can slowly build its own urinary system.

Although Jiang Pingce is not a medical student, he probably knows the location of the kidneys. After rolling all the way, he saw two pea-shaped signs—the library drew them in the fetal body for the convenience of everyone to distinguish the positions of different organs. The corresponding organ graphics are marked with soft blue light.

In this way, we will not let everyone create a monster baby with "a liver growing out of the heart".

Jiang Pingce quickly began to divide, allowing the cells to fill the area of ​​​​the two kidneys.

At the same time, due to Xu Yishen's efforts to produce blood cells, the blood circulation of the fetus was formally established. Everyone saw red light slowly flowing along Xu Yishen's unblocked blood vessels. With every heartbeat, the fetus began to supply blood to the whole body!

The mechanical sound sounded again in the ear to remind: "At the 7th week of pregnancy, the facial organs begin to develop, the outline of the eyes appears, the nostrils widen, and the ears are sunken. The buds of the hands, feet and limbs form, and the muscle fibers and pituitary gland begin to develop."

Hearing this, everyone started to work.

Lan Yarong was in charge of the whole body skin of the fetus, Xu Yishen reminded: "Senior Sister Lan, the skin needs to cover the whole body of the fetus, you have to follow the outline of the body from the beginning."

Lan Yarong said, "Understood."

However, the structure of the skin is more complicated, divided into epidermis, dermis and subcutaneous tissue. The epidermis alone has many types of cells. Liu Zhaoqing said: "The epidermis is responsible for the epidermis. From the inside to the outside, it is divided into basal layer, spinous layer, and granular layer. layer, transparent layer and stratum corneum, Senior Sister Lan will have to work hard, you have to differentiate into five layers of cells."

Lan Yarong: "..."

Sure enough, she saw five passages on the periphery, and each floor had to circle the baby completely.

For the baby's skin, she really worked hard!

It's just that she doesn't know the characteristics of cells in different layers, so she can only humbly ask for advice: "I start to build the skin barrier from the innermost layer, the innermost layer is the basal layer, right? What do the cells look like?"

Liu Zhaoqing said: "It looks like a column, a columnar epithelial cell."

Therefore, Lan Yarong chose columnar cells when the basal layer split, and the chubby senior sister Lan suddenly turned into a tall pillar.

Seeing this scene, Liu Zhaoqing suppressed a smile and said, "Congratulations, you changed from a spherical shape to a cylindrical shape."

Lan Yarong: "..."

She managed to finish the base layer with great difficulty, and there are four more layers to come!

Lan Yarong asked helplessly, "What about the fourth floor?"

Liu Zhaoqing said: "There are many spinous cells with protrusions."

Lan Yarong: "What about the granular layer?"

Liu Zhaoqing: "This layer, you have to become spindle-shaped cells."

Lan Yarong's voice was weak: "The second layer is the transparent layer, right?"

Liu Zhaoqing: "This layer is flat cells."

Senior Sister Lan was like a deflated ball, and instantly collapsed, turning into a flat Senior Sister Lan.Liu Zhaoqing looked a little like laughing, it was really embarrassing for her, and she changed a lot of styles.

At the last layer, Lan Yarong was already so tired that she was almost out of breath. When she spoke, her voice sounded as if she was dying: "Finally, it's the last layer... the horny layer, what else is there to change?"

Xu Yishen smiled and narrowed his eyes: "You girls often talk about exfoliating when you take care of your skin, and this is the layer you're exfoliating."

Liu Zhaoqing smiled and said, "This layer is also flat cells, thank you for your hard work!"

Sister Lan, who was flattened, finally finished repairing the outermost layer of barrier, and said with emotion: "I usually only think that the skin is very thin, but I didn't expect that human skin has such a multi-layered structure."

Liu Zhaoqing said: "This is the epidermis, and there is real leather under the epidermis."

Xu Yishen said: "By the way, the dermis is differentiated from the mesoderm. My blood circulation system is too busy here. Who will take care of it?"

Yue Xingwen took the initiative to say: "Let me come, brother tell me what I should do?"

Liu Zhaoqing said: "The dermis has many collagen fibers, reticular fibers, elastic fibers, and matrix. This layer is more complicated. Capillaries and nerves are distributed in the dermis, as well as some sweat glands, sebaceous glands, and hair follicles. With several people working together, Xingwen, you should first build up the approximate dermis barrier, and we have to fill in the vacant part."

Yue Xingwen said: "Okay."

He rolled away from Jiang Pingce's side, came behind the epidermal barrier built by Lan Yarong, and began to build the dermis. Fibrous tissue can also be responsible for the repair of the body's barriers.

Many of the fibrous structures are formed by the differentiation of cells called "fibroblasts".Liu Zhaoqing said: "Xingwen, there are a lot of fibroblasts in the dermis, you also need to change the shape."

Yue Xingwen said: "See, when I split, several options popped up in front of me. I will choose fibroblasts first, and let this kind of cells spread all over the dermis of the body, right?"

Liu Zhaoqing: "That's right."

Yue Xingwen transformed instantly after finishing the selection.

Everyone saw that the originally round and spherical Yuexing Wen suddenly turned into a flat, somewhat irregular star-shaped cell. Because the cells seemed to be squashed, there was no place in front of them, and the eyes could only grow on the "overhead".

Jiang Pingce looked down and found Xingwen lying flat on the ground, blinking his eyes on the top of his forehead, a little dazed.

Lan Yarong couldn't help laughing and said, "Oh, the flat star shape of Xingwen is cuter."

Lin Manluo also smiled and said, "Xingwen is stunned, what should I do? After being flattened, I can't continue rolling forward!"

Qin Miao said, "Can you try to climb forward?"

Lan Yarong said: "I have experience. After I became flat just now, I moved directly to the designated direction."

Yue Xingwen had no choice but to move to the side.

Everyone saw a flat star-shaped cell quickly moving sideways in front of everyone's eyes. The two big eyes above the star were very innocent and dazed.

Yue Xingwen has only one thought at this time: making a child is so tiring!