After the fourth master and I wear each other [Qing wear]

The person who first brought back news about cowpox was named Zheng Chang.

Zheng Chang led a team to Wangjiazhuang under Xiangbai to investigate a smallpox infection 17 years ago.

At that time, the emperor had not yet implemented variola vaccination in the Eight Banners.

When smallpox struck, Wangjiazhuang once became an epidemic area.About sixty people were infected, and less than one out of ten survived.

Who is asked today who was asymptomatic when smallpox struck?

There is really a group of people who have no obvious symptoms, and they are farmers who are responsible for raising and milking dairy cows.

"At that time, I didn't pay much attention to this phenomenon. I just thought that the group of people were protected from infection because they had no contact with the patient."

When Zheng Chang came to the Beijiao Manor, he was a little surprised that the person in charge here was actually Wu Gege.

Although it was unexpected, he got the fourth master's oral order and reported it in detail.

This meeting will be held in an open and aboveboard manner, with the nuns guarding the side and guards standing guard outside, it cannot be called a private meeting at all.

Although Wu Gege looks quite young, Zheng Chang dare not neglect at all.When reporting face to face, he could really feel the coercion brought to him by the other party.

Zheng Chang went on to say, "The servant went here to verify that cowpox broke out in the cattle farm a year before the smallpox epidemic. It was the first time that the farm raised cows in batches, and the farmers were deeply impressed by the concentrated disease of the cattle."

In order to avoid losses, a lot of manpower was invested to take care of the cows, and the group of cow farmers had to directly contact the pox-prone parts of the sick cows.

According to the memories of some people, after contact with sick cows, people also have similar acne.But the symptoms will disappear soon, without too much discomfort.

Zheng Chang asked item by item according to the list of questions given by the fourth master before departure, and determined that the cattle farmers in Wangjiazhuang were the survivors he was looking for.

After Yinzhen listened to Zheng Chang's report, this person's written record was more detailed.

There were a total of 21 cattle breeders in Wangjiazhuang back then, and none of them showed obvious symptoms when smallpox struck.

Seventeen years have passed, and there are still 17 people alive, and the youngest is over 15 years old.Ten of these people clearly remembered that they had had cowpox, and the rest could not remember because of the age.

In the days that followed, sporadic outbreaks of smallpox appeared.Among the cattle farmers, three had contact with someone infected with smallpox, but they did not get sick either.

Zheng Chang selected the three smartest from the ten people who had clearly suffered from cowpox and brought them back to the capital.

In addition, there happened to be a sick cow with pox on the farm again, and it was bought back according to Si Ye's previous order.

Yinzhen asked carefully, "This group of cattle farmers have been in direct contact with sick cows. They have had cowpox. What about their family members? Will cowpox be passed from cowpox to people, and will it be passed from patients to people?"

Zheng Chang shook his head, "Back to Wugege, the servants investigated the Wangjiazhuang area and found no relevant records. Those farmers are not sure whether their family members had cowpox 17 years ago, maybe because the disease is mild and they have no memory."

Yinzhen was not surprised by this.

Zhuanghu is not a doctor who specializes in research. If he is seriously ill, he must have a memory, but it is normal for a mild illness and a long time to forget it.

On the contrary, this shows that Zheng Chang's investigation is true and not fabricated.

The surname of the steward of Zhuangzi in the northern suburbs is Liu.

Yinzhen first asked Guanshi Liu to arrange the people and cattle that Zheng Chang brought to the capital.

Then, send someone to bring the relevant investigation content of Wangjiazhuang and today's exercise experience back to Baylor Mansion.

This is by no means obedience to Wu Fuyi.

Yinzhen did not write three thousand words of experience every day as the old ghost wished, but only a short one hundred words, which simply means that he has exercised.

People like him will never be embarrassed by mere running.One hundred words is like signing in regularly, proving that he can persist.

He even dared to assume boldly that he runs here every day, so he doesn't know if that Wu Fuyi exercises every day?

The so-called ebb and flow is whether one day they can win the opponent in speed.This question may be verified in the near future.

Of course, it will take at least three months to try this kind of hypothesis again, and will not show the slightest thought until that day comes.

In Baylor's mansion, Wu Fuyi received a letter.

After reading the exercise experience written by Yinzhen for seven days in a row, the content is very boring and boring.Keep a record of how many miles you run every day, what time you run, and how long you run.

With such a barren text, the homework of elementary school students in later generations will fall into the category of failing.

I can't pick out the advantages. Yes, typos should be.Except that Yinzhen has completely imitated Wu's handwriting, there is no other place to praise him.

If you want to torment others, if you plan to write a letter to Yinzhen, you must express your feelings in the next article.

However, this idea was interrupted, because the letter came with the first Wangjiazhuang article on the conclusions of the vaccinia investigation.

Obviously, the vaccinia report saved Yinzhen.

Wu Fuyi saw that the dawn of not going to court was approaching, but he did not rush forward hastily.

The conclusion of Zheng Chang's team alone is not enough. Fifty team leaders have been spilled out, and we need to wait for them all to return to the capital.

After summarizing all the investigation contents, go to Kangxi with detailed circumstantial evidence.

This time, the Lantern Festival will pass.

In the blink of an eye, it is the 22nd of the first month, and it is written in the almanac that it is suitable to move.

"Your Majesty, Four Baylor begs to see you."

After the early dynasty, Liang Jiugong passed on to Kangxi.If he remembers correctly, in the past four months, the fourth elder brother seldom went to the Qianqing Palace to ask for an audience.

"Pass him in."

Kangxi put down the brush in his hand, and roughly guessed what it was for. The fourth child should be pleading guilty for the farce in the mansion on New Year's Eve.

After Wu Fuyi entered the hall and paid his respects, he indeed first mentioned the crime of Mama Mama on New Year's Eve.

"The minister is not good at running the family. Mashi is so bold as to murder the royal family. I ask Khan Ama to punish him."

"I know."

Kangxi had heard about it a long time ago, and he didn't give any glances at Mama Ma, Haishi and the like, as long as the child was safe.

"Mr. Ma has committed a heinous crime, and death is not a pity. It has nothing to do with you. The children have not had any accidents, so it shows that you have put your heart into it."

Although he didn't care much about it, he affirmed the attitude of the fourth child to report the housework. This kind of idea of ​​not hiding it is a good idea.

However, Kangxi didn't want to let the matter spread again. If something bad happens to someone's family, there is no need to spread it around and become the talk of other people.

"This matter ends here, don't let your mother and concubine worry about it."

However, Wu Fuyi wanted to make a little use of the topic, "What Ahma Khan said is very true. Raising a child is hard work, and I feel ashamed that I have never learned the skills of raising a child from Ama Khan. Although Fujin has done his best to help, but at present Having four children is probably not taking care of them well. It would be great if there were less Haishi in the backyard."

"You..."

How could Kangxi not understand, this is because he dislikes the chaos in the backyard when there are too many people.

Hong Hui was almost murdered in the fourth family, and they just had a young son, so it's normal to think so.

"The draft just ended in September last year, and there are still two or three years left in the next round. Now you can say that you don't want anyone. Okay, it's important to raise the children first."

Kangxi gave a verbal promise, and his son didn't marry Fujin, so it doesn't matter whether he refers to the new Princess or not.

"Thank you Khan Amma for your grace."

Wu Fuyi didn't know how long Kangxi's oral order was valid.

Anyway, she is now a wife, concubine and children, which is really enough.I also don't want to focus on the disputes in the backyard. There are as few people as possible.

Kangxi looked at the fourth child, he also apologized, thanked Xie En, why didn't he intend to leave?

"Is there anything else? I'm going to the study later to see your younger brothers' homework. If you have something to say, speak up quickly."

Wu Fuyi took out the report related to the vaccinia investigation from his sleeve.

It is the summary report that aggregates all the investigation teams.The first draft written by Yinzhen, I revised it as appropriate, and it was time to appear on the imperial case.

"It's time for Erchen's eldest son to be vaccinated this year, but Honglin's body has not been strong enough since he was born."

Wu Fuyi slowly revealed the motivation for vaccinia research that he had initially discussed with Yinzhen.

Starting from worrying about Hongying, he also mentioned the vaccination of the fourth elder brother when he was a child, recalling the little bit of care that Kangxi once gave.

The core idea is that Kangxi set an example of a good father, so that sons also want to try their best to follow suit.

Then, in the ancient book "Tianwen Sulu", I saw the article "Qingniu Shenli", which said that the Qingniu with pox saved the people who were ravaged by the smallpox epidemic.This triggered thinking, and wanted to explore the relationship between cowpox and smallpox.

"There are many cattle farmers in Gyeonggi. I think it's better to investigate. Even if I think in the wrong direction, it will cost me a little money at most."

Wu Fuyi said with a little joy on his face.

"Blessed by Tohan Amma, this investigation has really yielded some results. It is reported that anyone who has been infected with cowpox has no symptoms when the smallpox epidemic hits."

At this point, she threw out the most critical conclusion, "When people get vaccinia, the symptoms are mild. Compared with the discomfort when inoculated with human pox, it is much smaller.

If getting vaccinia once can also prevent smallpox, then changing human pox to vaccinia can avoid many risks of vaccination in previous years. "

Kangxi originally thought that the fourth child mentioned childhood vaccination in the hope that Honglin could postpone the vaccination, but he never thought that he was throwing out such a bold hypothesis.

At this moment, the fourth child came up with the new method of vaccinia. This son has been quite calm since he grew up, and he has never been whimsical.If it were another person, such as Fourteen, it would be suspected that he would drive people out directly in daydreams.

"Yinzhen, do you know what you're talking about!"

Kangxi's tone was severe, "The technique of human pox has a long history. It began in the Tang and Song Dynasties. It has been improved by famous doctors in the past. It has achieved today's results. It is unheard of to replace it with cowpox."

Wu Fuyi observed his words and expressions, and although the emperor looked serious, he didn't have many doubts.

Anyway, word-of-mouth is very important, and Yinzhen's more than ten years of refraining from haste and patience has successfully created an image of being reliable.

The image created in the past has come in handy now.

Wu Fuyi had the opportunity to speak slowly, "Responding to the words of Ama, I know that this statement sounds absurd at first glance, but there is no need to favor the past and underestimate the present. The ancients did not record the cowpox technique in books. There may be various reasons." .”

This enumerates various possibilities, the first is whether dairy farming is widespread.

Those who came into contact with the sick cows were all low-level people. They got vaccinia and became immune, but they were not necessarily known to others.

On the contrary, most of the people who can afford milk are wealthy families with spare cash.Only those who have money can read and read, and explore the source of pathology, but the probability of them coming into contact with sick cows is low.

In addition, the scope and prevalence of smallpox in the past dynasties are also one of the influencing factors.

If it is only spread in a small area, people already have varicella, and they may not necessarily study new methods.

At the end of Wu Fuyi's speech, he praised Kangxi.

"Even though the pox technique was developed in the Tang and Song Dynasties, it was not popularized on a large scale. For hundreds of years, only Khan Ama has made great efforts to promote vaccination. Such a feat is unheard of. But if you dare to do it, your name will surely go down in history."

Kangxi's expression remained unchanged, but his heart was full of joy.

That's a good point. The promotion of human pox was done under pressure.In the beginning, those courtiers said that this was wrong and that was wrong, so they simply let the older brothers do the vaccination first, and this matter can gradually be promoted in the Eight Banners.

The effect is remarkable. In recent years, there has been no large-scale outbreak of smallpox in the Eight Banners, and even Tsarist Russia has come to learn vaccination.

But there is always a fly in the ointment.

There are risks in varicella surgery, and some children will die if they can't get through it, and not all children from the Eight Banners are eligible for vaccination.

During the period from inoculation to pox outbreak, the vaccinators are almost infected with a smallpox, and they themselves become the source of transmission.If the people caring for them have not had smallpox, they are at risk of infection.

In addition, one of the side effects of vaccination against human pox may leave a large area of ​​acne scars.

Kangxi himself suffered from smallpox, leaving many acne marks on his face.He is the emperor and a man, of course it is not a big problem, but it is different for a woman.

Also because of this reason, although variola surgery was promoted in the Eight Banners, the vaccination rate of women was lower than that of men. ①

If there is a low-risk vaccinia that can replace the high-risk human pox, it will undoubtedly be great news.

Despite expectations, Kangxi is still cautious.

At that time, he promoted the smallpox technique, which was to promote the vaccination technique that had been medically proven for hundreds of years.In comparison, vaccinia is a brand new method and cannot be made public hastily.

He gave Liang Jiugong a look and asked him to go and get the brochures prepared by the fourth child first.

At the moment, Kangxi flipped through the "Discrimination and Analysis of the Relationship between Vaccinia and Smallpox Prevention".

The memorial is very clear, covering almost all cattle farms in Gyeonggi, and surveying thousands of cattle farmers.

Various aspects were involved, such as the contact between humans and sick cows, the different conditions of smallpox infection when it was raging, and whether one time of cowpox could get rid of smallpox infestation for many years, etc.

For a while, Qianqing Palace became very quiet.

Kangxi flipped through this thick memorial verbatim, and the more he read it, the more he felt that as long as the records were true, it was not nonsense to use vaccinia to prevent smallpox.

Before I knew it, nearly half an hour passed.

He didn't recover from the detailed data until he read the last word.Looking up, he saw the fourth child standing respectfully.

This time, it was really not intentional to leave his son alone, but the content of this memorial is too important, and he forgot to tell the fourth son not to stand if he was not paying attention.

"Liang Jiugong, what's the matter with you slave, let Sibeile stand for a long time, why don't you hurry up and serve tea."

Kangxi couldn't say that he forgot, so he could only reprimand the chief eunuch angrily.

Turning his head, he pointed at the fourth child with a smile while holding the memorial. "You are also stupid. There are chairs in this hall, and you don't know how to sit down for a rest."

Does Wu Fuyi not want to sit?Certainly not.She just wouldn't be so stupid as to sit down without the emperor's will.

It doesn't matter if you stand for nearly half an hour, it's just like exercising.At the moment, Kangxi has such a pleasant attitude because he has already believed in the efficacy of vaccinia.

"Thank you Khan Ama for your seat."

Wu Fuyi will sit down now, and he is more concerned about whether Kangxi still has the courage to do vaccinia research.

Kangxi put down the memorial, "Tell me, what do you want to do next? Although you have done detailed investigations, there is still insufficient evidence in the end."

"I would like to ask Khan Amaen to allow a small-scale inoculation experiment with vaccinia first."

Wu Fuyi revealed the plan, "Choose 30 death-row prisoners, and ask them to have never been vaccinated against smallpox or vaccinated. Inoculate these people with vaccinia, and when the vaccinia symptoms subside, give them vaccinated again."

To vaccinate is to actively infect with a mild form of smallpox.

"In the past, there were various pox reactions when vaccinated against human pox. If those people were inoculated with vaccinia first and then varicella, those people had no symptoms, which is a preliminary verification of the efficacy of vaccinia."

Wu Fuyi said it was a preliminary verification, but further verification is still needed.

"Afterwards, the second step is to let them be directly infected with strong smallpox. If successful, the number of experimenters will be further expanded."

In this era, using death row prisoners as the first batch of experimenters is the most suitable choice.After that, the scale of the experiment will be expanded, and people who can pay for the voluntary experiment can be recruited.

Kangxi thought that the fourth child was working in the Ministry of Criminal Justice, "Do you have a list of candidates for death row?"

"Not yet."

Wu Fuyi actually read through a lot of files, and also listened to Yinzhen's suggestion to draw up a batch of lists, but both of them decided to say no when Kangxi asked.

It's good to have a plan.

However, if every step is planned for major events, in the eyes of the emperor, it is not necessarily prudent, but rather scheming.

Wu Fuyi showed a little shame, "The study of vaccinia is a bold move. Even if the investigation is detailed, without Khan Ama's guidance, I will inevitably have no idea. I am looking forward to your support."

Kangxi's eyebrows were more gentle, and his dependence on his son was quite beneficial.

"Draw up a list as soon as possible. Twenty to thirty people, this number is not too much or too little for the first experiment, and it can be placed on your Zhuangzi.

The person you choose should first have a simple background, and be divided into several groups.Young, old, healthy, and weak, plus a few female prisoners. "

Now that you decide to conduct an experiment, you must take various factors into consideration.

Kangxi looked at the memorial and said that the fourth child had already bought ten sick cows and put them in Zhuangzi in the northern suburbs.

Since the fourth child proposed the experiment, and he is also prudent in his work and sincerely wants to find out the cowpox, let him be the person in charge of this experiment.The location of Zhuangzi in the northern suburbs is also appropriate, that area is relatively remote, and people usually don't go there for leisure and entertainment.

"Death row inmates are heinous people after all. Go to your village and lock them up. You need more guards."

It is impossible for Kangxi not to send guards, this is also to ensure the safety of the fourth child.

Speaking of guards, this task has to be done in a low-key manner at present, and it is very particular about who is assigned.To be capable, the relationship with Sibeile should not be too rigid, lest things go bad.

Kangxi asked: "Fourth brother, do you have any candidates to recommend? You don't avoid relatives in the internal selection."

Wu Fuyi didn't want anything in particular, but she and Yinzhen both had guards they didn't particularly want.

The truth has to be countered.

"I heard that Longkodo thoroughly investigated the wolves incident in Mulan Paddock. He worked so hard to return to the capital a few years ago, but there were no more clues. Longkodo came to the door several times to send condolences, saying that he was ashamed of his trust in Khan Ama. It caused my son and ninth brother to be injured, I feel very sorry."

Wu Fuyi said, as if he had forgiven Longkodo long ago.

Kangxi raised his brows slightly, "So, you want him to go to Beijiao Zhuangzi to guard?"

"It's not a good job to guard the prisoners in the vaccinia experiment. It stands to reason that Longkodo wants to pay off the crime with all his heart, so it's not selfish for my minister to recommend him to do this job."

But Wu Fuyi changed the subject, "It's just that Longkodo is in Tong's house during the New Year's Eve, so it's inevitable that he will be greeted and sent off by many people. Letting him guard Beijiao Zhuangzi might cause those people's guests to be angry." Note, this is a bit ugly."

Enough said here.

Wu Fuyi didn't say who he wants to replace Longkodo, "I can't think of any other candidates, so I ask Khan Ama to decide."

Kangxi groaned slightly when he heard this, it doesn't matter if the fourth child forgives Longkodo, it's not a good thing to hold grudges too much.

He wanted to give Long Kedo a chance to recover, but he hoped that the chance should not be an intercession from his sons, because he didn't want his sons to be too deeply involved with the Tong family.

Fortunately, the fourth child can see clearly that guarding the cowpox experiment should be as low-key as possible.

Obviously, it is not suitable for Longko to go more if there is this one. There are many activities during this New Year's festival.

Who to choose?

Kangxi didn't think about it for a while, but he decided on one thing.

"Later, I will determine the candidates for the guards. You will hand over the list of death row prisoners in the past few days. After that, you don't have to go to the Ministry of Criminal Justice. Twelve and Fourteen got married last year, and their mansion has also been repaired. You Take over this matter and be responsible for the construction of the mansions of the two younger brothers."

"Yes, my son obeys the order."

Wu Fuyi agreed very quickly, and couldn't restrain his joy at hearing the transfer.

Instead of going to the Ministry of Punishment, he took over the task of repairing the mansions of Yinxuan and Yinzhen. The subtext of this sentence is that Kangxi asked the fourth elder brother to concentrate on conducting vaccinia experiments in the northern suburbs.

what does this mean?

Outsiders seem to have lost the real power of the six departments, but its hidden benefits are great. If you don't have government affairs, you don't have to get up early every day to go to court!

How could Wu Fuyi be unhappy.

Thanks to my hard work, I finally got this day!

Kangxi never imagined that someone would be extremely happy because he didn't get up early.

At the moment, seeing the cheerfulness of the fourth child, and not being displeased at being deprived of the real power of the Ministry of Punishment, it is taken for granted that he really wants to handle the cowpox matter well.

Lenovo's fourth child's initial motivation for studying vaccinia was to vaccinate Hongyi.

There will be this kind of consideration, the reason is that I was with me when the fourth child was vaccinated, and I couldn't help but feel a sense of pride.

At this moment, Kangxi looked at the fourth elder brother and secretly thought that he is indeed my son, he is like his father, and has a noble character.

I am in a good mood to say a few more words. "You are in charge of the renovation of Twelve and Fourteen's mansions, and don't spoil them. You don't need to add whatever they want, especially Fourteen. Remember, what I said, don't spoil him too much. "

"My son, I would like to obey the holy edict."

Of course Wu Fuyi accepted the order.

Looking at Kangxi today, I feel that he is a bit pleasing to the eye, so I said this sentence first.

Next, Fourteen wants to add good things to his new home, so he should know what "brothers and brothers respect".I don't know if Yinzhen will ask for help.

The author has something to say: ①This is a private setting of this article!No exact data found!

When promoting smallpox, it is said that all children of the Eight Banners are required to be vaccinated.However, it was recorded in the palace that it was the older brother's vaccination system, and the situation of the princess was not found.

In addition, the order of the children in Si Age's Mansion is also a private fiction.