Sleepless Doctor

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"Mr. Wu, I have read a report saying that 301 has begun to study the hypothalamic fornix nucleus microelectrode to treat Alzheimer's disease. I think your lower microelectrode is also located in the hypothalamic fornix nucleus..."

The people who came to observe the operation were sent away. Several people from Jianxie Hospital returned to the ward. Zhou Guohui asked as they walked.

"Director Zhou, you are too polite." Wu Mian was taken aback and smiled, "Don't call the teacher, you are kidding me."

"Oh." Zhou Guohui sighed, "The expert is respected, and should be respected. After reading your postoperative effects, I have a feeling that the patient can recover at least 70% of the function and memory after the anaesthetic has passed completely."

"When I was in school, the teacher Zhuang and you were classmates. You call me that. How will I return to Xiehe in the future?" Wu Mian scratched his head and said.

"These are all trivial matters." Zhou Guohui asked, "Are you in contact with 301?"

"Yes, there has always been a connection." Wu Mian nodded. "In 1985, Professor Turnbull used electrical stimulation of the basal nucleus to treat dementia. Stimulation therapy can improve the glucose metabolism of the ipsilateral temporal lobe and parietal lobe, but it cannot improve the patient’s cognitive function, so this study was delayed for some time."

"The delay was 23 years. Until 2008, when Dr. Hamani was studying and treating obese patients, he accidentally discovered that electrical stimulation of the hypothalamic fornix nucleus can improve the patient's memory. After a series of experiments, it was preliminarily determined that deep brain stimulation was used to treat dementia. The effective target is the hypothalamic fornix nucleus."

"In a phase I clinical trial, electrical stimulation of the hypothalamic fornix nucleus in patients with mild to moderate dementia for half a year to 1 year showed that electrical stimulation of this area can alleviate or improve cognitive decline and improve brain glucose metabolism. ."

"In the future, in 2011, Dr. Ponce conducted a clinical phase II trial study on 42 patients with dementia. Early safety studies showed that the implantation of DBS electrodes into the hypothalamic fornix nucleus is safe and reliable for the treatment of dementia."

"There are two difficulties that cannot be resolved. The first is that the target of the hypothalamic fornix nucleus is located below the lateral ventricle, and the third ventricle is anterior to the lateral ventricle. The implanted electrode must pass through the lateral ventricle.

Since the tip of the implanted electrode is thicker and blunt than the microelectrode, after the recording of the microelectrode is completed, the tip of the implanted electrode is likely to slide along the lateral ventricle wall when it passes through the lateral ventricle wall, which affects the accuracy of the target. "

"In 2013, the 301 research team used trocar-assisted puncture technology to solve this problem. The next difficulty to face is positioning. Two years ago, General Medical produced a magnetic resonance system. The DST surround matrix gradient system is a magnetic resonance system. Breakthrough technological innovations in the field over the past ten years have made precise positioning possible."

"Every technology is created from scratch, and countless people have studied it and built it little by little." Wu Mian said with a smile, "I just solved the last part of the puzzle, nothing."

It's nothing, these three words speak lightly, but Zhou Guohui knows how heavy it is.

"Mr. Wu, great!" Zhou Guohui praised sincerely.

Wu Mian did not continue to talk to Zhou Guohui about calling him his teacher.

Back in the ward, Gao Baixiang squatted in the ward, always observing the postoperative state of the patient.

Because the neurology ward has not yet been established, I can only deal with it here by Gao Boxiang.

The overall diagnosis and treatment process of Jianxie Hospital is not formal. The old driver drives a new car, and Wu Mian doesn't really care that the patient must be hospitalized in neurosurgery.

This is not the case, Zhou Guohui "threw himself into the trap" and took refuge from the imperial capital. 361 reading

Come, easy; want to go, hard.

Wu Mian will never let him go, like Zhou Guohui, a chief physician, department director, and deputy director of the Neurology Society like Zhou Guohui. And now, after seeing a patient treated for Alzheimer's disease, he will not leave in a short time even if he is driven away.

"Mr. Wu." Seeing Wu Mian's return, Gao Boxiang stood up and greeted him immediately.

"Well, you go and rest." Wu Mian smiled, "I'll watch it here."

The postoperative magnetic resonance of the patient showed that the current conduction of the brain nerve bundles had spread widely. Zhou Guohui said that at least 70% of the function is not without a target.

It's just that the patient has been sleeping after general anesthesia, and he has not yet woken up. What was the specific effect, Wu Mian didn't want to miss the first-hand information.

Gao Boxiang also knows that he is not a professional neurologist, and recently as the free operation of congenital heart disease spreads, more and more patients come for consultation and hospitalization.

Cardiac surgery is Gao Boxiang’s main battlefield. Coupled with the cooperation with thoracic surgery for mitral valve surgery, Gao Boxiang is also very busy.

After sending away unrelated people, Wu Mian sat beside Chu Zhixi, looking through the glass at the sleeping elderly man inside.

Yuan Wei was a little nervous. The muscles on his face were tense in the deep city, without a trace of smile. His eyes were narrowed and he stared at the grandma in the single room.

"Mr. Yuan, don't be so nervous," Wu Mian said, "Vital signs are stable and you will wake up soon."

"Doctor Wu." Yuan Wei wiped the trousers with his hands, and the two water stains were clear. "I have also seen the nuclear magnetic image. Although I don't understand medicine, I know that I can do it by looking at the image."

"Um."

"I'm worried that when Ama sees me when she wakes up, what should she do if she cries loudly? Will it cause arrhythmia? Not long after the heart surgery...I regret to stay here for 20 days longer, let Ama adjust to it. Do…"

Yuan Wei nagging, completely lost the gloomy and cruel spirit of the once underground chief. He is like a family member of an ordinary patient, looking forward to the effect of the operation to exceed his expectations.

At this point, people and people are the same and common. UU reading www.uukanshu.cóm

"The heart is okay." Wu Mian said, "Before the operation, related examinations have been done, and the chance of complications is not high. It's not that you said that you want to have the operation, but I don't have principled consent. The patient is in a bad state. You can't worry anymore."

"Haha." Yuan Wei rubbed his hands, the calluses rubbed against each other, making a rustling sound, like the wind blowing over the sand on the beach.

"It's good for my grandma to remember me." Yuan Wei looked at grandma and said, "I don't have any relatives in this world, and I'm used to cheating, thinking that I am invulnerable. The time when grandma gradually didn't know me...Wu Doctor, you don’t know how sorry I was at that time."

"I was thinking about working hard outside so that Ama could live a good life. I had suffered a lot in the first half of my life, and it won't work in the future. But now the life is good, but Ama doesn't remember anything, and I feel panicked."

Yuan Wei revealed his concern, as he was talking, Wu Mian suddenly stood up and strode into the ward.

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