Tech Translator
Chapter 181 Blood Manufacturing Method
When Zhou Yunsheng saw that they had finished speaking, she said directly: I don't quite understand what you are talking about, let's go and see how blood is made.
She looked at Du Xianyu again and asked, Director Du, have you applied to the CFDA for the blood products we know?
I informed Wang Tong that he sent someone to take the samples and said he wanted to apply to the China Food and Drug Administration. I didn't ask in detail how long it would take for the results to come out. Du Xianyu simply replied.
Oh, why didn't I receive the news. According to the procedures stipulated by our company, they have to report, and I should receive the news as soon as possible. If they don't notify me, the mobile phone software of the Food and Drug Administration will also notify me. Zhou Yunsheng said strangely.
At the same time, she took out her mobile phone and clicked on the cloud intelligence platform. After reading it, he said in relief: It turns out that they are in the process of applying and have not yet formally submitted for approval. This product is no longer on the priority list and needs to be queued.
After Zhou Yunsheng finished speaking, they wanted to go to the place where blood and blood products were produced.
It can be seen from Du Xianyu's words that the blood production technology is now mature and can be industrialized at any time.
Under the leadership of Du Xianyu, they walked along the glass corridor of the biology laboratory. Walk to the laboratory responsible for manufacturing blood and its blood products.
Li Hao saw that they could easily see the scene in the laboratory through a transparent glass wall.
There is nothing special in the laboratory, except that there are many large glass culture tanks in it. Most of the liquid in the jar is colorless and transparent. Only two large jars are the most special, one is dark red and the other is light yellow.
An experimenter who just wanted to enter the laboratory saw Du Xianyu and Li Hao standing here and came over to say hello to them.
The experimenter holds a glass box containing slow experiment materials in his hand and wants to enter this laboratory.
He first went to the glass room next to him to change into the protective clothing he was wearing, and then a blue-purple light lit up on the roof of the glass room.
Zhou Yunsheng looked curious, and asked Du Xianyu: Is this the way they kill viruses?
Du Xianyu introduced to her: This is sterilized by high-intensity ultraviolet rays, and dust is removed by electrostatic. It is guaranteed that no pollutants will enter the laboratory.
Zhou Yunsheng stared at the way the blood was produced in the laboratory. She pointed to the laboratory and said: This looks very simple, and I saw that their operation is not complicated.
It looks very simple, but the technology contained in it is very complicated. We only found the best ratio after tens of thousands of experiments.
Blood is no other substance than it transports the oxygen, nutrients and wastes that the body needs.
A slight difference in the composition of each component will cause the rejection reaction of the organism. The most severe rejection reaction is to immediately drain the blood and replace it, which cannot be stopped. The mice died after a few minutes.
The core technology of our blood is the ratio of various components, which is more important than hematopoietic stem cells.
In particular, the storage time of blood should also be considered. Adding our special additives can preserve its time as best as possible without affecting the efficacy of blood.
Now we produce blood, it can be stored for about 60 days.
Li Hao saw the densely packed large jars in the laboratory. He didn't quite understand how blood is made, so he asked Director Du, Director Du, can you briefly talk about how blood is made.
Pointing to the laboratory equipment, Du Xianyu said: We also use the principle of bionics to imitate the generation of blood in living organisms.
We start with highly active cells obtained from living organisms. Using certain technical means, induce it to differentiate into hematopoietic stem cell progenitor cells.
This progenitor cell is what the embryo produces around day 10. It has a high degree of differentiation ability and can not only differentiate into blood-related cells.
It also has the function of differentiating into lymphocytes. It's just that the human body's immune system is too complicated, and it's a very delicate system, and a slight mistake can have a great impact on the human body. We haven't found a role for lymphocytes yet.
Hematopoietic stem cells are then differentiated from hematopoietic stem cell progenitors. Hematopoietic stem cells, through certain conditions, differentiate into blood cells such as red blood cells, white blood cells, and platelets.
Du Xianyu pointed to the red glass jar and said: This is the place where red blood cells are cultivated. The cells we cultivate are basically the same as those in the human body. After animal experiments, they can transport oxygen.
He pointed to the light yellow culture tank and said: This is blood plasma. Its light yellow appearance is due to the bilirubin in it. The preparation of blood plasma is the most difficult for us.
As long as the blood cells are done with the hematopoietic stem cells, the rest is a matter of course.
However, it is extremely difficult to configure plasma, and the composition of plasma varies slightly from person to person. We can only find the largest common divisor to ensure that plasma will exist safely and stably in any human body.
About 90% of it is water, and there are some trace elements and a variety of proteins in it. After the human body lacks other substances, it will naturally be produced.
In addition, there will be no people who have all their blood drained and are still alive. So less substances will not affect its effect.
Plasma and blood cells are mixed together according to a certain ratio, which is our artificial blood.
Du Xianyu sighed, and continued: Our artificial plasma can only replace two-thirds of the blood at most. It has many trace components that we haven't studied thoroughly yet.
We experimented with a mouse, drained its whole body of blood, and replaced it with the blood we made. Afterwards, she was still able to live a normal life, but she seemed listless and not lively at all.
After experiments with various animals, we found that when 80% of the whole blood is replaced by artificial blood, the organisms will have side effects.
Zhou Yunsheng looked at the blood manufacturing laboratory, and she always had a question. After hearing what Du Xianyu said, she immediately asked: Director Du, we have six blood types, and I think there is only one blood type in this big jar. Other blood types How patients use it.
There are 34 blood types in the human body. We have arranged them. They are in other laboratories. Hematopoietic stem cells are prepared for each blood type.
The main blood type detection methods are ABO and RH, but the mixing of other blood types can also have adverse consequences for people.
From the beginning of manufacturing this technology, we strive to be comprehensive to ensure that enough blood can be produced for each blood type.
Zhou Yunsheng covered his mouth and said, It turns out that human beings have 34 blood types. I always thought that the only blood types are ABO and RH.
After they visited the blood manufacturing laboratory, Li Hao and Du Xianyu separated. Du Xianyu continued to inspect the progress of each laboratory.
Zhou Yunsheng took Li Hao to the medical team. She said she would go to the ophthalmologist Dr. Qian Minghua to help Zhou Yuanyuan inquire about the eye transplant.
I also want to take Li Hao to find Li Deren, an old Chinese doctor, and say that Li Hao has been in poor health recently. It just so happens that the company has an old doctor of traditional Chinese medicine with excellent medical skills, who wants to take good care of his body.
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