The Godfather of Surgery

The regional competition of the Golden Knife Award is proceeding in an orderly manner, the competition is becoming more and more fierce, and the harsh scores make it more and more difficult to obtain full marks.

Yan Jiejun of Attached 2 and Su Fengyu of Attached 1 fell out of the full score camp in the third batch of operations, and they made the same mistake.

In an operation for comminuted fracture of the lower end of the humerus, a young female patient was deducted for the wrong choice of sutures for the cosmetic suture of the incision.

In fact, the joint part was a contraindication for cosmetic suture in the past. The advantage of cosmetic suture is that there are fewer scars, but the disadvantage is that there is no regular interrupted suture to be firm.

Joint surgery requires early rehabilitation training after surgery. Generally, rehabilitation training should be started on the second day after surgery, so as to obtain satisfactory joint function.

The firmness of cosmetic sutures is poor, which cannot meet the needs of early rehabilitation training, and it is easy to cause incision cracks during activities.

Now the cosmetic suture technology is getting better and better. If each stitch can hook enough dermal tissue, it can be firm in the early stage, and the original contraindication will become an indication.

Yan Jiejun and Su Fengyu have no problem with cosmetic suture techniques, but unfortunately their mastery of surgical suture techniques is not comprehensive enough, and their understanding of various sutures is insufficient.

For cosmetic sutures, they use absorbable sutures, which is actually a mistake most surgeons make.

Many doctors even call absorbable threads cosmetic threads, which is completely wrong.

At present, the choice of sutures for cosmetic sutures must be non-absorbable slippery threads, such as thin nylon threads with needles, which need to be removed after surgery.

Although absorbable sutures do not need to be removed, they are used to sew the skin. During the absorption process, foreign body reactions and inflammatory reactions will occur, resulting in more obvious scars, which are contrary to the purpose of beauty. Thin nylon threads do not have this problem. After a few days , or demolished after ten days.

If it is normal operation, this is not a problem, but in competition, we must pursue excellence.

After the third batch of operations, Song Zimo, Su Nanchen, Lin Hao, Chen Ge, and Cao Qian still maintained full marks.

The strength of the teams from other provinces in South China still lags behind that of Nandu Province, and there is no full-scoring team.

Lin Hao has a sense of urgency now. After three rounds of surgery, Yang Ping's team has not been thrown away. They are still tied for the first place in the South China Division with him.

Yang Ping knew very well about Song Zimo's level. This first aid would have no opponent in the regional competition, but in the national competition, he could swept him for a while.

Unfortunately, more than half of the operations performed by the chief surgeon in the national competition must be performed, and the final surgery must be performed by the surgeon himself.

So Yang Ping is not in a hurry now, as long as the points are not behind, he does not intend to come forward for the time being, and he seizes the time to do more important things.

A project plan has been written for the research on human muscle growth in the stem cell laboratory.

All these days have been spent here, and the more than 100-page project plan is placed on the desk, making people's heads swell.

But there is no way, this big topic involves too many aspects.

Just like building a car, it requires the cooperation of many factories, and it is impossible for one factory to make all the parts.

Yang Ping wanted to focus on the core technology. Although he planned to cooperate with Takahashi, he would not have any hope for the Japanese. It was only an alternative for the branch line.

Yang Ping's main line plan has been formed, and he needs to find several domestic partners.

The genetic laboratory of Nandu Medical University is the object of his plan to cooperate to obtain or synthesize induced proteins.

In the subject of using stem cells to cultivate muscle cells, there are two core technologies that have emerged, induced differentiation technology and micro-scaffold technology. The third core technology in the future is cell structure stabilization technology.

Yang Ping searched for micro-support technology for a long time, and finally found a new startup company in Pengcheng called Mofang New Materials Company. Its 3D printing technology can achieve 15-micron printing. Although it is not enough, it is very promising.

This is a company founded by a group of returnee doctors. I don't know if this team has the ability to complete the research and development of micro stents. This is the only hope of domestic companies.

Only when these two partners are found, will the project hopefully be completed. Yang Ping intends to take time to negotiate one by one.

If the University of Tokyo can cooperate with me and share technology, I can digest and absorb their technology, and then improve it, which will shorten a lot of time.

But this kind of hope is not big, Yang Ping is not a person with illusions.

Therefore, in the mainline plan, we can only gnaw this bone from scratch.

Overtaking on a curve is something that has never happened. Technology can only take one step at a time. To surpass others, you can only rely on speed.

Funding for scientific research is also a big problem. The first phase of the fund needs about 30 million yuan.

This investment is huge, depending on the applied scientific research fund, even if it succeeds, it can be up to 1 million.

A million dollars is a drop in the bucket. If the follow-up investment in this topic is counted, it will be in the billions.

If there is not enough funds, the project will be difficult to run. These are very real problems. He now thinks what Xiao Su said is very correct.

If one day, if you can come up with tens of billions of funds at will, you will not worry about this amount of money.

Someone knocked on the door, it should be Song Zimo who finished the operation.

"I originally asked you to write it, but you are going to have a competition operation. I have already written it. This is the project plan I wrote." Yang Ping pointed to the thick stack of documents on the desk.

Song Zimo browsed the overview: "Why didn't you write about this research funding?"

"It's not that I don't write it. I can't write it for the time being. It costs 30 million for the first issue." Yang Ping said with a smile.

Song Zimo sucked in a breath: "The first phase costs tens of millions. This is a big issue at the level of 100 million yuan. Do we have a little—"

Yang Ping waved his hand: "Just do this project. I'll raise the money."

Yang Ping felt that it was time to start, and he could not postpone it any longer.

Start now, wait until the Golden Knife Award wins the championship and get the reward of the system space laboratory, then this topic has already started work, and you can exert your strength.

Now Yang Ping feels that if he really wants to do something, it will not work without money.

Huawei invests tens of billions of R\u0026D funds every year, and it lasts for more than ten years before the Kirin chip comes out.

How can other companies have this courage and vision, and this is an endless investment.

Compared with this kind of arduous technology research and development, building a few houses can make a lot of money. Everyone likes the latter, making money quickly and easily.

Duke University and the University of Tokyo have invested millions of dollars in this project, which are all in the early stage. They intend to continue to invest hundreds of millions of dollars in research and development funds in this project.

"All kinds of scientific research funds, if you can get one million, it has already reached the top. The hospital's money, the Overseas Chinese Foundation, even if Director Han and President Xia agree, it will be useless. The money belongs to the hospital, not the individual. It's impossible for Wan Lai to do scientific research for you." Song Zimo was very worried.

Tens of millions is not a small amount. If it is a business, it may also attract venture capital. Who is willing to do this kind of scientific research and lose money.

"I'll find a way about money." When Yang Ping had an idea, he already thought of difficulties.

"Thirty million yuan. Some great professors may not get thirty million yuan in scientific research funds in their lifetime." Song Zimo felt that the money was too much.

"You can do the competition surgery with peace of mind. I will discuss this matter. The subject must be done." Yang Ping is beyond doubt.

"Okay, no matter what, I support you. No matter how much money there is, there will be a number. Let's find a way together." Song Zimo fully supported Yang Ping.

He was going to organize everyone to review today's surgery and explain how Yang Ping could raise money together when he had time.

In the WeChat group on the mobile phone, Wei Danian's gene sequencing finally came to an end.

Some congenital diseases were excluded, glucose 6-phosphatase deficiency, pyruvate dehydrogenase and carboxylase deficiency, fructose 1,6 bisphosphatase deficiency, oxidative phosphorylation deficiency, these known congenital causes of lactic acidosis Diseases do not exist in Wei Danian.

The most advanced genetic testing technology in the country was used, but it was still in vain.

Dr. Wen Yulin's gene sequencing report, written dozens of pages, made a detailed report from the sequencing method, the equipment used, and the sequencing results.

Dr. Wen asked whether to continue to scale up the sequencing, to analyze some precursor molecules and metabolites, and even to re-sequence the genes, which is a huge project.

Even gene sequencing has not found the problem, is there any need to continue?

Such rare cases are the most precious resource, and it would be a pity to give up like this.

However, it is impossible to concentrate all energy on genetic testing of Wei Danian in the genetic experiment of Nandu Medical University, and there are still many tasks to be done.

If it wasn't for Su Nanchen's face, how could people accept such a human task.

Yang Ping suddenly remembered, didn't his system have a case push function recently, and he could carry out comprehensive medical activities for the pushed cases.

He entered the system space, used the function of case push, constantly changed the keywords, and narrowed the push range. Finally, through precise push, he obtained a case that was very similar to Wei Danian.

Yang Ping conducted the most extensive inspection of this experimental body, including all kinds of laboratory and equipment inspections.

But no clues were found, so an attempt was made to perfect the patient's genetic sequencing.

In reality, inspection methods are available in the system space, and inspections are performed in the system space without queuing, and the resources are all around the case.

A magical thing happened. A few hours later, the fourth-generation gene sequencing technology was completed, and a gene sequencing report of dozens of pages came out.

After reading the genetic test report, still no cause was found.

Yang Ping did several more gene sequencings, and this time the huge inspection cost him tens of thousands of points.

However, compared to simulated surgery, the consumption of these points can be tolerated.

Finally, a report showed that there is a mutation in the ATP5F1D gene, and this gene is involved in the function of mitochondria. It is the mutation of this gene that causes problems in the metabolism of pyruvate, resulting in the accumulation of lactic acid.

"Can you continue to test, use the fourth-generation gene sequencing technology to focus on the ATP5F1D gene, and do it a few more times, there may be a mutation in this gene."

Yang Ping left a message in the group.

"I'm very sorry, the fourth-generation sequencing instrument is currently unavailable." Dr. Wen expressed his regret, and he has been very busy with his subjects recently.

Ten minutes later, Dr. Wen made an OK gesture.

"If we re-sequence comprehensively, we will not be able to free up resources at all, and only accurate detection of the ATP5F1D gene can be arranged."

One can imagine the difficulty of looking for a lost treasure for every household in the entire city.

It is much easier to search only one house now.

Yang Ping used this case push function for the first time. He did not know whether the inspection in the system space was instructive in reality.

"We use the fourth-generation gene sequencing technology, and the results can be produced in a few hours, and we will start doing it tomorrow." Dr. Wen added.

In fact, Su Nanchen saw the conversation in the group and called Lin Lan, who was willing to continue to help with the test.

Lin Lan is the director of the genetic laboratory of Nandu Medical University, a doctoral tutor, and also has an identity: Su Nanchen's future wife.

Lin Lan arranged it herself, and Wen Yulin would definitely do it. Lin Lan was her doctoral supervisor.