The Last Alchemist
Chapter 39 The Birth of the First Miracle Medicine in History (Part 1)
Another dizzy experience, five minutes later, Rosen finally landed on the ground.
His head was shaken like a paste, and as soon as he landed, he staggered to the side of the street, holding on to the wall, and it took a long time to recover.
Turning back, he was standing at the place where he was just taken away. The only difference was that the sky was a little darker. If he hadn't had three more alchemy bottles on him, he really doubted that the experience just now was a dream.
'Veronica~Veronica, what a strange woman, with a powerful force beyond the high-level vampire, a beautiful appearance, and a proud personality, but it seems to follow some rules. What kind of monster is this? '
'The town is so big, which wooden house would she live in? '
Rosen turned around and looked around, and could only see the dark streets and muddy roads that smelled of human and animal feces. Compared with the warm and exquisite room just now, it was simply the difference between hell and heaven.
'Forget it, she spent so much effort to hide herself, which already showed that she didn't want me to know her whereabouts. She is much stronger than me and more terrifying than Annie. I'd better try not to provoke her as much as possible. '
Rosen didn't think about it anymore and hurried back to the small courtyard where he lived.
Passing by a small restaurant along the way, the aroma of food made him feel moved, and he couldn't help patting his head: 'Oh, I haven't been home for a day, Mary and her daughter must be starving. '
He immediately walked into the restaurant, looked at the simple menu, and paid for all the most expensive roast chickens on the menu. There were only two roast chickens in total, which were roasted oily and fragrant. After smelling it, Rosen felt his saliva increase.
He had a big appetite now, and this was not enough, so he bought another bag of herbal baked eggs, and then quickened his pace to the courtyard.
Arriving in the courtyard, Rosen carefully closed the gate, lit the lantern, drew a large bucket of water from the well in the courtyard, and then carried the food to the wine cellar.
At night, the wine cellar was pitch black and nothing could be seen. Rosen was a little nervous and stood at the entrance and shouted, "Sister Mary? Sister Mary?"
"Hey~ I'm here." A response came from inside.
Rosen breathed a sigh of relief and then carried the lantern and food into the wine cellar.
In the dim light of the lantern, Rosen saw Mary and little Alice sitting on the bedding, both of them staring at the exit of the wine cellar. When they saw Rosen, little Alice happily shouted, "Brother."
Sister Mary was obviously relieved.
Rosen felt guilty and put himself in their shoes. If someone made him stay in the dark cellar all day, relying on others for food and drink, and someone could break in at any time to drag him out and burn him to death, he would definitely be panicked.
He quickly explained, "I'm so sorry, I was so busy today."
Mary smiled and shook her head, "Sir, don't worry about us, there is food and drink here, we are all fine."
Rosen felt more and more ashamed. He hung the lantern on the wall, and then handed the roast chicken and the cloth bag of herbal baked eggs to Aunt Mary: "Here, you eat first, I'll go get some clean water from outside."
Mary opened the paper bag and saw that the food was so rich, she was immediately very uneasy and was about to hand it back to Rosen: "Sir, it doesn't have to be so good, we can just eat a little."
Rosen scratched his head: "Take it and eat it. Little Alice is still growing."
After that, he fled to the entrance of the wine cellar to get clean water. When he brought the clean water back, he saw Mary still sitting there with the papyrus bag, and the food was not touched. Although little Alice looked at the roast chicken eagerly and swallowed her saliva, she did not speak.
Seeing Rosen coming back, Mary said to Alice, "Hurry up and thank your brother."
Little Alice immediately said, "Thank you, brother."
Rosen felt mixed emotions. He could feel Mary's cautiousness, fearing that she would upset him. He walked over, tore off a leg from the roasted chicken and handed it to Alice, "Eat it, eat it until you are full. I will start extracting the medicine for you later."
Little Alice was really greedy, but after taking the chicken leg, she still didn't eat it. Instead, she turned her head and looked at Mary. After Mary nodded, she ate it voraciously.
Rosen put the flint on the side of the blanket and said, "Sister Mary, the lantern and flint are here. At night, if you feel stuffy in the wine cellar, you can take Alice for a walk in the yard."
"Okay." This time Mary didn't refuse. It was really stuffy to stay in the wine cellar all day without light.
After the explanation, Rosen was hungry. He picked up another roast chicken and started to eat it. He took a few bites, ate a herbal baked egg, and then drank a sip of water to moisten his throat. Soon, he was full.
After a burp, Rosen said goodbye and left the wine cellar. He walked to a corner of the yard and carried the bamboo baskets filled with various moldy fruits to his room.
After arriving in the room and lighting the candles, Rosen did not rush to start, but first summarized the things at hand.
He now has four things on hand, namely teaching Savi mirror grinding technology, making advanced magic mirrors for the baron, extracting penicillin, and making the weapon "Spiral Sprayer".
The first thing has to be taught tomorrow. Time is tight, but the workload is small. It's nothing more than drawing a few pictures and introducing the principle. The second thing is a bit complicated, but there is plenty of time, so it can be delayed for the time being. As for making the spiral sprayer, he wanted to start immediately, but the materials were insufficient and he couldn't find them in the middle of the night, so he had to put it aside for the time being.
After planning, the most important thing now is to extract penicillin. As for Savy's matter, he can take some time to do it when refining the medicine.
After thinking it over, Rosen started immediately.
In the middle of the room, there is a large table two meters long and one meter wide. Rosen took out the glass containers prepared during the day, filled them with clean water, and then sterilized the water with alchemical power.
After finishing, Rosen took out a roll of parchment, a feather pen, and ink, and then picked up the moldy fruit, activated the alchemical power, and observed the penicillium in it.
Penicillium is a genus that contains more than 200 different species of penicillium, of which only a dozen can secrete penicillin. Therefore, Rosen's first step is to pick out the correct penicillium.
There are more than 30 kilograms of fruits in the bamboo basket, and there are more than a dozen kinds. Rosen observed them one by one. Every time he observed one, he used a feather pen to draw the structural characteristics of penicillium on the parchment, and then sorted and put the fruits infected with the same kind of penicillium.
Compared to molecular atoms, Penicillium is simply a giant. With the help of alchemy, Rosen can see it clearly, which makes his work progress very quickly.
In about two and a half hours, Rosen recorded a total of 17 types of Penicillium, and drew illustrations for each type of Penicillium, depicting the most striking features.
Then, Rosen proceeded to the second step: determine penicillin.
Rosen did not know the specific molecular structure of penicillin, so he could only use the benzene method.
He took out a dagger, scraped each type of Penicillium from the moldy fruit, and dissolved it in the clear water of the glass.
Rosen tried hard to recall the information he had seen about penicillin, not to mention that he really remembered some useful information.
He remembered that different Penicillium species secrete penicillin in different ways. There are generally two ways, one is intercellular fluid and the other is intracellular fluid.
If penicillium is simply dissolved with clear water, if penicillin exists outside the cell, it can be detected, if it is intracellular fluid, it will be missed.
In order to avoid mistakes, Rosen activated the alchemical power again and smashed all the cell structures of Penicillium in the water into a paste.
In this way, if there is one of these Penicillium that can secrete penicillin, it will definitely appear in these clear waters.
But how to determine this?
Rosen has also thought of a way. He took out the wooden box and carefully put 17 glasses filled with penicillin solution into it, and then took the box and went to the wine cellar.
In the wine cellar, Little Alice and Sister Mary were already asleep, but Sister Mary slept very lightly. When she heard the noise, she woke up immediately. When she saw that it was Rosen, she was about to speak, but was interrupted by him.
‘Shh~’ Rosen pointed at Little Alice and whispered: “Sister Mary, I am looking for treatment drugs. In order to determine the active ingredients, I need to do some experiments on you.”
“No problem.” Mary said without hesitation.
Rosen opened the wooden box, took out the specially prepared sterilized linen, and then motioned Mary to roll up her sleeves.
Mary did as she was told. After she rolled up her sleeves, she could see that her arms were covered with red papules, and most of them were ulcerated. In several places, the ulcers were even connected together, which was shocking.
Rosen took a deep breath, took out a feather pen, and first found 20 independent abscesses on Mary's arm and numbered them separately. Then, he activated the alchemical power to sense the state of the bacteria in the abscesses. Every time he sensed one, he used a feather pen to draw on parchment and make a detailed text description of the bacteria.
After making a record, Rosen took the sterilized linen cloth, dipped it in different penicillium solutions, and gently applied it to the abscesses. Finally, he deliberately left 3 abscesses as a control group.
Controlling variables as much as possible, leaving a control group, and keeping detailed experimental records, Rosen did everything he could, but the conditions were really simple, and he could only do this much at most.
When applying the penicillium solution, Mary groaned from time to time, stimulating the abscess wound made her very painful.
"Bear with it, it will be healed soon." Rosen comforted softly.
After the application, Rosen activated the alchemical power again and carefully observed the survival of the bacteria in the abscesses.
Time passed by minute by minute, and after about half an hour, the results began to appear clearly.
Of the 17 abscesses smeared with penicillin solution, 14 of them had basically no change in the bacteria in the abscesses, and there was basically no difference compared with the control group, but there were 3 abscesses with a significant decrease in the number of bacteria, among which the abscesses corresponding to the No. 15 penicillin solution had a sharp decrease of 90%!
Rosen was excited: "I found it! Penicillin is in the No. 15, No. 9, and No. 7 solutions. '
Originally, to determine whether a drug is truly effective for the human body, a "large sample randomized double-blind trial" must be conducted. The whole process is time-consuming and costly.
But Rosen didn't need to do this. First, the efficacy of penicillin has been widely verified on Earth; second, he didn't have the conditions and time to do more verification. He could only do his best to be extremely rigorous under simple conditions.
After finding penicillin, Rosen scooped a spoonful of water, disinfected it with alchemical power, and then used it to clean the penicillin solution on Sister Mary's arm.
After washing, Rosen whispered: "Sister Mary, don't worry, I have found a truly effective medicine. Next, I will start preparing the medicine. If nothing unexpected happens, I will be able to start treating you soon."
Mary's single eye lit up slightly, but soon dimmed again.
"What's wrong?" Rosen asked.
Mary whispered, "Lord Romley used to say this to us, but..."
Rosen understood, and he emphasized his tone and said seriously, "Believe me, my medicine is different from Romley's."
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